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    List of Drug Master Files (JDMF) of Active Pharmaceutical Ingredients (APIs) submitted by Safc to the Review Authority in Japan (PMDA). Original Data : PMDA

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    01 Dactinomycin USP (1)

    02 Media/Media Additives GS2-N Low B12 No Hydrocort (2)

    03 Media/Media Additives ・Trace Element E 1000X Solution (1)

    04 Medium / Medium Additive / IMB8 (1)

    05 Medium / Medium Additive / IMB9 (1)

    06 Medium / Medium Additive / IMF8 (1)

    07 Medium / Medium Additive / PER2 (1)

    08 Medium / Medium Additive ・ CHOKO Production Medium Powerer (2)

    09 Medium / Medium Additive ・ EX-CELL (TM) 6GRO w / L-Glutamine (2)

    10 Medium / Medium Additive ・ IMF9-2X (1)

    11 Medium / Medium Additive ・ TE1 (1)

    12 Medium / Medium Additives ・ CHO Kit 2 Iron Chelator Solution (1)

    13 Medium / Medium Additives ・ CHOKO FMA Powerer (2)

    14 Medium / Medium Additives ・ CHOKO FMB Powerer (2)

    15 Medium / Medium Additives ・ CHOKO Stock Culture Medium Powerer (2)

    16 Medium / Medium Additives-EX-CELL (TM) CD Hydrolysate Fusion Animal Coordinate Free, Chemically Defined (1)

    17 Medium / Medium Additives-EX-CELL ACF CHO Medium (1)

    18 Medium / Medium Additives-EX-CELL Advanced (TM) Modified (1)

    19 Medium / Medium Additives-EX-CELL Advanced CHO Feed 1 (1)

    20 Medium / Medium Additives-EX-CELL Advanced CHO Feed 1 (with glucose)　 (2)

    21 Medium / Medium Additives-EX-CELL Advanced CHO Feed 1 (without glucose) (2)

    22 Medium / Medium Additives-SuppAA-1 (1)

    23 Medium / media supplements · EX-CELL (TM) 325 PF CHO Protei n-Free Medium (Modified) (1)

    24 Medium / medium additive · C8862: EX-CELL CHO DHFR - Medium (1)

    25 Medium / medium additive · CHO Feed Bioreactor Supplement (1)

    26 Medium / medium additive · EX-CELL (TM) 302 (Modified 6827 2C) Animal Component Free Media w / o Sodium Bicarbonate (1)

    27 Medium / medium additive · EX-CELL 325 PF CHO Serum-Fr ee Medium for CHO Cells (1)

    28 Medium / medium additive · EX-CELL EBx GRO-Ⅰ Serum-Fre e Media (1)

    29 Medium / medium additive · EX-CELL EBx PRO-Ⅰ Serum-Fre e Media (1)

    30 Medium / medium additive · EX-CELL EBx PRO-Ⅰ Serum-Fre e Medium for Embryonic Stem Cells (1)

    31 Medium / medium additive · Ex-CELL EBx GRO-Ⅰ Serum-Fre e Medium for Embryonic Stem Cells (1)

    32 Medium / medium additive · Fatty Acid Supplement (1)

    33 Medium / medium additive · Sigma EX-CELL 302 Serum-Fr ee Medium for CHO Cells (1)

    34 Medium / medium additive · Sigma EX-CELL PF CHO Mediu m (Modified) (1)

    35 Medium / medium additive · StemlineⅡ Hematopoietic Stem C ell Expansion Medium (1)

    36 Medium/medium additive EX-CELL (R) 293 Serum-Free Medium for HEK 293 Cells (2)

    37 Medium/medium additive R17 (2)

    38 Medium/medium additive R7A-1 (2)

    39 Medium/medium additive R7B-2 w/o L-Tyrosine (2)

    40 Medium/medium additive ・F48 Low B12 no HC (2)

    41 Medium/medium additive ・R34B Medium (1)

    42 Medium/medium additive ・R36 Low B12 (2)

    43 Medium/medium additive ・Trace Element B Solution B (1000X) (1)

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    01 SAFC Biosciences, Inc. (29)

    02 SAFC Sigma-Aldrich Corporation. (1)

    03 SIGMA-ALDRICH ISRAEL Ltd. (1)

    04 Sigma-Aldrich Company Limited Trading As SAFC (17)

    05 Sigma-Aldrich Manufacturing, LLC. (6)

    06 Sigma-Aldrich manufacturing, LLC. (3)

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    01 U.S.A (57)

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    Dactinomycin USP

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    SIGMA-ALDRICH ISRAEL Ltd.
    2017-02-13
    2009-08-13
    221MF10187
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    Medium / medium additive · EX-CELL (TM) 302 (Modified ...

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    SAFC Biosciences, Inc.
    2018-01-15
    2018-01-15
    230MF40003
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    Medium / Medium Additive ・ EX-CELL (TM) 6GRO w / L-Gl...

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    Sigma-Aldrich Company Lim...
    2022-03-10
    2022-03-10
    304MF40011
    Second Avenue Heatherhous...
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    Medium / Medium Additive ・ EX-CELL (TM) 6GRO w / L-Gl...

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    SAFC Biosciences, Inc.
    2022-03-10
    2022-03-10
    304MF40012
    13804 West 107th Street L...
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    Medium / Medium Additives-EX-CELL Advanced CHO Feed 1 (...

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    SAFC Biosciences, Inc.
    2020-01-24
    2020-01-24
    302MF40001
    13804 West 107th Street L...
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    Medium / Medium Additives-EX-CELL Advanced CHO Feed 1 (...

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    Sigma-Aldrich Company Lim...
    2020-01-24
    2020-01-24
    302MF40004
    Second Avenue Heatherhous...
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    Medium/medium additive R7B-2 w/o L-Tyrosine

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    SAFC Biosciences, Inc.
    2022-05-18
    2022-05-18
    304MF40022
    13804 West 107th Street L...
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    Medium/medium additive R7B-2 w/o L-Tyrosine

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    Sigma-Aldrich Company Lim...
    2022-05-18
    2022-05-18
    304MF40021
    Second Avenue Heatherhous...
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    Media/Media Additives GS2-N Low B12 No Hydrocort

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    Sigma-Aldrich Company Lim...
    2022-12-23
    2022-12-23
    304MF40049
    Second Avenue Heatherhous...
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    Media/Media Additives GS2-N Low B12 No Hydrocort

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    SAFC Biosciences, Inc.
    2022-12-23
    2022-12-23
    304MF40050
    13804 West 107th Street L...
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