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    Mission CDMO team brings reliability, resourcefulness, & responsiveness in executing your development project.

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    About

    BITT’s dominant antibody antagonist antibody platform (DOMabTM) is a proprietary discovery platform for the development of antagonist monoclonal antibodies to the TNF superfamily. DOMab antibodies create unique surface stabilization of anti-parallel dimers for altering intracellular signaling. For TNF superfamily proliferative pathways (such as TNFR2, TRAIL and HVEM), antagonism causes cell death. For death receptors (such a...
    BITT’s dominant antibody antagonist antibody platform (DOMabTM) is a proprietary discovery platform for the development of antagonist monoclonal antibodies to the TNF superfamily. DOMab antibodies create unique surface stabilization of anti-parallel dimers for altering intracellular signaling. For TNF superfamily proliferative pathways (such as TNFR2, TRAIL and HVEM), antagonism causes cell death. For death receptors (such as CD40, CD27 and OX40), antagonism permits cell growth. Our technology’s ability to create antibodies that target only rapidly proliferating cells opens the door to TNF superfamily targets.

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    Winchester, Virginia
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    NEWS #PharmaBuzz

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    BITT Announces FDA Acceptance of IND for TNFR2 Antibody
    BITT Announces FDA Acceptance of IND for TNFR2 Antibody

    18 Aug 2023

    // BUSINESSWIRE

    https://www.businesswire.com/news/home/20230818088156/en

    BUSINESSWIRE
    18 Aug 2023
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