1. (r)-n-(3-quinuclidinyl)-7-oxo-dihydrothieno(3,2b)pyridine-6-carboxamide Hydrochloride
2. Dpp-733
3. Mkc-733
1. Pumosetrag [inn]
2. 153062-94-3
3. Chembl1643880
4. 1g26b32139
5. N-((3r)-1-azabicyclo(2.2.2)oct-3-yl)-7-oxo-4,7-dihydrothieno(3,2-b)pyridine-6-carboxamide
6. Ddp 733
7. Unii-1g26b32139
8. Schembl390615
9. Ddp733
10. Zinc16869
11. Dtxsid70165211
12. Bdbm50334438
13. Db12402
14. 1055328-70-5
15. Q27252379
16. (r)-7-oxo-n-(quinuclidin-3-yl)-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamide
17. N-[(3r)-1-azabicyclo[2.2.2]octane-3-yl]-7-oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamide
18. Thieno(3,2-b)pyridine-6-carboxamide, N-(3r)-1-azabicyclo(2.2.2)oct-3-yl-4,7-dihydro-7-oxo-
19. Thieno(3,2-b)pyridine-6-carboxamide, N-1-azabicyclo(2.2.2)oct-3-yl-4,7-dihydro-7-oxo-, (r)-
| Molecular Weight | 303.4 g/mol |
|---|---|
| Molecular Formula | C15H17N3O2S |
| XLogP3 | 1.7 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 303.10414797 g/mol |
| Monoisotopic Mass | 303.10414797 g/mol |
| Topological Polar Surface Area | 89.7 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 499 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in constipation, gastroesophageal reflux disease (GERD), gastrointestinal diseases and disorders (miscellaneous), and irritable bowel syndrome (IBS).
DDP733 is an agonist of 5-HT3 receptors, a specific sub-type of serotonin receptor. Serotonin, a neurotransmitter, is believed to play an important role in the regulation of gastrointestinal motility.
