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    Eltoprazine

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    INTERMEDIATES

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    2D Structure
    Also known as: 98224-03-4, 98206-09-8, 1-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazine, 1-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazine, Eltoprazine [inn], 1-(1,4-benzodioxan-5-yl)piperazine
    Molecular Formula
    C12H16N2O2
    Molecular Weight
    220.27  g/mol
    InChI Key
    WVLHGCRWEHCIOT-UHFFFAOYSA-N
    FDA UNII
    510M006KO6
    Eltoprazine has been used in trials studying the treatment of Schizophrenia and Cognitive Impairment.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine
    2.1.2 InChI
    InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2
    2.1.3 InChI Key
    WVLHGCRWEHCIOT-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CN(CCN1)C2=C3C(=CC=C2)OCCO3
    2.2 Other Identifiers
    2.2.1 UNII
    510M006KO6
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine

    2. Du 28853

    3. Du-28853

    4. Eltoprazine Hydrochloride

    5. Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-, Hydrochloride

    2.3.2 Depositor-Supplied Synonyms

    1. 98224-03-4

    2. 98206-09-8

    3. 1-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazine

    4. 1-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazine

    5. Eltoprazine [inn]

    6. 1-(1,4-benzodioxan-5-yl)piperazine

    7. 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine

    8. Chembl282614

    9. 510m006ko6

    10. 1-(2,3-dihydrobenzo[1,4]dioxin-5-yl)piperazine

    11. Eltoprazinum [latin]

    12. Eltoprazina [spanish]

    13. Ncgc00159533-01

    14. Eltoprazina

    15. Eltoprazinum

    16. Eltoprazine [mi]

    17. Eltoprazine [mart.]

    18. Schembl177715

    19. Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-

    20. Zinc1347

    21. N-(benzodioxan-5-yl)piperazine

    22. Dtxsid5048425

    23. Unii-510m006ko6

    24. Bcp19313

    25. 1-(1,4-benzodioxan-5-yl)piperazin

    26. Am1234

    27. Bdbm50035057

    28. Mfcd00868056

    29. Pdsp1_000561

    30. Pdsp2_000559

    31. Akos016007669

    32. 1-(1,4-benzodioxan-5-yl)-piperazine

    33. Cs-3216

    34. Db12883

    35. Sb16767

    36. Hy-16687

    37. Ft-0667839

    38. (2,3-dihydro[1,4]benzodioxin-5-yl)piperazine

    39. H11026

    40. 4-(2,3-dihydrobenzo[1,4]dioxin-5-yl)piperazine

    41. A902315

    42. L000982

    43. 1-(2,3-dihydrobenzo[1,4]dioxin-5-yl)-piperazine

    44. 4-(2,3-dihydrobenzo[1,4]dioxin-5-yl)-piperazine

    45. Q5367896

    46. 4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazine

    47. Brd-k86171477-003-01-9

    48. (eltoprazine)1-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazine

    49. 1-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazine Hydrochloride Hydrochloride

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 220.27 g/mol
    Molecular Formula C12H16N2O2
    XLogP31.1
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count1
    Exact Mass220.121177757 g/mol
    Monoisotopic Mass220.121177757 g/mol
    Topological Polar Surface Area33.7 Ų
    Heavy Atom Count16
    Formal Charge0
    Complexity231
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Serotonin Receptor Agonists

    Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)

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