Please Wait
Applying Filters...
menu
    • menu
    Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

    Virtual Booth

    Contact Supplier

    Kikkoman Biochemifa Company advances global health and safety through precision-driven innovation in biotech and food testing.

    Virtual Booth

    Contact Supplier

    Rusan Pharma: Over 30 years of specializing in the treatment of Addiction and Pain Management.

    Virtual Booth

    Contact Supplier

    TransoPharm USA works in the Sourcing and Management of Active Pharmaceutical Ingredients.

    Virtual Booth

    Contact Supplier

    Moehs Group, a reference company in the production of pharmaceutical active ingredients.

    Virtual Booth

    Contact Supplier

    pharmacompass-2-m-2025-10-20

    Virtual Booth

    An Enquiry

    Menu

    Delgocitinib

    ACTIVE PHARMA INGREDIENTS

    DEVELOPMENTS

    INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    DIGITAL CONTENT

    MARKET PLACE

    PATENTS & EXCLUSIVITIES

    PharmaCompass
    $ API Ref.Price (USD/KG) : 348,275Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 1263774-59-9, Jte-052, Jte-052a, Corectim, Leo 124249a, Leo 124249
    Molecular Formula
    C16H18N6O
    Molecular Weight
    310.35  g/mol
    InChI Key
    LOWWYYZBZNSPDT-ZBEGNZNMSA-N
    FDA UNII
    9L0Q8KK220
    Delgocitinib is under investigation in clinical trial NCT03683719 (Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 Mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand Eczema).
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    3-[(3S,4R)-3-methyl-7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile
    2.1.2 InChI
    InChI=1S/C16H18N6O/c1-11-8-22(13(23)2-5-17)16(11)4-7-21(9-16)15-12-3-6-18-14(12)19-10-20-15/h3,6,10-11H,2,4,7-9H2,1H3,(H,18,19,20)/t11-,16-/m0/s1
    2.1.3 InChI Key
    LOWWYYZBZNSPDT-ZBEGNZNMSA-N
    2.1.4 Canonical SMILES
    CC1CN(C12CCN(C2)C3=NC=NC4=C3C=CN4)C(=O)CC#N
    2.1.5 Isomeric SMILES
    C[C@H]1CN([C@]12CCN(C2)C3=NC=NC4=C3C=CN4)C(=O)CC#N
    2.2 Other Identifiers
    2.2.1 UNII
    9L0Q8KK220
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 1,6-diazaspiro(3.4)octane-1-propanenitrile, 3-methyl-beta-oxo-6-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-, (3s,4r)-

    2. 3-((3s,4r)-3-methyl-6-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1,6-diazaspiro(3.4)octan-1-yl)-3-oxopropanenitrile

    3. Jte-052

    2.3.2 Depositor-Supplied Synonyms

    1. 1263774-59-9

    2. Jte-052

    3. Jte-052a

    4. Corectim

    5. Leo 124249a

    6. Leo 124249

    7. Leo-124249a

    8. Leo-124249

    9. Delgocitinib [usan]

    10. 9l0q8kk220

    11. 3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile

    12. 3-((3s,4r)-3-methyl-6-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1,6-diazaspiro(3.4)octan-1-yl)-3-oxopropanenitrile

    13. 3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrile

    14. Delgocitinibum

    15. Corectim (tn)

    16. 3-((3s,4r)-3-methyl-6-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl)-3-oxopropanenitrile

    17. 3-[(3s,4r)-3-methyl-6-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile

    18. Ent-60

    19. Delgocitinib (jan/usan)

    20. Delgocitinib [inn]

    21. Delgocitinib [jan]

    22. Delgocitinib [who-dd]

    23. Unii-9l0q8kk220

    24. Gtpl9619

    25. Jte052

    26. Chembl4297507

    27. Schembl12547007

    28. Chebi:167600

    29. Dtxsid401336933

    30. Ex-a5577

    31. Bdbm50545650

    32. At24880

    33. Leo-124249;jte-052

    34. Bd178539

    35. Hy-109053

    36. Cs-0031558

    37. D11046

    38. A936874

    39. 1,6-diazaspiro(3.4)octane-1-propanenitrile, 3-methyl-.beta.-oxo-6-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-, (3s,4r)-

    40. 1,6-diazaspiro(3.4)octane-1-propanenitrile, 3-methyl-beta-oxo-6-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-, (3s,4r)-

    41. Fhx

    2.4 Create Date
    2011-03-14
    3 Chemical and Physical Properties
    Molecular Weight 310.35 g/mol
    Molecular Formula C16H18N6O
    XLogP31.1
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count2
    Exact Mass310.15420922 g/mol
    Monoisotopic Mass310.15420922 g/mol
    Topological Polar Surface Area88.9 Ų
    Heavy Atom Count23
    Formal Charge0
    Complexity544
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Indication

    Treatment of dermatitis and eczema