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Technical details about Glycolide - lactide copolymer, learn more about the structure, uses, toxicity, action, side effects and more

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2D Structure
1. Also known as: 26780-50-7, Poly(d,l-lactide-co-glycolide), Polyglactin, Poly(dl-lactide-co-glycolide), 3,6-dimethyl-1,4-dioxane-2,5-dione;1,4-dioxane-2,5-dione, Vicryl (tn)
Molecular Formula
C10H12O8
Molecular Weight
260.20  g/mol
InChI Key
LCSKNASZPVZHEG-UHFFFAOYSA-N

A polyester used for absorbable sutures and surgical mesh, especially in ophthalmic surgery. 2-Hydroxy-propanoic acid polymer with polymerized hydroxyacetic acid, which forms 3,6-dimethyl-1,4-dioxane-dione polymer with 1,4-dioxane-2,5-dione copolymer of molecular weight about 80,000 daltons.
1 2D Structure

2D Structure

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3,6-dimethyl-1,4-dioxane-2,5-dione;1,4-dioxane-2,5-dione
2.1.2 InChI
InChI=1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2
2.1.3 InChI Key
LCSKNASZPVZHEG-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1C(=O)OC(C(=O)O1)C.C1C(=O)OCC(=O)O1
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Acid Polyester, Glycolic-lactic

2. Dimethyldioxanedione Polymer With Dioxanedione Polymer

3. Dioxanedione Polymer With Dimethyldioxanedione Polymer

4. Glycolic Lactic Acid Polyester

5. Glycolic-lactic Acid Polyester

6. Poly(glycolide Lactide)copolymer

7. Poly(lactide-co-glycolide)

8. Poly(lactide-co-glycoside)

9. Polyester, Glycolic-lactic Acid

10. Polygalactin 910

11. Polyglactin

12. Polyglactin 910

2.2.2 Depositor-Supplied Synonyms

1. 26780-50-7

2. Poly(d,l-lactide-co-glycolide)

3. Polyglactin

4. Poly(dl-lactide-co-glycolide)

5. 3,6-dimethyl-1,4-dioxane-2,5-dione;1,4-dioxane-2,5-dione

6. Vicryl (tn)

7. Plga Lactide Glycolide

8. Polyglactin 370 (usan)

9. Polyglactin 910 (usan)

10. Schembl631659

11. Plga Lactide Glycolide 75:25

12. Dtxsid80910517

13. Poly (d,l-lactide-co-glycolide)

14. D05556

15. D06487

16. 1,4-dioxane-2,5-dione--3,6-dimethyl-1,4-dioxane-2,5-dione (1/1)

17. 107760-14-5

2.3 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 260.20 g/mol
Molecular Formula C10H12O8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count0
Exact Mass260.05321734 g/mol
Monoisotopic Mass260.05321734 g/mol
Topological Polar Surface Area105 Ų
Heavy Atom Count18
Formal Charge0
Complexity267
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
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