loader
Please Wait
Applying Filters...

Suanfarma Suanfarma

X
menu

    Market Place

    Market Place

    Post Enquiry

    Post Enquiry
    menu

    Technical details about Pegunigalsidase alfa, learn more about the structure, uses, toxicity, action, side effects and more

    Client Email Product
    Menu

    Pegunigalsidase alfa

    DEVELOPMENTS

    DOSSIERs // Finished Dosage Forms

    DIGITAL CONTENT

    PharmaCompass

    Inke S.A: APIs manufacturing plant.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    1. Also known as: Pegunigalsidase-alfa, Q27270744
    Molecular Formula
    C24H44N6O9
    Molecular Weight
    560.6  g/mol
    InChI Key
    CQPWQUAJPPFCDP-ROUUACIJSA-N
    Pegunigalsidase alfa is under investigation in clinical trial NCT02921620 (Study to Evaluate the Safety and EffIcacy of PRX-102 on Gastrointestinal Symptoms in Nave Fabry Disease).
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (2S)-2-amino-6-[[4-[2-[2-[[4-[[(5S)-5-amino-5-carboxypentyl]amino]-4-oxobutanoyl]amino]ethoxy]ethylamino]-4-oxobutanoyl]amino]hexanoic acid
    2.1.2 InChI
    InChI=1S/C24H44N6O9/c25-17(23(35)36)5-1-3-11-27-19(31)7-9-21(33)29-13-15-39-16-14-30-22(34)10-8-20(32)28-12-4-2-6-18(26)24(37)38/h17-18H,1-16,25-26H2,(H,27,31)(H,28,32)(H,29,33)(H,30,34)(H,35,36)(H,37,38)/t17-,18-/m0/s1
    2.1.3 InChI Key
    CQPWQUAJPPFCDP-ROUUACIJSA-N
    2.1.4 Canonical SMILES
    C(CCNC(=O)CCC(=O)NCCOCCNC(=O)CCC(=O)NCCCCC(C(=O)O)N)CC(C(=O)O)N
    2.1.5 Isomeric SMILES
    C(CCNC(=O)CCC(=O)NCCOCCNC(=O)CCC(=O)NCCCC[C@@H](C(=O)O)N)C[C@@H](C(=O)O)N
    2.2 Synonyms
    2.2.1 Depositor-Supplied Synonyms

    1. Pegunigalsidase-alfa

    2. Q27270744

    2.3 Create Date
    2016-08-16
    3 Chemical and Physical Properties
    Molecular Weight 560.6 g/mol
    Molecular Formula C24H44N6O9
    XLogP3-8
    Hydrogen Bond Donor Count8
    Hydrogen Bond Acceptor Count11
    Rotatable Bond Count24
    Exact Mass560.31697700 g/mol
    Monoisotopic Mass560.31697700 g/mol
    Topological Polar Surface Area252 Ų
    Heavy Atom Count39
    Formal Charge0
    Complexity719
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Indication

    Treatment of Fabry disease

    5 Pharmacology and Biochemistry
    5.1 ATC Code

    A - Alimentary tract and metabolism

    A16 - Other alimentary tract and metabolism products

    A16A - Other alimentary tract and metabolism products

    A16AB - Enzymes

    A16AB20 - Pegunigalsidase alfa

    Post Enquiry
    POST ENQUIRY