Please Wait
Applying Filters...
menu
    • menu
    Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

    Virtual Booth

    Contact Supplier

    With Virupaksha, you get a quality product with on-time delivery.

    Virtual Booth

    Contact Supplier

    pharmacompass-1-m-2025-11-24

    Virtual Booth

    An Enquiry

    Munit offers scalable GMP micronization and particle size engineering to enhance drug solubility, bioavailability, and performance.

    Virtual Booth

    Contact Supplier

    ChemExpress delivers end-to-end CRO & CDMO solutions for small molecules, biologics & new modalities with ICH-grade quality.

    Virtual Booth

    Contact Supplier

    pharmacompass-2-m-2025-11-03

    Virtual Booth

    An Enquiry

    Menu

    Sirpiglenastat

    DEVELOPMENTS

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 2079939-05-0, (-)-sirpiglenastat, Drp-104, Sirpiglenastat [usan], 9gge6a0zmk, Sirpiglenastat [inn]
    Molecular Formula
    C22H27N5O5
    Molecular Weight
    441.5  g/mol
    InChI Key
    LQNMCWOJACNQQM-PMACEKPBSA-N
    FDA UNII
    9GGE6A0ZMK
    SIRPIGLENASTAT is a small molecule drug with a maximum clinical trial phase of I (across all indications) and has 2 investigational indications.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    propan-2-yl (2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-6-diazo-5-oxohexanoate
    2.1.2 InChI
    InChI=1S/C22H27N5O5/c1-13(2)32-22(31)19(9-8-16(29)12-25-23)27-21(30)20(26-14(3)28)10-15-11-24-18-7-5-4-6-17(15)18/h4-7,11-13,19-20,24H,8-10H2,1-3H3,(H,26,28)(H,27,30)/t19-,20-/m0/s1
    2.1.3 InChI Key
    LQNMCWOJACNQQM-PMACEKPBSA-N
    2.2 Other Identifiers
    2.2.1 UNII
    9GGE6A0ZMK
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 2079939-05-0

    2. (-)-sirpiglenastat

    3. Drp-104

    4. Sirpiglenastat [usan]

    5. 9gge6a0zmk

    6. Sirpiglenastat [inn]

    7. Sirpiglenastat [who-dd]

    8. Sirpiglenastat (usan)

    9. L-norleucine, N-acetyl-l-tryptophyl-6-diazo-5-oxo-, 1-methylethyl Ester

    10. Propan-2-yl (2s)-2-((n-acetyl-l-tryptophyl)amino)-6-diazo-5-oxohexanoate

    11. (s)-isopropyl 2-((s)-2-acetamido-3-(1h-indol-3-yl)propanamido)-6-diazo-5-oxohexanoate

    12. Refchem:183238

    13. Drp104

    14. Glutamine Antagonist Drp-104

    15. Drp 104

    16. Sirpiglenastat?

    17. Orb1687484

    18. Chembl4650367

    19. Schembl20465436

    20. Schembl29495819

    21. Glxc-26739

    22. Ex-a10433

    23. Da-67601

    24. Hy-132832

    25. Cs-0204139

    26. D12008

    27. G18545

    28. Isopropyl(s)-2-((s)-2-acetamido-3-(1h-indol-3-yl)-propanamido)-6-diazo-5-oxo-hexanoate

    29. Propan-2-yl (2s)-2-[[(2s)-2-acetamido-3-(1h-indol-3-yl)propanoyl]amino]-6-diazo-5-oxohexanoate

    2.4 Create Date
    2019-01-26
    3 Chemical and Physical Properties
    Molecular Weight 441.5 g/mol
    Molecular Formula C22H27N5O5
    XLogP31.2
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count12
    Exact Mass Da
    Monoisotopic Mass Da
    Topological Polar Surface Area119
    Heavy Atom Count32
    Formal Charge0
    Complexity749
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count1
    Covalently Bonded Unit Count1