Onco360 Selected as the Preferred National Specialty Pharmacy Partner for XPOVIO
Karyopharm Shares Data at ASH 2023 Showing Strong SVR and TSS Durability
NEWTON, Mass., Oct. 30, 2023 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that it has entered into a clinical trial collaboration and supply agreement with Bristol-Myers Squibb (NYSE: BMY) to evaluate the company's proprietary investigational cereblon E3 ligase modulator (CELMoD™) agent mezigdomide in combination with Karyopharm's selinexor, an approved first-in-class inhibitor of Exportin 1 (XPO1), plus dexamethasone in patients with relapsed/refractory multiple myeloma.
Antengene Corporation Limited, a leading innovative, commercial-stage global biopharmaceutical company, and Hansoh Pharmaceutical Group Company Limited (Hansoh Pharma), a leading innovation-driven pharmaceutical company, announced the entrance into a collaboration agreement between Antengene and Hansoh Pharma for the commercialization of Xpovio in the mainland of China.
The biotech, which has struggled to grow sales of its medicine Xpovio, is laying off 20% of its staff and focusing on late-stage studies in endometrial cancer and myelofibrosis.
NEWTON, Mass., June 28, 2023 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced the initiation of a pivotal Phase 3 clinical trial (XPORT-MF-034) (NCT04562389) to assess the efficacy and safety of once-weekly selinexor 60mg in combination with ruxolitinib in JAKi-naïve patients with myelofibrosis.