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Chemistry

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Also known as: 22427-39-0, Sanchinoside c1, Panaxoside a, Ginsenoside a2, Panaxoside rg1, Sanchinoside rg1
Molecular Formula
C42H72O14
Molecular Weight
801.0  g/mol
InChI Key
YURJSTAIMNSZAE-HHNZYBFYSA-N
FDA UNII
PJ788634QY

Ginsenoside Rg1
ginsenoside rg1 is a natural product found in Panax vietnamensis, Panax ginseng, and Panax notoginseng with data available.
1 2D Structure

Ginsenoside Rg1

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
2.1.2 InChI
InChI=1S/C42H72O14/c1-20(2)10-9-13-42(8,56-37-34(52)32(50)30(48)25(19-44)55-37)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36+,37-,39+,40+,41+,42-/m0/s1
2.1.3 InChI Key
YURJSTAIMNSZAE-HHNZYBFYSA-N
2.1.4 Canonical SMILES
CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)O)C)O)C)OC6C(C(C(C(O6)CO)O)O)O)C
2.1.5 Isomeric SMILES
CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(C[C@@H]([C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)O)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C
2.2 Other Identifiers
2.2.1 UNII
PJ788634QY
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ginsenoside-rg(1)

2. Panaxoside Rg1

3. Sanchinoside C(1)

4. Sanchinoside C1

2.3.2 Depositor-Supplied Synonyms

1. 22427-39-0

2. Sanchinoside C1

3. Panaxoside A

4. Ginsenoside A2

5. Panaxoside Rg1

6. Sanchinoside Rg1

7. (3beta,6alpha,12beta)-3,12-dihydroxydammar-24-ene-6,20-diyl Bis-beta-d-glucopyranoside

8. (20s)-ginsenoside Rg1

9. Ginsenoside-rg1

10. Chebi:67987

11. Pj788634qy

12. Ginsenoside G1

13. Mfcd00210293

14. Chembl501637

15. Unii-pj788634qy

16. Ginsenosiderg1

17. Einecs 244-989-9

18. Bidd:er0075

19. Dammarane, -d-glucopyranoside

20. Schembl19875635

21. Dtxsid70945111

22. Ginsenoside Rg1 [usp-rs]

23. Ginsenoside Rg1 [who-dd]

24. Hms3885m12

25. Ex-a6784

26. Hy-n0045

27. Rg1

28. 6-(hexopyranosyloxy)-3,12-dihydroxydammar-24-en-20-yl Hexopyranoside

29. Ginsenoside Rg1, Analytical Standard

30. S3923

31. (6)-beta-d-glucopyranosyl-(20)-beta-d-glucopyranosyl-20s-protopanaxatriol

32. Akos037514672

33. Zinc238809655

34. Ccg-270492

35. Cs-3832

36. Db06750

37. Bs-16671

38. G0533

39. N1613

40. C08946

41. 427g390

42. A816192

43. Q-100285

44. Q2276594

45. 7-hydroxy-2-oxo-2h-chromene-3-carboxylicacidamide

46. Ginsenoside Rg1, Primary Pharmaceutical Reference Standard

47. Ginsenoside Rg1, United States Pharmacopeia (usp) Reference Standard

48. (3b,6a,12b)-3,12-dihydroxydammar-24-ene-6,20- Diylbis(beta-d-glucopyranoside)

49. (3beta,6alpha,12beta)-3,12-dihydroxydammar-24-ene-6,20-diylbis(beta-d-glucopyranoside)

50. (6)-.beta.-d-glucopyranosyl-(20)-.beta.-d-glucopyranosyl-20s- Protopanaxatriol

51. Beta-d-glucopyranoside, (3beta,6alpha,12beta)-3,12-dihydroxy Dammar-24-ene-6,20-diylbis-

52. Beta-d-glucopyranoside, (3beta,6alpha,12beta)-3,12-dihydroxydammar-24-ene-6,20-diyl Bis-

53. (2r,3r,4s,5s,6r)-2-(((3s,5r,6s,8r,9r,10r,12r,13r,14r,17s)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-((s)-6-methyl-2-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1h-cyclopenta[a]phenanthren-6-yl)oxy)-6-(hydroxymethyl)tetrahydro-2h-pyran-3,4,5-triol

54. (3.beta.,6.alpha.,12.beta.)-3,12-dihydroxydammar-24-ene-6,20- Diylbis(.beta.-d-glucopyranoside)

55. (3beta,alpha,12beta)-20-(beta-d-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl Beta-d-glucopyranoside

56. .beta.-d-glucopyranoside, (3.beta.,6.alpha.,12.beta.)-3,12- Dihydroxy Dammar-24-ene-6,20-diylbis-

57. .beta.-d-glucopyranoside, (3.beta.,6.alpha.,12.beta.)-3,12-dihydroxydammar-24-ene-6,20-diyl Bis-

58. Ginsenoside Rg1 (constituent Of American Ginseng, Asian Ginseng, And Tienchi Ginseng) [dsc]

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 801.0 g/mol
Molecular Formula C42H72O14
XLogP32.7
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count14
Rotatable Bond Count10
Exact Mass800.49220697 g/mol
Monoisotopic Mass800.49220697 g/mol
Topological Polar Surface Area239 Ų
Heavy Atom Count56
Formal Charge0
Complexity1410
Isotope Atom Count0
Defined Atom Stereocenter Count21
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Central Nervous System Agents

A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252) (See all compounds classified as Central Nervous System Agents.)


4.2 Metabolism/Metabolites

M1 (20- O -- D -glucopyranosyl-20( S )- protopanaxadiol ) is a ppd-type monoglucoside ginsenoside metabolized by intestinal bacteria in humans


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ABOUT THIS PAGE

Looking for 22427-39-0 / Ginsenoside Rg1 API manufacturers, exporters & distributors?

Ginsenoside Rg1 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Ginsenoside Rg1 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ginsenoside Rg1 manufacturer or Ginsenoside Rg1 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ginsenoside Rg1 manufacturer or Ginsenoside Rg1 supplier.

PharmaCompass also assists you with knowing the Ginsenoside Rg1 API Price utilized in the formulation of products. Ginsenoside Rg1 API Price is not always fixed or binding as the Ginsenoside Rg1 Price is obtained through a variety of data sources. The Ginsenoside Rg1 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ginsenoside Rg1

Synonyms

22427-39-0, Sanchinoside c1, Panaxoside a, Ginsenoside a2, Panaxoside rg1, Sanchinoside rg1

Cas Number

22427-39-0

Unique Ingredient Identifier (UNII)

PJ788634QY

About Ginsenoside Rg1

ginsenoside rg1 is a natural product found in Panax vietnamensis, Panax ginseng, and Panax notoginseng with data available.

Ginsenoside Rg1 Manufacturers

A Ginsenoside Rg1 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ginsenoside Rg1, including repackagers and relabelers. The FDA regulates Ginsenoside Rg1 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ginsenoside Rg1 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ginsenoside Rg1 Suppliers

A Ginsenoside Rg1 supplier is an individual or a company that provides Ginsenoside Rg1 active pharmaceutical ingredient (API) or Ginsenoside Rg1 finished formulations upon request. The Ginsenoside Rg1 suppliers may include Ginsenoside Rg1 API manufacturers, exporters, distributors and traders.

Ginsenoside Rg1 GMP

Ginsenoside Rg1 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ginsenoside Rg1 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ginsenoside Rg1 GMP manufacturer or Ginsenoside Rg1 GMP API supplier for your needs.

Ginsenoside Rg1 CoA

A Ginsenoside Rg1 CoA (Certificate of Analysis) is a formal document that attests to Ginsenoside Rg1's compliance with Ginsenoside Rg1 specifications and serves as a tool for batch-level quality control.

Ginsenoside Rg1 CoA mostly includes findings from lab analyses of a specific batch. For each Ginsenoside Rg1 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ginsenoside Rg1 may be tested according to a variety of international standards, such as European Pharmacopoeia (Ginsenoside Rg1 EP), Ginsenoside Rg1 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ginsenoside Rg1 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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