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Details:

The net proceeds from the offering for continued development of its VK2809, a small molecule selective thyroid hormone receptor beta agonist. It is currently being evaluated in a Phase 2b study for for the treatment of non-alcoholic steatohepatitis and fibrosis.


Lead Product(s): VK2809

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: VK2809

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Morgan Stanley

Deal Size: $632.5 million Upfront Cash: Undisclosed

Deal Type: Public Offering March 04, 2024

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Details:

The net proceeds from the offering for continued development of its VK2809, a small molecule selective thyroid hormone receptor beta agonist. It is currently being evaluated in a Phase 2b study for for the treatment of non-alcoholic steatohepatitis and fibrosis.


Lead Product(s): VK2809

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: VK2809

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Morgan Stanley

Deal Size: $550.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering February 28, 2024

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The net proceeds from the proposed offering for continued development of its VK2809, small molecule selective thyroid hormone receptor beta agonist. It is being evaluated in clinical studies for the treatment of non-alcoholic steatohepatitis and fibrosis.


Lead Product(s): VK2809

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: VK2809

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Morgan Stanley

Deal Size: $350.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering February 27, 2024

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VK2809 novel liver-selective thyroid hormone receptor beta agonist,which is being evaluated for the treatment of patients with biopsy-confirmed non-alcoholic steatohepatitis.


Lead Product(s): VK2809

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: VK2809

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 13, 2023

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VK2809 is an orally available, selective agonist of the thyroid beta receptor, suggesting promising therapeutic potential in a range of lipid disorders. Drug is currently being evaluated for biopsy-confirmed non-alcoholic steatohepatitis.


Lead Product(s): VK2809

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: VK2809

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 16, 2023

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Details:

VK2809 is an orally available, selective agonist of the thyroid beta receptor, suggesting promising therapeutic potential in a range of lipid disorders. Drug is currently being evaluated in a Phase 2b clinical trial for biopsy-confirmed non-alcoholic steatohepatitis.


Lead Product(s): VK2809

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: VK2809

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 09, 2023

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Details:

Data from the company's 12-week Phase 2 study of VK2809 in patients with non-alcoholic fatty liver disease (NAFLD) and elevated low-density lipoprotein cholesterol (LDL-C) will be presented at the Digital International Liver Congress™ 2020.


Lead Product(s): VK2809

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: VK2089

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 20, 2020

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