Enasidenib mesylate API Manufacturers | Suppliers | Exporters

Looking for 1802003-09-3 / Enasidenib API manufacturers, exporters & distributors?

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API | Excipient name

Enasidenib

Synonyms

1446502-11-9, Ag-221, Ag-221 (enasidenib), Enasidenib [inn], Cc-90007 free base, Idhifa

Cas Number

1802003-09-3

Unique Ingredient Identifier (UNII)

3T1SS4E7AG

About Enasidenib

Enasidenib is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential antineoplastic activity. Upon administration, enasidenib specifically inhibits various mutant forms of IDH2, including the IDH2 variants R140Q, R172S, and R172K, which inhibits the formation of 2-hydroxyglutarate (2HG). This may lead to both an induction of cellular differentiation and an inhibition of cellular proliferation in IDH2-expressing tumor cells. IDH2, an enzyme in the citric acid cycle, is mutated in a variety of cancers; it initiates and drives cancer growth by blocking differentiation and the production of the oncometabolite 2HG.

Enasidenib mesylate Manufacturers

A Enasidenib mesylate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Enasidenib mesylate, including repackagers and relabelers. The FDA regulates Enasidenib mesylate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Enasidenib mesylate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

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Enasidenib mesylate Suppliers

A Enasidenib mesylate supplier is an individual or a company that provides Enasidenib mesylate active pharmaceutical ingredient (API) or Enasidenib mesylate finished formulations upon request. The Enasidenib mesylate suppliers may include Enasidenib mesylate API manufacturers, exporters, distributors and traders.

click here to find a list of Enasidenib mesylate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Enasidenib mesylate Manufacturers | Traders | Suppliers

We have 3 companies offering Enasidenib mesylate

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Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

List of Enasidenib mesylate Active Pharmaceutical Ingredient (API) suppliers/manufacturers & exporters