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Roche Diagnostics GmbH
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Germany
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Sandhofer Strasse 116 P.O. Box 310120 Mannheim, 68305
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+49 621 759 0
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RG6107 (crovalimab) is an investigational, novel anti-C5 recycling monoclonal antibody designed to block the complement system which plays a vital part of the innate immune system that acts as the body’s first line of defence against infection.


Lead Product(s): Crovalimab

Therapeutic Area: Rare Diseases and Disorders Product Name: RG6107

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 07, 2023

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PATHWAY anti-HER2 test is only FDA approved companion diagnostic indicated as an aid in assessment of HER2 low status in metastatic breast cancer patients, who may consider ENHERTU (fam-trastuzumab deruxtecan-nxki) as a treatment option based on results of Phase 3 trial.


Lead Product(s): Deruxtecan

Therapeutic Area: Oncology Product Name: Enhertu

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: AstraZeneca

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 04, 2022

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The VENTANA PD-L1 (SP263) Assay as a companion diagnostic helps determine which patients with non-small cell lung cancer may be eligible for treatment with Libtayo monotherapy based on the results of the Phase III EMPOWER-Lung 1 study.


Lead Product(s): Cemiplimab

Therapeutic Area: Oncology Product Name: Libtayo

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Regeneron Pharmaceuticals

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 09, 2022

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The VENTANA MMR RxDx Panel is the first immunohistochemistry (IHC) companion diagnostic test to aid in identifying patients whose solid tumours are deficient in DNA mismatch repair (dMMR), and who may be eligible for KEYTRUDA® (pembrolizumab).


Lead Product(s): Pembrolizumab,Lenvatinib

Therapeutic Area: Oncology Product Name: Keytruda

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Merck & Co

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 11, 2022

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Inotrem entered a worldwide licensing agreement with Roche Diagnostics for the commercialization of a mechanism-based companion diagnostic test using a soluble plasma protein.


Lead Product(s): Nangibotide

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Peptide

Recipient: Inotrem

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement January 21, 2020

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