

08 Jan 2026
// GLOBENEWSWIRE
https://www.globenewswire.com/news-release/2026/01/08/3215201/0/en/Tisento-Therapeutics-Completes-Enrollment-in-PRIZM-a-Global-Phase-2b-Study-of-Zagociguat-for-the-Treatment-of-MELAS.html

20 Aug 2025
// GLOBENEWSWIRE
https://www.globenewswire.com/news-release/2025/08/20/3136285/0/en/First-PRIZM-Study-Participant-Enrolled-in-Tisento-Therapeutics-Open-Label-Extension-Study-in-MELAS.html

27 Jan 2025
// GLOBENEWSWIRE
https://www.globenewswire.com/news-release/2025/01/27/3015457/0/en/First-Participant-Dosed-in-Tisento-Therapeutics-Global-Phase-2b-PRIZM-Study-Evaluating-Zagociguat-for-the-Treatment-of-MELAS.html

11 May 2023
// GLOBENEWSWIRE
https://www.globenewswire.com/news-release/2023/05/11/2667449/0/en/Cyclerion-Announces-Definitive-Agreement-for-Zagociguat-and-CY3018.html