
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Frunexian
Therapeutic Area : Hematology
Study Phase : Phase I
Recipient : eXIthera Pharmaceutical
Deal Size : $15.0 million
Deal Type : Acquisition
Cadrenal Acquires eXIthera’s Factor XIa Inhibitors Portfolio
Details : The Acquisition enhances the Company’s pipeline by adding novel assets, including frunexian, a first-in-class, Phase 2-ready IV Factor XIa inhibitor in acute and chronic anticoagulation settings.
Product Name : EP-7041
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 15, 2025
Lead Product(s) : Frunexian
Therapeutic Area : Hematology
Highest Development Status : Phase I
Recipient : eXIthera Pharmaceutical
Deal Size : $15.0 million
Deal Type : Acquisition

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Lead Product(s) : Tecarfarin
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Abbott Laboratories
Deal Size : Undisclosed
Deal Type : Collaboration
Cadrenal, Abbott Collaborate on Tecarfarin Study in HeartMate 3™ LVAD Patients
Details : The collaboration aims to advance the clinical development of ATI-5923 (tecarfarin), which is being evaluated in patients with advanced heart failure.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 04, 2025
Lead Product(s) : Tecarfarin
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Abbott Laboratories
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Tecarfarin
Therapeutic Area : Hematology
Study Phase : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $4.7 million
Deal Type : Public Offering
Cadrenal Therapeutics Announces Exercise of Warrants for $4.7 Million Gross Proceeds
Details : The proceeds from the financing will be used to advance the company's lead development candidate, ATI-5923 (tecarfarin). It is designed to prevent heart attacks, and strokes.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
November 01, 2024
Lead Product(s) : Tecarfarin
Therapeutic Area : Hematology
Highest Development Status : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $4.7 million
Deal Type : Public Offering

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Lead Product(s) : Tecarfarin
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II/ Phase III
Sponsor : H.C. Wainwright & Co
Deal Size : $5.1 million
Deal Type : Financing
Cadrenal Therapeutics Raises $5.1 Million via At-The-Market Facility
Details : The net proceeds will be used in developing ATI-5923 (tecarfarin), a new vitamin K antagonist (VKA), prepare for our pivotal Phase 3 trial.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 24, 2024
Lead Product(s) : Tecarfarin
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : H.C. Wainwright & Co
Deal Size : $5.1 million
Deal Type : Financing

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Lead Product(s) : Tecarfarin
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Abbott Laboratories
Deal Size : Undisclosed
Deal Type : Collaboration
Cadrenal and Abbott Collaborate on Novel Anticoagulant Tecarfarin for LVAD Patients
Details : The collaboration aims to advance the novel anticoagulant ATI-5923 (tecarfarin), designed to prevent heart attacks, strokes, and deaths due to blood clots in patients with implanted cardiac devices.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
August 06, 2024
Lead Product(s) : Tecarfarin
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Abbott Laboratories
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Tecarfarin,Warfarin Sodium
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II/ Phase III
Sponsor : The Sage Group
Deal Size : Undisclosed
Deal Type : Partnership
Details : Under the partnership, Sage Group will assist Cadrenal in exploring strategic partnerships, co-development and licensing agreements for ATI-5923 (tecarfarin), a late-stage, novel, oral and reversible anticoagulant designed to prevent heart attacks, strok...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 12, 2023
Lead Product(s) : Tecarfarin,Warfarin Sodium
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : The Sage Group
Deal Size : Undisclosed
Deal Type : Partnership

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Lead Product(s) : Tecarfarin
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Tecarfarin is an vitamin K antagonist (VKA), taken once a day as an oral anticoagulant like warfarin, which is investigated for the treatment of patients with antiphospholipid syndrome (APS) who require chronic anticoagulation.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 30, 2023
Lead Product(s) : Tecarfarin
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tecarfarin
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Tecarfarin is an vitamin K antagonist (VKA), taken once a day as an oral anticoagulant like warfarin, which is investigated for the treatment of implanted medical devices for heart diseases.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 01, 2023
Lead Product(s) : Tecarfarin
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tecarfarin
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Boustead Securities
Deal Size : $7.0 million
Deal Type : Public Offering
Cadrenal Therapeutics (Nasdaq: CVKD) Announces Closing of Initial Public Offering
Details : The Company intends to use the net proceeds in developing tecarfarin, a novel cardiorenal therapy for the prevention of systemic thromboembolism of cardiac origin in patients with end-stage renal disease, or ESRD, and atrial fibrillation (irregular heart...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 24, 2023
Lead Product(s) : Tecarfarin
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Boustead Securities
Deal Size : $7.0 million
Deal Type : Public Offering

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Lead Product(s) : Tecarfarin
Therapeutic Area : Hematology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Tecarfarin is a Vitamin K antagonist oral anticoagulant designed to target a different pathway than the most commonly prescribed drugs used in the treatment of thrombosis and AFib.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 23, 2023
Lead Product(s) : Tecarfarin
Therapeutic Area : Hematology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
