loader
Please Wait
Applying Filters...

Suanfarma Suanfarma

X
menu

    Market Place

    Market Place

    Post Enquiry

    Post Enquiry
    menu

    Technical details about Gepotidacin, learn more about the structure, uses, toxicity, action, side effects and more

    Client Email Product
    Menu

    Gepotidacin

    DEVELOPMENTS

    PRICE INFORMATION

    INTERMEDIATES

    MARKET PLACE

    DIGITAL CONTENT

    PharmaCompass

    Inke S.A: APIs manufacturing plant.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    1. Also known as: 1075236-89-3, Gsk2140944, Gsk-2140944, Gsk 2140944, Dvf0pr037d, 3h,8h-2a,5,8a-triazaacenaphthylene-3,8-dione, 2-((4-(((3,4-dihydro-2h-pyrano(2,3-c)pyridin-6-yl)methyl)amino)-1-piperidinyl)methyl)-1,2-dihydro-, (2r)-
    Molecular Formula
    C24H28N6O3
    Molecular Weight
    448.5  g/mol
    InChI Key
    PZFAZQUREQIODZ-LJQANCHMSA-N
    FDA UNII
    DVF0PR037D
    Gepotidacin has been used in trials studying the treatment of Gonorrhea, Infections, Bacterial, and Infections, Respiratory Tract.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (3R)-3-[[4-(3,4-dihydro-2H-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.04,12]dodeca-6,8(12),9-triene-5,11-dione
    2.1.2 InChI
    InChI=1S/C24H28N6O3/c31-22-4-3-20-24-29(22)15-19(30(24)23(32)13-27-20)14-28-7-5-17(6-8-28)25-11-18-10-16-2-1-9-33-21(16)12-26-18/h3-4,10,12-13,17,19,25H,1-2,5-9,11,14-15H2/t19-/m1/s1
    2.1.3 InChI Key
    PZFAZQUREQIODZ-LJQANCHMSA-N
    2.1.4 Canonical SMILES
    C1CC2=CC(=NC=C2OC1)CNC3CCN(CC3)CC4CN5C(=O)C=CC6=C5N4C(=O)C=N6
    2.1.5 Isomeric SMILES
    C1CC2=CC(=NC=C2OC1)CNC3CCN(CC3)C[C@@H]4CN5C(=O)C=CC6=C5N4C(=O)C=N6
    2.2 Other Identifiers
    2.2.1 UNII
    DVF0PR037D
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Gsk2140944

    2.3.2 Depositor-Supplied Synonyms

    1. 1075236-89-3

    2. Gsk2140944

    3. Gsk-2140944

    4. Gsk 2140944

    5. Dvf0pr037d

    6. 3h,8h-2a,5,8a-triazaacenaphthylene-3,8-dione, 2-((4-(((3,4-dihydro-2h-pyrano(2,3-c)pyridin-6-yl)methyl)amino)-1-piperidinyl)methyl)-1,2-dihydro-, (2r)-

    7. (2r)-2-[(4-{[(3,4-dihydro-2h-pyrano[2,3-c]pyridin- 6-yl)methyl]amino}piperidin-1-yl)methyl]-1,2-dihydro- 3h,8h-2a,5,8a-triazaacenaphthylene-3,8-dione

    8. (3~{r})-3-[[4-(3,4-dihydro-2~{h}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione

    9. (3r)-3-[[4-(3,4-dihydro-2h-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.04,12]dodeca-6,8(12),9-triene-5,11-dione

    10. Gepotidacin [usan:inn]

    11. Unii-dvf0pr037d

    12. 3h,8h-2a,5,8a-triazaacenaphthylene-3,8-dione, 2-[[4-[[(3,4-dihydro-2h-pyrano[2,3-c]pyridin-6-yl)methyl]amino]-1-piperidinyl]methyl]-1,2-dihydro-, (2r)-

    13. Jhn

    14. Gepotidacin [inn]

    15. Gepotidacin (usan/inn)

    16. Gepotidacin [usan]

    17. Gepotidacin [who-dd]

    18. Schembl3332319

    19. Chembl3317856

    20. Gtpl10817

    21. Dtxsid501028208

    22. Bdbm50050549

    23. Gsk 2140944e

    24. Cs-6531

    25. Db12134

    26. Hy-16742

    27. D10878

    28. A857306

    29. Q19597285

    2.4 Create Date
    2008-12-15
    3 Chemical and Physical Properties
    Molecular Weight 448.5 g/mol
    Molecular Formula C24H28N6O3
    XLogP30.1
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count7
    Rotatable Bond Count5
    Exact Mass448.22228878 g/mol
    Monoisotopic Mass448.22228878 g/mol
    Topological Polar Surface Area90.4 Ų
    Heavy Atom Count33
    Formal Charge0
    Complexity893
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Indication

    Treatment of uncomplicated urogenital gonorrhea

    Treatment of uncomplicated urinary tract infections

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Topoisomerase Inhibitors

    Compounds that inhibit the activity of DNA TOPOISOMERASES. (See all compounds classified as Topoisomerase Inhibitors.)

    Post Enquiry
    POST ENQUIRY