Find Tubulysin A manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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JDMF

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NDC API

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Chemistry

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Also known as: 205304-86-5, X9rp3ade9z, (2s,4r)-4-[[2-[(1r,3r)-1-acetyloxy-4-methyl-3-[3-methylbutanoyloxymethyl-[(2s,3s)-3-methyl-2-[[(2r)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoic acid, Dtxsid90478254, Tuba compound, (2s,4r)-4-((2-((1r,3r)-1-acetyloxy-4-methyl-3-(3-methylbutanoyloxymethyl-((2s,3s)-3-methyl-2-(((2r)-1-methylpiperidine-2-carbonyl)amino)pentanoyl)amino)pentyl)-1,3-thiazole-4-carbonyl)amino)-5-(4-hydroxyphenyl)-2-methylpentanoic acid
Molecular Formula
C43H65N5O10S
Molecular Weight
844.1  g/mol
InChI Key
IBEDDHUHZBDXGB-OEJISELMSA-N
FDA UNII
X9RP3ADE9Z

Tubulysin A
has both antiangiogenic and antineoplastic activities; structure in first source
1 2D Structure

Tubulysin A

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,4R)-4-[[2-[(1R,3R)-1-acetyloxy-4-methyl-3-[3-methylbutanoyloxymethyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoic acid
2.1.2 InChI
InChI=1S/C43H65N5O10S/c1-10-27(6)38(46-40(53)34-13-11-12-18-47(34)9)42(54)48(24-57-37(51)19-25(2)3)35(26(4)5)22-36(58-29(8)49)41-45-33(23-59-41)39(52)44-31(20-28(7)43(55)56)21-30-14-16-32(50)17-15-30/h14-17,23,25-28,31,34-36,38,50H,10-13,18-22,24H2,1-9H3,(H,44,52)(H,46,53)(H,55,56)/t27-,28-,31+,34+,35+,36+,38-/m0/s1
2.1.3 InChI Key
IBEDDHUHZBDXGB-OEJISELMSA-N
2.2 Other Identifiers
2.2.1 UNII
X9RP3ADE9Z
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Tuba Compound

2.3.2 Depositor-Supplied Synonyms

1. 205304-86-5

2. X9rp3ade9z

3. (2s,4r)-4-[[2-[(1r,3r)-1-acetyloxy-4-methyl-3-[3-methylbutanoyloxymethyl-[(2s,3s)-3-methyl-2-[[(2r)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoic Acid

4. Dtxsid90478254

5. Tuba Compound

6. (2s,4r)-4-((2-((1r,3r)-1-acetyloxy-4-methyl-3-(3-methylbutanoyloxymethyl-((2s,3s)-3-methyl-2-(((2r)-1-methylpiperidine-2-carbonyl)amino)pentanoyl)amino)pentyl)-1,3-thiazole-4-carbonyl)amino)-5-(4-hydroxyphenyl)-2-methylpentanoic Acid

7. Refchem:900708

8. Dtxcid90429064

9. 633-790-6

10. Tubulysin A,tuba

11. Tuba

12. Chebi:80034

13. Tubulysin A?

14. Tubulysin-a

15. Unii-x9rp3ade9z

16. Chembl256922

17. Orb1679051

18. Schembl12219629

19. Ex-a5466b

20. Mfcd12912448

21. Ncgc00485650-01

22. Ac-37918

23. Bp-41463

24. Da-58800

25. Hy-15995

26. G13808

27. Q27149181

28. Tubulysin A, >=95% (hplc), From Streptomyces Sp., Film

29. (2s,4r)-4-(2-((1r,3r)-1-acetoxy-4-methyl-3-((2s,3s)-3-methyl-n-(((3-methylbutanoyl)oxy)methyl)-2-((r)-1-methylpiperidine-2-carboxamido)pentanamido)pentyl)thiazole-4-carboxamido)-5-(4-hydroxyphenyl)-2-methylpentanoic Acid

30. Benzenepentanoic Acid, .gamma.-(((2-((1r,3r)-1-(acetyloxy)-4-methyl-3-(((2s,3s)-3-methyl-2-((((2r)-1-methyl-2-piperidinyl)carbonyl)amino)-1-oxopentyl)((3-methyl-1-oxobutoxy)methyl)amino)pentyl)-4-thiazolyl)carbonyl)amino)-4-hydroxy-.alpha.-methyl-, (.alpha.s,.gamma.r)-

31. Benzenepentanoic Acid, Gamma-(((2-((1r,3r)-1-(acetyloxy)-4-methyl-3-(((2s,3s)-3-methyl-2-((((2r)-1-methyl-2-piperidinyl)carbonyl)amino)-1-oxopentyl)((3-methyl-1-oxobutoxy)methyl)amino)pentyl)-4-thiazolyl)carbonyl)amino)-4-hydroxy-alpha-methyl-, (.alp

2.4 Create Date
2007-02-07
3 Chemical and Physical Properties
Molecular Weight 844.1 g/mol
Molecular Formula C43H65N5O10S
XLogP34.7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count13
Rotatable Bond Count24
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area233
Heavy Atom Count59
Formal Charge0
Complexity1390
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 205304-86-5 / Tubulysin A API manufacturers, exporters & distributors?

Tubulysin A manufacturers, exporters & distributors 1

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API | Excipient name

Tubulysin A

Synonyms

205304-86-5, X9rp3ade9z, (2s,4r)-4-[[2-[(1r,3r)-1-acetyloxy-4-methyl-3-[3-methylbutanoyloxymethyl-[(2s,3s)-3-methyl-2-[[(2r)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoic acid, Dtxsid90478254, Tuba compound, (2s,4r)-4-((2-((1r,3r)-1-acetyloxy-4-methyl-3-(3-methylbutanoyloxymethyl-((2s,3s)-3-methyl-2-(((2r)-1-methylpiperidine-2-carbonyl)amino)pentanoyl)amino)pentyl)-1,3-thiazole-4-carbonyl)amino)-5-(4-hydroxyphenyl)-2-methylpentanoic acid

Cas Number

205304-86-5

Unique Ingredient Identifier (UNII)

X9RP3ADE9Z

About Tubulysin A

has both antiangiogenic and antineoplastic activities; structure in first source

Tubulysin A Manufacturers

A Tubulysin A manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tubulysin A, including repackagers and relabelers. The FDA regulates Tubulysin A manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tubulysin A API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Tubulysin A manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

Tubulysin A Suppliers

A Tubulysin A supplier is an individual or a company that provides Tubulysin A active pharmaceutical ingredient (API) or Tubulysin A finished formulations upon request. The Tubulysin A suppliers may include Tubulysin A API manufacturers, exporters, distributors and traders.

click here to find a list of Tubulysin A suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

Tubulysin A GMP

Tubulysin A Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tubulysin A GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Tubulysin A GMP manufacturer or Tubulysin A GMP API supplier for your needs.

Tubulysin A CoA

A Tubulysin A CoA (Certificate of Analysis) is a formal document that attests to Tubulysin A's compliance with Tubulysin A specifications and serves as a tool for batch-level quality control.

Tubulysin A CoA mostly includes findings from lab analyses of a specific batch. For each Tubulysin A CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tubulysin A may be tested according to a variety of international standards, such as European Pharmacopoeia (Tubulysin A EP), Tubulysin A JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tubulysin A USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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