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Biond Biologics
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BND-22 (SAR444881), is a humanized IgG4, antagonist antibody targeting the ILT2 receptor in development for the treatment of solid tumors, is an inhibitory receptor expressed on both innate and adaptive immune cells that binds MHC class I molecules.


Lead Product(s): BND-22,Pembrolizumab

Therapeutic Area: Oncology Product Name: SAR444881

Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 23, 2022

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BND-22 (SAR444881), a novel immune checkpoint inhibitor targeting the Immunoglobulin-like transcript receptor 2 or ILT2, enhances anti-tumor activity of T cells and NK cells.


Lead Product(s): BND-22,Pembrolizumab,Cetuximab

Therapeutic Area: Oncology Product Name: BND-22

Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Sanofi

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 20, 2022

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The financing has sopported the development of BND-22 (SAR444881), the company’s Ig-Like Transcript 2 (ILT2) receptor-blocking antibody, and the first patient has been dosed in the first-in-human, phase 1 clinical trial of BND22.


Lead Product(s): BND-22,Pembrolizumab

Therapeutic Area: Oncology Product Name: SAR444881

Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Deep Insight

Deal Size: $15.0 million Upfront Cash: Undisclosed

Deal Type: Series C Financing November 03, 2021

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BND-22 is a humanized IgG4, antagonist antibody targeting the Ig-like transcript 2 (ILT2) receptor in development for the treatment of solid tumors.


Lead Product(s): BND-22

Therapeutic Area: Oncology Product Name: BND-22

Highest Development Status: IND EnablingProduct Type: Large molecule

Partner/Sponsor/Collaborator: Sanofi

Deal Size: $1,125.0 million Upfront Cash: $125.0 million

Deal Type: Licensing Agreement January 12, 2021

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