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2D Structure
Also known as: Colestipol hydrochloride
Molecular Formula
C8H24ClN5
Molecular Weight
225.76  g/mol
InChI Key
GACQNVJDWUAPFY-UHFFFAOYSA-N

Highly crosslinked and insoluble basic anion exchange resin used as anticholesteremic. It may also may reduce triglyceride levels.
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N'-[2-[2-(2-aminoethylamino)ethylamino]ethyl]ethane-1,2-diamine;hydron;chloride
2.1.2 InChI
InChI=1S/C8H23N5.ClH/c9-1-3-11-5-7-13-8-6-12-4-2-10;/h11-13H,1-10H2;1H
2.1.3 InChI Key
GACQNVJDWUAPFY-UHFFFAOYSA-N
2.1.4 Canonical SMILES
[H+].C(CNCCNCCNCCN)N.[Cl-]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Colestid

2. Colestipol

3. Colestipol Hcl

4. Colestipol Hydrochloride

5. Hcl, Colestipol

6. Hydrochloride, Colestipol

7. U 26,597 A

8. U-26,597 A

9. U26,597 A

2.2.2 Depositor-Supplied Synonyms

1. Colestipol Hydrochloride

2.3 Create Date
2015-11-07
3 Chemical and Physical Properties
Molecular Weight 225.76 g/mol
Molecular Formula C8H24ClN5
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count6
Rotatable Bond Count10
Exact Mass225.1720235 g/mol
Monoisotopic Mass225.1720235 g/mol
Topological Polar Surface Area88.1 Ų
Heavy Atom Count14
Formal Charge0
Complexity78.6
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anion Exchange Resins

High-molecular-weight insoluble polymers that contain functional cationic groups capable of undergoing exchange reactions with anions. (See all compounds classified as Anion Exchange Resins.)


Hypolipidemic Agents

Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. (See all compounds classified as Hypolipidemic Agents.)


Sequestering Agents

Compounds that bind to and reduce the biological availability of a chemical or pharmaceutical agent. (See all compounds classified as Sequestering Agents.)


4.2 FDA Pharmacological Classification
4.2.1 Pharmacological Classes
Bile-acid Binding Activity [MoA]; Bile Acid Sequestrant [EPC]