Selinexor (KPT-330) API Manufacturers | Suppliers | Drug Master Files (DMF) | CEP

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01

Novasep

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Health 2.0 Conference

Not Confirmed

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02

Conscientia Industrial

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Health 2.0 Conference

Not Confirmed

03

Sandoo Pharmaceuticals and Chemcia...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Health 2.0 Conference

Not Confirmed

04

Beijing Sjar Technology Developmen...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Health 2.0 Conference

Not Confirmed

Looking for 1393477-72-9 / Selinexor API manufacturers, exporters & distributors?

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API | Excipient name

Selinexor

Synonyms

Kpt-330, 1393477-72-9, Xpovio, Selinexor (kpt-330), Selinexor free base, (z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1h-1,2,4-triazol-1-yl)-n'-(pyrazin-2-yl)acrylohydrazide

Cas Number

1393477-72-9

Unique Ingredient Identifier (UNII)

31TZ62FO8F

About Selinexor

Selinexor is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic activity. Selinexor modifies the essential CRM1-cargo binding residue cysteine-528, thereby irreversibly inactivates CRM1-mediated nuclear export of cargo proteins such as tumor suppressor proteins (TSPs), including p53, p21, BRCA1/2, pRB, FOXO, and other growth regulatory proteins. As a result, this agent, via the approach of selective inhibition of nuclear export (SINE), restores endogenous tumor suppressing processes to selectively eliminate tumor cells while sparing normal cells. CRM1, the major export factor for proteins from the nucleus to the cytoplasm, is overexpressed in a variety of cancer cell types.

Selinexor (KPT-330) Manufacturers

A Selinexor (KPT-330) manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Selinexor (KPT-330), including repackagers and relabelers. The FDA regulates Selinexor (KPT-330) manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Selinexor (KPT-330) API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Selinexor (KPT-330) manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Selinexor (KPT-330) Suppliers

A Selinexor (KPT-330) supplier is an individual or a company that provides Selinexor (KPT-330) active pharmaceutical ingredient (API) or Selinexor (KPT-330) finished formulations upon request. The Selinexor (KPT-330) suppliers may include Selinexor (KPT-330) API manufacturers, exporters, distributors and traders.

click here to find a list of Selinexor (KPT-330) suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Selinexor (KPT-330) Manufacturers | Traders | Suppliers

We have 4 companies offering Selinexor (KPT-330)

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Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.