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Details:
BND-22 (SAR444881), is a humanized IgG4, antagonist antibody targeting the ILT2 receptor in development for the treatment of solid tumors, is an inhibitory receptor expressed on both innate and adaptive immune cells that binds MHC class I molecules.
Lead Product(s): BND-22,Pembrolizumab
Therapeutic Area: Oncology Product Name: SAR444881
Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable May 23, 2022
Details:
BND-22 (SAR444881), a novel immune checkpoint inhibitor targeting the Immunoglobulin-like transcript receptor 2 or ILT2, enhances anti-tumor activity of T cells and NK cells.
Lead Product(s): BND-22,Pembrolizumab,Cetuximab
Therapeutic Area: Oncology Product Name: BND-22
Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Sanofi
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 20, 2022
Details:
The financing has sopported the development of BND-22 (SAR444881), the company’s Ig-Like Transcript 2 (ILT2) receptor-blocking antibody, and the first patient has been dosed in the first-in-human, phase 1 clinical trial of BND22.
Lead Product(s): BND-22,Pembrolizumab
Therapeutic Area: Oncology Product Name: SAR444881
Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Deep Insight
Deal Size: $15.0 million Upfront Cash: Undisclosed
Deal Type: Series C Financing November 03, 2021
Details:
BND-22 is a humanized IgG4, antagonist antibody targeting the Ig-like transcript 2 (ILT2) receptor in development for the treatment of solid tumors.
Lead Product(s): BND-22
Therapeutic Area: Oncology Product Name: BND-22
Highest Development Status: IND EnablingProduct Type: Large molecule
Partner/Sponsor/Collaborator: Sanofi
Deal Size: $1,125.0 million Upfront Cash: $125.0 million
Deal Type: Licensing Agreement January 12, 2021