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    Technical details about Ginsenoside Rg1, learn more about the structure, uses, toxicity, action, side effects and more

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    Ginsenoside Rg1

    ANALYTICAL SOLUTION(s)

    PharmaCompass

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    2D Structure
    1. Also known as: 22427-39-0, Sanchinoside c1, Panaxoside a, Ginsenoside a2, Panaxoside rg1, Sanchinoside rg1
    Molecular Formula
    C42H72O14
    Molecular Weight
    801.0  g/mol
    InChI Key
    YURJSTAIMNSZAE-HHNZYBFYSA-N
    FDA UNII
    PJ788634QY
    ginsenoside rg1 is a natural product found in Panax vietnamensis, Panax ginseng, and Panax notoginseng with data available.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
    2.1.2 InChI
    InChI=1S/C42H72O14/c1-20(2)10-9-13-42(8,56-37-34(52)32(50)30(48)25(19-44)55-37)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36+,37-,39+,40+,41+,42-/m0/s1
    2.1.3 InChI Key
    YURJSTAIMNSZAE-HHNZYBFYSA-N
    2.1.4 Canonical SMILES
    CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)O)C)O)C)OC6C(C(C(C(O6)CO)O)O)O)C
    2.1.5 Isomeric SMILES
    CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(C[C@@H]([C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)O)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C
    2.2 Other Identifiers
    2.2.1 UNII
    PJ788634QY
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Ginsenoside-rg(1)

    2. Panaxoside Rg1

    3. Sanchinoside C(1)

    4. Sanchinoside C1

    2.3.2 Depositor-Supplied Synonyms

    1. 22427-39-0

    2. Sanchinoside C1

    3. Panaxoside A

    4. Ginsenoside A2

    5. Panaxoside Rg1

    6. Sanchinoside Rg1

    7. (3beta,6alpha,12beta)-3,12-dihydroxydammar-24-ene-6,20-diyl Bis-beta-d-glucopyranoside

    8. (20s)-ginsenoside Rg1

    9. Ginsenoside-rg1

    10. Chebi:67987

    11. Pj788634qy

    12. Ginsenoside G1

    13. Mfcd00210293

    14. Chembl501637

    15. Unii-pj788634qy

    16. Ginsenosiderg1

    17. Einecs 244-989-9

    18. Bidd:er0075

    19. Dammarane, -d-glucopyranoside

    20. Schembl19875635

    21. Dtxsid70945111

    22. Ginsenoside Rg1 [usp-rs]

    23. Ginsenoside Rg1 [who-dd]

    24. Hms3885m12

    25. Ex-a6784

    26. Hy-n0045

    27. Rg1

    28. 6-(hexopyranosyloxy)-3,12-dihydroxydammar-24-en-20-yl Hexopyranoside

    29. Ginsenoside Rg1, Analytical Standard

    30. S3923

    31. (6)-beta-d-glucopyranosyl-(20)-beta-d-glucopyranosyl-20s-protopanaxatriol

    32. Akos037514672

    33. Zinc238809655

    34. Ccg-270492

    35. Cs-3832

    36. Db06750

    37. Bs-16671

    38. G0533

    39. N1613

    40. C08946

    41. 427g390

    42. A816192

    43. Q-100285

    44. Q2276594

    45. 7-hydroxy-2-oxo-2h-chromene-3-carboxylicacidamide

    46. Ginsenoside Rg1, Primary Pharmaceutical Reference Standard

    47. Ginsenoside Rg1, United States Pharmacopeia (usp) Reference Standard

    48. (3b,6a,12b)-3,12-dihydroxydammar-24-ene-6,20- Diylbis(beta-d-glucopyranoside)

    49. (3beta,6alpha,12beta)-3,12-dihydroxydammar-24-ene-6,20-diylbis(beta-d-glucopyranoside)

    50. (6)-.beta.-d-glucopyranosyl-(20)-.beta.-d-glucopyranosyl-20s- Protopanaxatriol

    51. Beta-d-glucopyranoside, (3beta,6alpha,12beta)-3,12-dihydroxy Dammar-24-ene-6,20-diylbis-

    52. Beta-d-glucopyranoside, (3beta,6alpha,12beta)-3,12-dihydroxydammar-24-ene-6,20-diyl Bis-

    53. (2r,3r,4s,5s,6r)-2-(((3s,5r,6s,8r,9r,10r,12r,13r,14r,17s)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-((s)-6-methyl-2-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1h-cyclopenta[a]phenanthren-6-yl)oxy)-6-(hydroxymethyl)tetrahydro-2h-pyran-3,4,5-triol

    54. (3.beta.,6.alpha.,12.beta.)-3,12-dihydroxydammar-24-ene-6,20- Diylbis(.beta.-d-glucopyranoside)

    55. (3beta,alpha,12beta)-20-(beta-d-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl Beta-d-glucopyranoside

    56. .beta.-d-glucopyranoside, (3.beta.,6.alpha.,12.beta.)-3,12- Dihydroxy Dammar-24-ene-6,20-diylbis-

    57. .beta.-d-glucopyranoside, (3.beta.,6.alpha.,12.beta.)-3,12-dihydroxydammar-24-ene-6,20-diyl Bis-

    58. Ginsenoside Rg1 (constituent Of American Ginseng, Asian Ginseng, And Tienchi Ginseng) [dsc]

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 801.0 g/mol
    Molecular Formula C42H72O14
    XLogP32.7
    Hydrogen Bond Donor Count10
    Hydrogen Bond Acceptor Count14
    Rotatable Bond Count10
    Exact Mass800.49220697 g/mol
    Monoisotopic Mass800.49220697 g/mol
    Topological Polar Surface Area239 Ų
    Heavy Atom Count56
    Formal Charge0
    Complexity1410
    Isotope Atom Count0
    Defined Atom Stereocenter Count21
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Central Nervous System Agents

    A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252) (See all compounds classified as Central Nervous System Agents.)

    4.2 Metabolism/Metabolites

    M1 (20- O -- D -glucopyranosyl-20( S )- protopanaxadiol ) is a ppd-type monoglucoside ginsenoside metabolized by intestinal bacteria in humans

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