UNII-WEC6I2K1FC

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

57 API Suppliers, 12 USDMF, 10 JDMF, 10 EU WC, 14 KDMF, 6 NDC API, 38 Listed Suppliers

DEVELOPMENTS

3 Drug(s) in Development

3 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Exports, API Imports

INTERMEDIATES

30 Suppliers

30 Suppliers

DOSSIERs // Finished Dosage Formulations

33 Dossiers, 6 FDA Orange Book, 20 Europe, 4 Canada, 3 Listed Dossiers

DRUG PRODUCT COMPOSITION

TABLET;ORAL - EQ 40MG MEDOXOMIL, TABLET;ORAL - EQ 80MG MEDOXOMIL, TABLET;ORAL - EQ 40MG MEDOXOMIL;12.5MG, TABLET;ORAL - EQ 40MG MEDOXOMIL;25MG

TABLET;ORAL - EQ 40MG MEDOXOMIL
TABLET;ORAL - EQ 80MG MEDOXOMIL
TABLET;ORAL - EQ 40MG MEDOXOMIL;12.5MG
TABLET;ORAL - EQ 40MG MEDOXOMIL;25MG

RELATED EXCIPIENT COMPANIES

Suppliers, 17 Kerry, 13 Roquette, 13 SPI Pharma, 10 Sigachi Industries, 10 Microlex e.U, 10 Corel Pharma Chem, 8 Gangwal Healthcare, 7 Seppic, 6 Lonza Capsugel, 5 Ideal Cures Pvt Ltd, 5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 5 Gangwal Chemicals, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 3 DFE Pharma, 3 Kima Chemical, 3 Vasa Pharmachem, 3 Prachin Chemical, 2 The Dow Chemical Company, 2 DKSH, 2 Ingredion Pharma Solutions, 1 BASF, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Pharmatrans-Sanaq, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Jai Radhe Sales, 1 Pfanstiehl, 1 Qualicaps, 1 Aeon Procare, 1 ACG Worldwide, 1 Rochem International Inc

EXCIPIENTS BY APPLICATIONS

42 Coating Systems & Additives, 42 Fillers, Diluents & Binders, 22 Direct Compression, 21 Controlled & Modified Release, 17 Disintegrants & Superdisintegrants, 12 Lubricants & Glidants, 12 Chewable & Orodispersible Aids, 12 Taste Masking, 12 Granulation, 11 Thickeners and Stabilizers, 10 Co-Processed Excipients, 7 Film Formers & Plasticizers, 5 Empty Capsules, 4 Vegetarian Capsules, 4 API Stability Enhancers, 3 Parenteral, 3 Rheology Modifiers, 2 Coloring Agents, 2 Emulsifying Agents, 1 Solubilizers

GLOBAL SALES INFORMATION

14 US Medicaid Prescriptions, 14 Finished Drug Prices

MARKET PLACE

14 APIs

14 APIs

PATENTS

16 US Patents, 2 Health Canada Patents

ANALYTICAL SOLUTION(s)

5 Other Ref. Standards

5 Other Ref. Standards

DIGITAL CONTENT

1 Data Compilations & Company Tracker #PharmaFlow, 12 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

1,671

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

259.00

Annual Reports

647.00

FDF Market Place

EXCIPIENTS

142

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 863031-24-7, Azilsartan (medoxomil monopotassium), Azilsartan kamedoxomil, Azilsartan medoxomil monopotassium, Bcp11249, Sb19561

Molecular Formula

C₃₀H₂₃KN₄O₈

Molecular Weight

606.6 g/mol

InChI Key

IHWFKDWIUSZLCJ-UHFFFAOYSA-M

1 2D Structure

UNII-WEC6I2K1FC

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

potassium;(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-1-oxa-4-aza-2-azanidacyclopent-3-en-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate

2.1.2 InChI

InChI=1S/C30H24N4O8.K/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26;/h4-14H,3,15-16H2,1-2H3,(H,32,33,36);/q;+1/p-1

2.1.3 InChI Key

IHWFKDWIUSZLCJ-UHFFFAOYSA-M

2.1.4 Canonical SMILES

CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)O[N-]5)C(=O)OCC6=C(OC(=O)O6)C.[K+]

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. 863031-24-7

2. Azilsartan (medoxomil Monopotassium)

3. Azilsartan Kamedoxomil

4. Azilsartan Medoxomil Monopotassium

5. Bcp11249

6. Sb19561

7. Hy-17458

8. Potassium;(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-1-oxa-4-aza-2-azanidacyclopent-3-en-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate

9. Potassium 3-(4'-((2-ethoxy-7-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)-1h-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-yl)-5-oxo-5h-1,2,4-oxadiazol-2-ide

2.3 Create Date

2015-09-21

3 Chemical and Physical Properties

Molecular Formula	C₃₀H₂₃KN₄O₈
Molecular Weight	606.6 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	10
Exact Mass	606.11529519 g/mol
Monoisotopic Mass	606.11529519 g/mol
Topological Polar Surface Area	129 Å²
Heavy Atom Count	43
Formal Charge	0
Complexity	1110
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 FDA Pharmacological Classification

4.1.1 Pharmacological Classes

Angiotensin 2 Type 1 Receptor Antagonists [MoA]; Decreased Blood Pressure [PE]; Angiotensin 2 Receptor Blocker [EPC]

Find Azilsartan manufacturers, exporters & distributors on PharmaCompass

UNII-WEC6I2K1FC

UNII-WEC6I2K1FC

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

57 API Suppliers

12 USDMF

10 JDMF

10 EU WC

14 KDMF

6 NDC API

38 Listed Suppliers

DEVELOPMENTS

3 Drug(s) in Development

PRICE INFORMATION

API Reference Price

API Exports

API Imports

INTERMEDIATES

30 Suppliers

DOSSIERs // Finished Dosage Formulations

33 Dossiers

6 FDA Orange Book

20 Europe

4 Canada

3 Listed Dossiers

DRUG PRODUCT COMPOSITION

TABLET;ORAL - EQ 40MG MEDOXOMIL

TABLET;ORAL - EQ 80MG MEDOXOMIL

TABLET;ORAL - EQ 40MG MEDOXOMIL;12.5MG

TABLET;ORAL - EQ 40MG MEDOXOMIL;25MG

RELATED EXCIPIENT COMPANIES

Suppliers

17 Kerry

13 Roquette

13 SPI Pharma

10 Sigachi Industries

10 Microlex e.U

10 Corel Pharma Chem

8 Gangwal Healthcare

7 Seppic

6 Lonza Capsugel

5 Ideal Cures Pvt Ltd

5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

5 Gangwal Chemicals

5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

3 DFE Pharma

3 Kima Chemical

3 Vasa Pharmachem

3 Prachin Chemical

2 The Dow Chemical Company

2 DKSH

2 Ingredion Pharma Solutions

1 BASF

1 Qianhao Chemical (Hebei) Co., Ltd

1 Pharmatrans-Sanaq

1 Shijiazhuang Huaxu Pharmaceutical

1 Jai Radhe Sales

1 Pfanstiehl

1 Qualicaps

1 Aeon Procare

1 ACG Worldwide

1 Rochem International Inc

EXCIPIENTS BY APPLICATIONS

42 Coating Systems & Additives

42 Fillers, Diluents & Binders

22 Direct Compression

21 Controlled & Modified Release

17 Disintegrants & Superdisintegrants

12 Lubricants & Glidants

12 Chewable & Orodispersible Aids

12 Taste Masking

12 Granulation

11 Thickeners and Stabilizers

10 Co-Processed Excipients

7 Film Formers & Plasticizers

5 Empty Capsules

4 Vegetarian Capsules

4 API Stability Enhancers