Synopsis
Synopsis
0
API Suppliers
0
USDMF
0
CEP/COS
0
JDMF
0
EU WC
0
KDMF
0
NDC API
0
VMF
0
Listed Suppliers
0
EDQM
0
USP
0
JP
0
Others
0
FDF Dossiers
0
FDA Orange Book
0
Europe
0
Canada
0
Australia
0
South Africa
0
Listed Dossiers
DRUG PRODUCT COMPOSITIONS
0
US Patents
0
US Exclusivities
0
Health Canada Patents
US Medicaid
NA
Annual Reports
NA
Regulatory FDF Prices
NA
0
API
0
FDF
0
Data Compilation #PharmaFlow
0
Stock Recap #PipelineProspector
0
Weekly News Recap #Phispers
0
News #PharmaBuzz
1. Desoxyepothilone B
2. 12,13-desoxyepothilone B
3. Depob Cpd
4. Epothilon D
5. Epothiolone D
6. Epothilone B, Desoxy
7. Kos 862
8. Kos-862
9. Kos862
1. 189453-10-9
2. Desoxyepothilone B
3. (-)-desoxyepothilone B
4. Kos-862
5. 12,13-desoxyepothilone B
6. (-)-epothilone D
7. Epothilon D
8. Nsc-703147
9. Kos 862
10. 12,13-deoxyepothilone B
11. Epothiolone D
12. Depob Cpd
13. Oxacyclohexadec-13-ene-2,6-dione, 4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1e)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-, (4s,7r,8s,9s,13z,16s)-
14. Nsc 703147
15. T0358e0yuf
16. Epothilone B, Desoxy
17. 12,13-desoxyepothilone B, Cis
18. Kos862
19. R1492
20. Chebi:29579
21. Dtxsid70880053
22. Nsc703147
23. (4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(e)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione
24. Oxacyclohexadec-13-ene-2,6-dione, 4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-((1e)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl)-, (4s,7r,8s,9s,13z,16s)-
25. (4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-((e)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl)-1-oxacyclohexadec-13-ene-2,6-dione
26. Refchem:137339
27. Dtxcid901022595
28. (4s-(4r*,7s,8r*,9r*,13z,16r*(e)))-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-(1-methyl-2-(2-methyl-4-thiazolyl)ethenyl)oxacyclohexadec-13-ene-2,6-dione
29. R-1492
30. Mfcd27976357
31. (4s,7r,8s,9s,16s,z)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-((e)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)oxacyclohexadec-13-ene-2,6-dione
32. Epothilone D (synthetic)
33. (4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(e)-1-methyl-2-(2-methylthiazol-4-yl)vinyl]-1-oxacyclohexadec-13-ene-2,6-dione
34. Epd
35. Unii-t0358e0yuf
36. Utidelone
37. Epothilone-d
38. Depob
39. Utidelone [inn]
40. Epo D
41. Epothilone D [mi]
42. Schembl4415
43. 12,13-desoxy-epothilone B
44. Chembl96172
45. Z-12,13-desoxyepothilone B
46. Epothilone D [who-dd]
47. C27h41no5s
48. Orb1679023
49. Ex-a495
50. Glxc-06445
51. Biologically Synthesized Epothilone D
52. Lmpk04000001
53. Nsc721085
54. Akos025401598
55. Cs-0655
56. Db01873
57. Fe22752
58. Nsc-721085
59. Ac-22616
60. Hy-15278
61. Brd-k52762805-001-01-2
62. (4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-(1e)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl-oxacyclohexadec-13-ene-2,6-dione
63. (4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1e)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione
64. (4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1e)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]oxacyclohexadec-13-ene-2,6-dione
65. (4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1e)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]oxacyclohexadec-13-ene- 2,6-dione
66. (4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1e)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]oxacyclohexadec-13-ene-2,6-dione; (-)-desoxyepothilone B; (-)-epothilone D; 12,13-deoxyepo
67. (4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(e)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]oxacyclohexadec-13-ene-2,6-dione
68. (4s-(4r*,8r*,9r*,13z,16r*(e)))-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-(1-methyl-2-(2-methyl-4-thiazolyl)ethenyl)oxacyclohexadec-13-ene-2,6-dione
69. Oxacyclohexadec-13-ene-2,6-dione, 4,6-dihydroxy-5,5,7,9,13-pentamethyl-16-((1e)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl)-, (4s,7r,8s,9s,13z,16s)-
70. Oxacyclohexadec-13-ene-2,6-dione, 4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-(1-methyl-2-(2-methyl-4-thiazolyl)ethenyl)-, (4s-(4r*,7s,8r*,9r*,13z,16r*(e)))-
| Molecular Weight | 491.7 g/mol |
|---|---|
| Molecular Formula | C27H41NO5S |
| XLogP3 | 5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 2 |
| Exact Mass | Da |
| Monoisotopic Mass | Da |
| Topological Polar Surface Area | 125 |
| Heavy Atom Count | 34 |
| Formal Charge | 0 |
| Complexity | 777 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 5 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 2 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in colorectal cancer, lung cancer, breast cancer, solid tumors, and prostate cancer.
Tubulin Modulators
Agents that interact with TUBULIN to inhibit or promote polymerization of MICROTUBULES.
L - Antineoplastic and immunomodulating agents
L01 - Antineoplastic agents
L01D - Cytotoxic antibiotics and related substances
L01DC - Other cytotoxic antibiotics
L01DC05 - Utidelone
ATCvet Code
QL - Antineoplastic and immunomodulating agents
QL01 - Antineoplastic agents
QL01D - Cytotoxic antibiotics and related substances
QL01DC - Other cytotoxic antibiotics
QL01DC05 - Utidelone
The principal mechanism of the epothilone class is inhibition of microtubule function. Microtubules are essential to cell division, and epothilones therefore stop cells from properly dividing.
ABOUT THIS PAGE
27
PharmaCompass offers a list of Utidelone API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Utidelone manufacturer or Utidelone supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Utidelone manufacturer or Utidelone supplier.
A Utidelone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Utidelone, including repackagers and relabelers. The FDA regulates Utidelone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Utidelone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Utidelone supplier is an individual or a company that provides Utidelone active pharmaceutical ingredient (API) or Utidelone finished formulations upon request. The Utidelone suppliers may include Utidelone API manufacturers, exporters, distributors and traders.
Utidelone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Utidelone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Utidelone GMP manufacturer or Utidelone GMP API supplier for your needs.
A Utidelone CoA (Certificate of Analysis) is a formal document that attests to Utidelone's compliance with Utidelone specifications and serves as a tool for batch-level quality control.
Utidelone CoA mostly includes findings from lab analyses of a specific batch. For each Utidelone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Utidelone may be tested according to a variety of international standards, such as European Pharmacopoeia (Utidelone EP), Utidelone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Utidelone USP).
