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Chemistry

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Also known as: 2-(diethylamino)ethanol, Diethylaminoethanol, 100-37-8, N,n-diethylethanolamine, Diethylethanolamine, Deae
Molecular Formula
C6H15NO
Molecular Weight
117.19  g/mol
InChI Key
BFSVOASYOCHEOV-UHFFFAOYSA-N
FDA UNII
S6DL4M053U

Mesitylene
1 2D Structure

Mesitylene

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(diethylamino)ethanol
2.1.2 InChI
InChI=1S/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H3
2.1.3 InChI Key
BFSVOASYOCHEOV-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCN(CC)CCO
2.2 Other Identifiers
2.2.1 UNII
S6DL4M053U
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(diethylamino)ethanol

2. 2-(dimethylamino)ethanol Hydrochloride

3. 2-(n,n-dimethylamino)ethanol Hydrochloride

4. 2-diethylaminoethanol Hydrochloride

5. 2-diethylaminoethanol Hydrochloride, 14c-labeled

6. 2-diethylaminoethanol Sulfate (2:1)

7. 2-diethylaminoethanol Tartrate

8. 2-diethylaminoethanol, Sodium Salt

9. Deae

10. Deanol Hydrochloride

11. Diethylaminoethanol

12. Diethylethanolamine

13. Ethanol, 2-(dimethylamino)-, Hydrochloride (1:1)

14. Ethanol, 2-dimethylamino-, Hydrochloride

15. N,n-diethylethanolamine

2.3.2 Depositor-Supplied Synonyms

1. 2-(diethylamino)ethanol

2. Diethylaminoethanol

3. 100-37-8

4. N,n-diethylethanolamine

5. Diethylethanolamine

6. Deae

7. (diethylamino)ethanol

8. Ethanol, 2-(diethylamino)-

9. N,n-diethyl-2-aminoethanol

10. (2-hydroxyethyl)diethylamine

11. Diethyl(2-hydroxyethyl)amine

12. Diethylmonoethanolamine

13. 2-hydroxytriethylamine

14. Pennad 150

15. Diaethylaminoaethanol

16. 2-(diethylamino)ethan-1-ol

17. 2-(n,n-diethylamino)ethanol

18. N,n-diethylmonoethanolamine

19. N,n-diethyl-2-hydroxyethylamine

20. Beta-diethylaminoethanol

21. Beta-hydroxytriethylamine

22. 2-(diethylamino)ethyl Alcohol

23. Diethylamino Ethanol

24. N-diethylaminoethanol

25. 2-diethylamino-ethanol

26. 2-n-diethylaminoethanol

27. Diethyl Ethanolamine

28. Deea

29. Beta-diethylaminoethyl Alcohol

30. N-(diethylamino)ethanol

31. N,n-diethyl-n-(beta-hydroxyethyl)amine

32. Nsc 8759

33. N,n-diethylaminoethanol

34. 2-(diethylamino)-ethanol

35. 2-n-(diethylamino)ethanol

36. .beta.-(diethylamino)ethanol

37. Ethanol,2-diethylamino

38. S6dl4m053u

39. Beta-(diethylamino)ethyl Alcohol

40. Chebi:52153

41. .beta.-(diethylamino)ethyl Alcohol

42. Nsc-8759

43. N,n-diethyl-n-(.beta.-hydroxyethyl)amine

44. Dsstox_cid_1837

45. Dsstox_rid_76358

46. Dsstox_gsid_21837

47. Cas-100-37-8

48. Diaethylaminoaethanol [german]

49. Ccris 4793

50. Hsdb 329

51. Einecs 202-845-2

52. Un2686

53. Unii-s6dl4m053u

54. Ai3-16309

55. 2-diethylamino

56. Diathylaminoathanol

57. Diethylamlnoethanol

58. Mfcd00002850

59. N,n-diethyl Ethanolamine

60. N, N-diethylethanolamine

61. Beta-(diethylamino)ethanol

62. N,n-diethyl Ethanol Amine

63. 2-diethylaminoethanol [un2686] [corrosive]

64. .beta.-hydroxytriethylamine

65. Ec 202-845-2

66. Schembl3114

67. 2-diethylaminoethanol, 9ci

68. Chembl1183

69. Diaethylaminoaethanol(german)

70. 2-(diethylamino)-1-ethanol

71. Mls002174251

72. 2-(n,n-diethylamino)-ethanol

73. 2-(diethylamino)ethanol, 99%

74. Dtxsid5021837

75. Diethylaminoethanol [hsdb]

76. N-(beta-hydroxyethyl)diethylamine

77. Nsc8759

78. Hms3039i08

79. Zinc388479

80. 2-(diethylamino)ethanol, >=99%

81. Diethyl Ethanolamine [inci]

82. Diethylaminoethanol [mart.]

83. Wln: Q2n2 & 2

84. Adal1185323

85. Diethylaminoethanol [who-dd]

86. N-(hydroxyethyl)-n,n-diethyl Amine

87. Tox21_201463

88. Tox21_300037

89. Bbl012211

90. Stl163552

91. 2-(diethylamino)ethanol [mi]

92. 2-(diethylamino)ethanol, >=99.5%

93. Akos000119883

94. Un 2686

95. Ncgc00090925-01

96. Ncgc00090925-02

97. Ncgc00090925-03

98. Ncgc00253920-01

99. Ncgc00259014-01

100. A 22

101. Bp-20552

102. Smr001261425

103. Vs-03234

104. Db-012722

105. D0465

106. 2-diethylaminoethanol [un2686] [corrosive]

107. D88192

108. 2-(diethylamino)ethanol, Purum, >=99.0% (gc)

109. Q209373

110. 2-diethylaminoethanol 100 Microg/ml In Acetonitrile

111. J-520312

112. Diethyl Ethanolamine Diethylaminoethanol 2-hydroxytriethylamine

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 117.19 g/mol
Molecular Formula C6H15NO
XLogP30.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass117.115364102 g/mol
Monoisotopic Mass117.115364102 g/mol
Topological Polar Surface Area23.5 Ų
Heavy Atom Count8
Formal Charge0
Complexity43.8
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


4.2 Absorption, Distribution and Excretion

ORALLY ADMIN TO RATS, WAS MAINLY EXCRETED VIA KIDNEYS. ELIMINATED WITHIN FIRST 24 HR. AFTER 48 HR EXCRETED INDEPENDENTLY OF DOSE. AFTER 40 DAYS STILL BEING ELIMINATED. UP TO 60% ACCUMULATED IN LIVER. CNS & SPINAL CORD SHOWED HIGHEST CONCN AFTER 7 DAYS.

SCHULTE KE ET AL; ARZNEIM- FORSCH 22 (8): 1381 (1972)


The absorption of 2-diethylaminoethanol (administered orally as 2-diethylaminoethanol acid malate or 'Cerebrol') in healthy adult rats is very rapid, reaching a peak plasma level in 30 min. The biological half-life is 3.5 hr with 39% of the excreted product appearing in the urine after 48 hr.

Snyder, R. (ed.). Ethel Browning's Toxicity and Metabolism of Industrial Solvents. 2nd ed. Volume II: Nitrogen and Phosphorus Solvents. Amsterdam-New York-Oxford: Elsevier, 1990., p. 412


4.3 Metabolism/Metabolites

CHRONIC ORAL ADMIN ... TO RATS RESULTS IN LIVER ACCUM OF UP TO 60% OF THE DRUG. ... METABOLITES PRODUCED WERE DIETHYLAMINOETHANOL N-OXIDE, DIETHYLAMINOACETIC ACID & ETHYLAMINOETHANOL ... .

The Chemical Society. Foreign Compound Metabolism in Mammals Volume 3. London: The Chemical Society, 1975., p. 272


4.4 Biological Half-Life

The biological half-life is 3.5 hr ... .

Snyder, R. (ed.). Ethel Browning's Toxicity and Metabolism of Industrial Solvents. 2nd ed. Volume II: Nitrogen and Phosphorus Solvents. Amsterdam-New York-Oxford: Elsevier, 1990., p. 413


ABOUT THIS PAGE

Looking for 100-37-8 / Mesitylene API manufacturers, exporters & distributors?

Mesitylene manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Mesitylene API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Mesitylene manufacturer or Mesitylene supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Mesitylene manufacturer or Mesitylene supplier.

PharmaCompass also assists you with knowing the Mesitylene API Price utilized in the formulation of products. Mesitylene API Price is not always fixed or binding as the Mesitylene Price is obtained through a variety of data sources. The Mesitylene Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Mesitylene

Synonyms

2-(diethylamino)ethanol, Diethylaminoethanol, 100-37-8, N,n-diethylethanolamine, Diethylethanolamine, Deae

Cas Number

100-37-8

Unique Ingredient Identifier (UNII)

S6DL4M053U

Mesitylene Manufacturers

A Mesitylene manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mesitylene, including repackagers and relabelers. The FDA regulates Mesitylene manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mesitylene API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Mesitylene Suppliers

A Mesitylene supplier is an individual or a company that provides Mesitylene active pharmaceutical ingredient (API) or Mesitylene finished formulations upon request. The Mesitylene suppliers may include Mesitylene API manufacturers, exporters, distributors and traders.

Mesitylene GMP

Mesitylene Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Mesitylene GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Mesitylene GMP manufacturer or Mesitylene GMP API supplier for your needs.

Mesitylene CoA

A Mesitylene CoA (Certificate of Analysis) is a formal document that attests to Mesitylene's compliance with Mesitylene specifications and serves as a tool for batch-level quality control.

Mesitylene CoA mostly includes findings from lab analyses of a specific batch. For each Mesitylene CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Mesitylene may be tested according to a variety of international standards, such as European Pharmacopoeia (Mesitylene EP), Mesitylene JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Mesitylene USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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