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USDMF
CEP/COS
JDMF
WC
Looking for 1401028-24-7 / Oliceridine API manufacturers, exporters & distributors?
Oliceridine manufacturers, exporters & distributors
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PharmaCompass offers a list of Oliceridine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Oliceridine manufacturer or Oliceridine supplier for your needs.
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API | Excipient name
Oliceridine
Synonyms
Trv130, 1401028-24-7, Trv-130, Olinvyk, Oliceridine [usan], Mcn858tcp0
Unique Ingredient Identifier (UNII)
MCN858TCP0
About Oliceridine
Severe acute pain occurs through nociceptive signalling involving both ascending and descending spinal pathways, in which nerve conductance is mediated in part by the action of opioid receptors. Opioid receptors are seven-transmembrane G-protein-coupled receptors (GPCRs), of which the -opioid receptor subtype is predominantly targeted by and is responsible for the effects of opioid agonists. However, due to the ability of some opioid agonists to bind to other targets, as well as activation of additional downstream pathways from opioid receptors such as those involving -arrestin, the beneficial analgesic effects of opioids are coupled with severe adverse effects such as constipation and respiratory depression. Oliceridine (formerly known as TRV130) is a "biased agonist" at the -opioid receptor by preferentially activating the G-protein pathway with minimal receptor phosphorylation and recruitment of -arrestin. By acting as a biased agonist, oliceridine provides comparable analgesia compared with traditional opioids such as [morphine] at a comparable or decreased risk of opioid-related adverse effects such as constipation and respiratory depression. Oliceridine was first reported in 2013, but was initially not approved by the FDA due to concerns raised by the Anesthetic and Analgesic Drug Products Advisory Committee. Oliceridine gained FDA approval on August 7, 2020, and is currently marketed by Trevena Inc as OLINVYK.
Oliceridine Manufacturers
A Oliceridine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oliceridine, including repackagers and relabelers. The FDA regulates Oliceridine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oliceridine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Oliceridine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
Oliceridine Suppliers
A Oliceridine supplier is an individual or a company that provides Oliceridine active pharmaceutical ingredient (API) or Oliceridine finished formulations upon request. The Oliceridine suppliers may include Oliceridine API manufacturers, exporters, distributors and traders.
click here to find a list of Oliceridine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
Oliceridine Manufacturers | Traders | Suppliers
Oliceridine Manufacturers, Traders, Suppliers
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We have 1 companies offering Oliceridine
Get in contact with the supplier of your choice:
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Arevipharma
Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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