Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

Virtual Booth

Contact Supplier

With Virupaksha, you get a quality product with on-time delivery.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

DEVELOPMENTS

2 Drugs in Development

2 Drugs in Development

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

2DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

API REF. PRICE (USD/KG)

$ 0

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Regulatory FDF Prices

API/FDF Prices: Book a Demo to
explore the features and consider
upgrading later

MARKET PLACE

API

FDF

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 2079939-05-0, (-)-sirpiglenastat, Drp-104, Sirpiglenastat [usan], 9gge6a0zmk, Sirpiglenastat [inn]

Molecular Formula

C₂₂H₂₇N₅O₅

Molecular Weight

441.5 g/mol

InChI Key

LQNMCWOJACNQQM-PMACEKPBSA-N

FDA UNII

9GGE6A0ZMK

SIRPIGLENASTAT is a small molecule drug with a maximum clinical trial phase of I (across all indications) and has 2 investigational indications.

1 2D Structure

Sirpiglenastat

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

propan-2-yl (2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-6-diazo-5-oxohexanoate

2.1.2 InChI

InChI=1S/C22H27N5O5/c1-13(2)32-22(31)19(9-8-16(29)12-25-23)27-21(30)20(26-14(3)28)10-15-11-24-18-7-5-4-6-17(15)18/h4-7,11-13,19-20,24H,8-10H2,1-3H3,(H,26,28)(H,27,30)/t19-,20-/m0/s1

2.1.3 InChI Key

LQNMCWOJACNQQM-PMACEKPBSA-N

2.2 Other Identifiers

2.2.1 UNII

9GGE6A0ZMK

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 2079939-05-0

2. (-)-sirpiglenastat

3. Drp-104

4. Sirpiglenastat [usan]

5. 9gge6a0zmk

6. Sirpiglenastat [inn]

7. Sirpiglenastat [who-dd]

8. Sirpiglenastat (usan)

9. L-norleucine, N-acetyl-l-tryptophyl-6-diazo-5-oxo-, 1-methylethyl Ester

10. Propan-2-yl (2s)-2-((n-acetyl-l-tryptophyl)amino)-6-diazo-5-oxohexanoate

11. (s)-isopropyl 2-((s)-2-acetamido-3-(1h-indol-3-yl)propanamido)-6-diazo-5-oxohexanoate

12. Refchem:183238

13. Drp104

14. Glutamine Antagonist Drp-104

15. Drp 104

16. Sirpiglenastat?

17. Orb1687484

18. Chembl4650367

19. Schembl20465436

20. Schembl29495819

21. Glxc-26739

22. Ex-a10433

23. Da-67601

24. Hy-132832

25. Cs-0204139

26. D12008

27. G18545

28. Isopropyl(s)-2-((s)-2-acetamido-3-(1h-indol-3-yl)-propanamido)-6-diazo-5-oxo-hexanoate

29. Propan-2-yl (2s)-2-[[(2s)-2-acetamido-3-(1h-indol-3-yl)propanoyl]amino]-6-diazo-5-oxohexanoate

2.4 Create Date

2019-01-26

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₂₇N₅O₅
Molecular Weight	441.5 g/mol
XLogP3	1.2
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	12
Exact Mass	Da
Monoisotopic Mass	Da
Topological Polar Surface Area	119
Heavy Atom Count	32
Formal Charge	0
Complexity	749
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	1
Covalently Bonded Unit Count	1