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Looking for 1401028-24-7 / Oliceridine API manufacturers, exporters & distributors?

Oliceridine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Oliceridine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Oliceridine manufacturer or Oliceridine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Oliceridine manufacturer or Oliceridine supplier.

PharmaCompass also assists you with knowing the Oliceridine API Price utilized in the formulation of products. Oliceridine API Price is not always fixed or binding as the Oliceridine Price is obtained through a variety of data sources. The Oliceridine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Oliceridine

Synonyms

Trv130, 1401028-24-7, Trv-130, Olinvyk, Oliceridine [usan], Mcn858tcp0

Cas Number

1401028-24-7

Unique Ingredient Identifier (UNII)

MCN858TCP0

About Oliceridine

Severe acute pain occurs through nociceptive signalling involving both ascending and descending spinal pathways, in which nerve conductance is mediated in part by the action of opioid receptors. Opioid receptors are seven-transmembrane G-protein-coupled receptors (GPCRs), of which the -opioid receptor subtype is predominantly targeted by and is responsible for the effects of opioid agonists. However, due to the ability of some opioid agonists to bind to other targets, as well as activation of additional downstream pathways from opioid receptors such as those involving -arrestin, the beneficial analgesic effects of opioids are coupled with severe adverse effects such as constipation and respiratory depression. Oliceridine (formerly known as TRV130) is a "biased agonist" at the -opioid receptor by preferentially activating the G-protein pathway with minimal receptor phosphorylation and recruitment of -arrestin. By acting as a biased agonist, oliceridine provides comparable analgesia compared with traditional opioids such as [morphine] at a comparable or decreased risk of opioid-related adverse effects such as constipation and respiratory depression. Oliceridine was first reported in 2013, but was initially not approved by the FDA due to concerns raised by the Anesthetic and Analgesic Drug Products Advisory Committee. Oliceridine gained FDA approval on August 7, 2020, and is currently marketed by Trevena Inc as OLINVYK.

Oliceridine Manufacturers

A Oliceridine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oliceridine, including repackagers and relabelers. The FDA regulates Oliceridine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oliceridine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Oliceridine Suppliers

A Oliceridine supplier is an individual or a company that provides Oliceridine active pharmaceutical ingredient (API) or Oliceridine finished formulations upon request. The Oliceridine suppliers may include Oliceridine API manufacturers, exporters, distributors and traders.

Oliceridine GMP

Oliceridine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Oliceridine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oliceridine GMP manufacturer or Oliceridine GMP API supplier for your needs.

Oliceridine CoA

A Oliceridine CoA (Certificate of Analysis) is a formal document that attests to Oliceridine's compliance with Oliceridine specifications and serves as a tool for batch-level quality control.

Oliceridine CoA mostly includes findings from lab analyses of a specific batch. For each Oliceridine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Oliceridine may be tested according to a variety of international standards, such as European Pharmacopoeia (Oliceridine EP), Oliceridine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oliceridine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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