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18 Nov 2025
// BUSINESSWIRE
https://www.businesswire.com/news/home/20251112165105/en/Colgate-Palmolive-Webcasts-Fireside-Chat-at-the-Morgan-Stanley-Global-Consumer-Retail-Conference

19 Nov 2024
// FDA
https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/colgate-palmolivetoms-maine-inc-687043-11052024

23 Aug 2023
// FDA
https://www.pharmacompass.com/pdf/news/enforcement-report-week-of-august-23-2023-6184.pdf

06 Jan 2020
// BIOS PECTRUM ASIA
https://www.biospectrumasia.com/news/30/15187/colgate-to-revolutionize-oral-health-through-novel-technology.html

22 Mar 2017
// FDA
https://www.pharmacompass.com/pdf/news/enforcement-report-week-of-march-22-2017-1490161550.pdf
https://www.pharmacompass.com/pdf/news/colgate-palmolives-generic-periogard-approve-in-us-as-anti-microbial-oral-rinse-1454496978.pdf
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Details:
Cetylpyridinium Chloride is a small molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Gingivitis.
Lead Product(s): Cetylpyridinium Chloride,Zinc Lactate,Sodium Fluoride
Therapeutic Area: Dental and Oral Health Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable December 04, 2025

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Lead Product(s) : Cetylpyridinium Chloride,Zinc Lactate,Sodium Fluoride
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Cetylpyridinium Chloride is a small molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Gingivitis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 04, 2025

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Details:
L-Arginine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Hypersensitivity.
Lead Product(s): L-Arginine
Therapeutic Area: Immunology Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Vitamins/Minerals/Inorganic Salts
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable December 02, 2025

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Lead Product(s) : L-Arginine
Therapeutic Area : Immunology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : L-Arginine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Hypersensitivity.
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
December 02, 2025

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Details:
Stannous Fluoride is a small molecule drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Dental Calculus.
Lead Product(s): Tin Fluoride
Therapeutic Area: Dental and Oral Health Brand Name: Undisclosed
Study Phase: Phase II/ Phase IIIProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable October 31, 2025

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Lead Product(s) : Tin Fluoride
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase II/ Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Efficacy of Stannous Fluoride Toothpaste vs Regular Fluoride Toothpaste
Details : Stannous Fluoride is a small molecule drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Dental Calculus.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 31, 2025

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Details:
Stannous Fluoride is a small molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Halitosis.
Lead Product(s): Tin Fluoride
Therapeutic Area: Dental and Oral Health Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable October 31, 2025

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Lead Product(s) : Tin Fluoride
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Clinical Study on Efficacy of New Toothpaste in Bangkok Participants
Details : Stannous Fluoride is a small molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Halitosis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 31, 2025

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Details:
Sodium Monofluorophosphate is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Dental Plaque.
Lead Product(s): Fluorophosphate
Therapeutic Area: Dental and Oral Health Brand Name: Undisclosed
Study Phase: Phase IVProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable June 19, 2025

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Lead Product(s) : Fluorophosphate
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase IV
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Comparative Efficacy of Floss vs Essential Oil/CPC+Zn in Reducing Plaque & Gingivitis
Details : Sodium Monofluorophosphate is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Dental Plaque.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 19, 2025

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Details:
Stannous Fluoride is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Gingivitis.
Lead Product(s): Tin Fluoride
Therapeutic Area: Dental and Oral Health Brand Name: Undisclosed
Study Phase: Phase IVProduct Type: Miscellaneous
Sponsor: University of Texas Health Science Center at Houston
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable May 12, 2025

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Lead Product(s) : Tin Fluoride
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase IV
Partner/Sponsor/Collaborator : University of Texas Health Science Center at Houston
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Stannous Fluoride is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Gingivitis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 12, 2025

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Details:
CSPR is a drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dentin Sensitivity.
Lead Product(s): CSPR
Therapeutic Area: Dental and Oral Health Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Undisclosed
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable May 07, 2025

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Lead Product(s) : CSPR
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Dentinal Hypersensitivity Reduction Efficacy Study
Details : CSPR is a drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dentin Sensitivity.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 07, 2025

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Details:
Hydrogen Peroxide is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of undefined medical condition.
Lead Product(s): Hydrogen Peroxide,Fluoride
Therapeutic Area: Undisclosed Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable May 04, 2025

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Lead Product(s) : Hydrogen Peroxide,Fluoride
Therapeutic Area : Undisclosed
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Clinical Study to Evaluate the Tooth Whitening Efficacy
Details : Hydrogen Peroxide is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 04, 2025

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Details:
Nanohydroxyapatite is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dentin Sensitivity.
Lead Product(s): Nanohydroxyapatite
Therapeutic Area: Dental and Oral Health Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable May 04, 2025

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Lead Product(s) : Nanohydroxyapatite
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Nanohydroxyapatite is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dentin Sensitivity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 04, 2025

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Details:
Sensitivity Relief Toothpaste is a drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dental Plaque.
Lead Product(s): Sensitivity Relief Toothpaste
Therapeutic Area: Dental and Oral Health Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Undisclosed
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable May 02, 2025

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Lead Product(s) : Sensitivity Relief Toothpaste
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Arginine Plaque Metabolism Pilot Clinical Study
Details : Sensitivity Relief Toothpaste is a drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dental Plaque.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 02, 2025

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RLD : No
TE Code :
Dosage Form : SOLUTION; DENTAL
Proprietary Name : PERIOGARD
Dosage Strength : 0.12%
Approval Date : 1994-01-14
Application Number : 73695
RX/OTC/DISCN : DISCN
RLD : No
TE Code :

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RLD : No
TE Code : AT
Dosage Form : SOLUTION; DENTAL
Proprietary Name : PERIOGARD
Dosage Strength : 0.12%
Approval Date : 2016-01-28
Application Number : 203212
RX/OTC/DISCN : RX
RLD : No
TE Code : AT

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RLD : No
TE Code :
Dosage Form : PASTE; TOPICAL
Proprietary Name : ORABASE HCA
Dosage Strength : 0.5%
Approval Date : 1982-01-01
Application Number : 83205
RX/OTC/DISCN : DISCN
RLD : No
TE Code :

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RLD : Yes
TE Code :
Dosage Form : PASTE; DENTAL
Proprietary Name : COLGATE TOTAL
Dosage Strength : 0.24%;0.3%
Approval Date : 1997-07-11
Application Number : 20231
RX/OTC/DISCN : DISCN
RLD : Yes
TE Code :

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