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Biorchestra
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South Korea
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Under the agreement, Global Biopharmaceutical will Leverage Biorchestra Targeting Technology Platform, BDDS™ to Develop Nucleic Acid Therapies, including BMD-001, for Treatment of Neurological Disorders in Multiple Targets.


Lead Product(s): BMD-001

Therapeutic Area: Neurology Product Name: BMD-001

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $861.0 million Upfront Cash: Undisclosed

Deal Type: Agreement March 27, 2023

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BMD-001 (or BDDS : miR-485-3p ASO) is an antisense oligonucleotides encapsulated with proprietary Brin polymer to cross blood-brain barrier and plasma membrane of microglia, astrocyte and neuron to degrade the microRNA 485-3p and treat neuroinflammation and neurodegeneration.


Lead Product(s): BMD-001

Therapeutic Area: Neurology Product Name: BMD-001

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 09, 2022

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Under the collaboration agreement, BIORCHESTRA, that develops RNA therapeutics for neurodegenerative diseases, will be responsible for target discovery, selection, and synthesis via its in-house technology by using antisense oligonucleotides.


Lead Product(s): Antisense Oligonucleotides

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Large molecule

Partner/Sponsor/Collaborator: SK Biopharmaceuticals

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration January 05, 2022

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