1. 2-(diethylamino)ethanol
2. 2-(dimethylamino)ethanol Hydrochloride
3. 2-(n,n-dimethylamino)ethanol Hydrochloride
4. 2-diethylaminoethanol Hydrochloride
5. 2-diethylaminoethanol Hydrochloride, 14c-labeled
6. 2-diethylaminoethanol Sulfate (2:1)
7. 2-diethylaminoethanol Tartrate
8. 2-diethylaminoethanol, Sodium Salt
9. Deae
10. Deanol Hydrochloride
11. Diethylaminoethanol
12. Diethylethanolamine
13. Ethanol, 2-(dimethylamino)-, Hydrochloride (1:1)
14. Ethanol, 2-dimethylamino-, Hydrochloride
15. N,n-diethylethanolamine
1. 2-(diethylamino)ethanol
2. Diethylaminoethanol
3. 100-37-8
4. N,n-diethylethanolamine
5. Diethylethanolamine
6. Deae
7. (diethylamino)ethanol
8. Ethanol, 2-(diethylamino)-
9. N,n-diethyl-2-aminoethanol
10. (2-hydroxyethyl)diethylamine
11. Diethyl(2-hydroxyethyl)amine
12. Diethylmonoethanolamine
13. 2-hydroxytriethylamine
14. Pennad 150
15. Diaethylaminoaethanol
16. 2-(diethylamino)ethan-1-ol
17. 2-(n,n-diethylamino)ethanol
18. N,n-diethylmonoethanolamine
19. N,n-diethyl-2-hydroxyethylamine
20. Beta-diethylaminoethanol
21. Beta-hydroxytriethylamine
22. 2-(diethylamino)ethyl Alcohol
23. Diethylamino Ethanol
24. N-diethylaminoethanol
25. 2-diethylamino-ethanol
26. 2-n-diethylaminoethanol
27. Diethyl Ethanolamine
28. Deea
29. Beta-diethylaminoethyl Alcohol
30. N-(diethylamino)ethanol
31. N,n-diethyl-n-(beta-hydroxyethyl)amine
32. Nsc 8759
33. N,n-diethylaminoethanol
34. 2-(diethylamino)-ethanol
35. 2-n-(diethylamino)ethanol
36. .beta.-(diethylamino)ethanol
37. Ethanol,2-diethylamino
38. S6dl4m053u
39. Beta-(diethylamino)ethyl Alcohol
40. Chebi:52153
41. .beta.-(diethylamino)ethyl Alcohol
42. Nsc-8759
43. N,n-diethyl-n-(.beta.-hydroxyethyl)amine
44. Dsstox_cid_1837
45. Dsstox_rid_76358
46. Dsstox_gsid_21837
47. Cas-100-37-8
48. Diaethylaminoaethanol [german]
49. Ccris 4793
50. Hsdb 329
51. Einecs 202-845-2
52. Un2686
53. Unii-s6dl4m053u
54. Ai3-16309
55. 2-diethylamino
56. Diathylaminoathanol
57. Diethylamlnoethanol
58. Mfcd00002850
59. N,n-diethyl Ethanolamine
60. N, N-diethylethanolamine
61. Beta-(diethylamino)ethanol
62. N,n-diethyl Ethanol Amine
63. 2-diethylaminoethanol [un2686] [corrosive]
64. .beta.-hydroxytriethylamine
65. Ec 202-845-2
66. Schembl3114
67. 2-diethylaminoethanol, 9ci
68. Chembl1183
69. Diaethylaminoaethanol(german)
70. 2-(diethylamino)-1-ethanol
71. Mls002174251
72. 2-(n,n-diethylamino)-ethanol
73. 2-(diethylamino)ethanol, 99%
74. Dtxsid5021837
75. Diethylaminoethanol [hsdb]
76. N-(beta-hydroxyethyl)diethylamine
77. Nsc8759
78. Hms3039i08
79. Zinc388479
80. 2-(diethylamino)ethanol, >=99%
81. Diethyl Ethanolamine [inci]
82. Diethylaminoethanol [mart.]
83. Wln: Q2n2 & 2
84. Adal1185323
85. Diethylaminoethanol [who-dd]
86. N-(hydroxyethyl)-n,n-diethyl Amine
87. Tox21_201463
88. Tox21_300037
89. Bbl012211
90. Stl163552
91. 2-(diethylamino)ethanol [mi]
92. 2-(diethylamino)ethanol, >=99.5%
93. Akos000119883
94. Un 2686
95. Ncgc00090925-01
96. Ncgc00090925-02
97. Ncgc00090925-03
98. Ncgc00253920-01
99. Ncgc00259014-01
100. A 22
101. Bp-20552
102. Smr001261425
103. Vs-03234
104. Db-012722
105. D0465
106. 2-diethylaminoethanol [un2686] [corrosive]
107. D88192
108. 2-(diethylamino)ethanol, Purum, >=99.0% (gc)
109. Q209373
110. 2-diethylaminoethanol 100 Microg/ml In Acetonitrile
111. J-520312
112. Diethyl Ethanolamine Diethylaminoethanol 2-hydroxytriethylamine
Molecular Weight | 117.19 g/mol |
---|---|
Molecular Formula | C6H15NO |
XLogP3 | 0.3 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 4 |
Exact Mass | 117.115364102 g/mol |
Monoisotopic Mass | 117.115364102 g/mol |
Topological Polar Surface Area | 23.5 Ų |
Heavy Atom Count | 8 |
Formal Charge | 0 |
Complexity | 43.8 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
ORALLY ADMIN TO RATS, WAS MAINLY EXCRETED VIA KIDNEYS. ELIMINATED WITHIN FIRST 24 HR. AFTER 48 HR EXCRETED INDEPENDENTLY OF DOSE. AFTER 40 DAYS STILL BEING ELIMINATED. UP TO 60% ACCUMULATED IN LIVER. CNS & SPINAL CORD SHOWED HIGHEST CONCN AFTER 7 DAYS.
SCHULTE KE ET AL; ARZNEIM- FORSCH 22 (8): 1381 (1972)
The absorption of 2-diethylaminoethanol (administered orally as 2-diethylaminoethanol acid malate or 'Cerebrol') in healthy adult rats is very rapid, reaching a peak plasma level in 30 min. The biological half-life is 3.5 hr with 39% of the excreted product appearing in the urine after 48 hr.
Snyder, R. (ed.). Ethel Browning's Toxicity and Metabolism of Industrial Solvents. 2nd ed. Volume II: Nitrogen and Phosphorus Solvents. Amsterdam-New York-Oxford: Elsevier, 1990., p. 412
CHRONIC ORAL ADMIN ... TO RATS RESULTS IN LIVER ACCUM OF UP TO 60% OF THE DRUG. ... METABOLITES PRODUCED WERE DIETHYLAMINOETHANOL N-OXIDE, DIETHYLAMINOACETIC ACID & ETHYLAMINOETHANOL ... .
The Chemical Society. Foreign Compound Metabolism in Mammals Volume 3. London: The Chemical Society, 1975., p. 272
The biological half-life is 3.5 hr ... .
Snyder, R. (ed.). Ethel Browning's Toxicity and Metabolism of Industrial Solvents. 2nd ed. Volume II: Nitrogen and Phosphorus Solvents. Amsterdam-New York-Oxford: Elsevier, 1990., p. 413