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    Chemistry

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    Also known as: 136-47-0, Tetracaine hcl, Butethanol, Amethocaine hydrochloride, Pantocaine, Curtacain
    Molecular Formula
    C15H25ClN2O2
    Molecular Weight
    300.82  g/mol
    InChI Key
    PPWHTZKZQNXVAE-UHFFFAOYSA-N
    FDA UNII
    5NF5D4OPCI
    Tetracaine Hydrochloride
    A potent local anesthetic of the ester type used for surface and spinal anesthesia.
    1 2D Structure

    Tetracaine Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride
    2.1.2 InChI
    InChI=1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
    2.1.3 InChI Key
    PPWHTZKZQNXVAE-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    5NF5D4OPCI
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Amethocaine

    2. Ametop

    3. Dicaine

    4. Hydrochloride, Tetrracaine

    5. Pantocaine

    6. Pontocaine

    7. Tetracaine

    8. Tetracaine Monohydrochloride

    9. Tetrakain

    10. Tetrracaine Hydrochloride

    2.3.2 Depositor-Supplied Synonyms

    1. 136-47-0

    2. Tetracaine Hcl

    3. Butethanol

    4. Amethocaine Hydrochloride

    5. Pantocaine

    6. Curtacain

    7. Menonasal

    8. Anethaine

    9. Dicainum

    10. Tetracaine, Hcl

    11. Tetracaine (hydrochloride)

    12. Butylocaine

    13. 2-(dimethylamino)ethyl 4-(butylamino)benzoate Hydrochloride

    14. Tetocaine

    15. Tetraca

    16. Tetracainehydrochloride

    17. 5nf5d4opci

    18. 2-(dimethylamino)ethyl P-(butylamino)benzoate Monohydrochloride

    19. Nsc-757337

    20. 4-(butylamino)benzoic Acid 2-(dimethylamino)ethyl Ester Hydrochloride

    21. Benzoic Acid, 4-(butylamino)-, 2-(dimethylamino)ethyl Ester, Monohydrochloride

    22. Mls000069780

    23. Tetracaine Hydrochloride (pontocaine)

    24. Anethain

    25. Decicain

    26. Decicaine

    27. Dessicain

    28. Intercaine

    29. Leocaine

    30. Pantocain

    31. Smr000058522

    32. Tonexol

    33. Anacel

    34. Gingicain M

    35. Dsstox_cid_22448

    36. Dsstox_rid_80027

    37. Dsstox_gsid_42448

    38. Tetracainium Chloridum

    39. Tetracaine Chlorhydrate

    40. 2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride

    41. Viractin

    42. Tetracaine Monohydrochloride

    43. Amethocaine Monohydrochloride

    44. Sr-01000075240

    45. Ncgc00016049-02

    46. Cas-136-47-0

    47. Einecs 205-248-5

    48. Unii-5nf5d4opci

    49. Exactacain

    50. Amethocalne Hcl

    51. Tetracaine Hydrochloride [usp:jan]

    52. Mfcd00038912

    53. P-butylaminobenzoyl-2-dimethylaminoethanol Hydrochloride

    54. 2-dimethylaminoethanol 4-n-butylaminobenzoate Hydrochloride

    55. Pontocaine Hydrochloride

    56. 2-(dimethylamino)ethyl P-(butylamino)benzoate Hydrochloride

    57. Tetracaini Hydrochloridum

    58. Opera_id_1220

    59. P-(butylamino)benzoic Acid, 2-(dimethylamino)ethyl Ester, Hydrochloride

    60. Dicainum [who-ip]

    61. Schembl24370

    62. Mls002222164

    63. Protocaine Hydrochloride (tn)

    64. Spectrum1500564

    65. 4-butylaminobenzoic Acid Dimethylaminoethyl Ester Hcl

    66. Chebi:9469

    67. Chembl1255654

    68. Dtxsid6042448

    69. Tetracaine For System Suitability

    70. Tetracaine Hydrochloride, >=99%

    71. Hms1569d04

    72. Hms1921c17

    73. Pharmakon1600-01500564

    74. Act04762

    75. Bcp26339

    76. Hy-b0473

    77. Tox21_110290

    78. Tox21_501211

    79. Ac-774

    80. Ccg-39266

    81. Nsc757337

    82. S2573

    83. Tetracaine Hydrochloride [mi]

    84. Tetracaine Hydrochloride (jp17/usp)

    85. Tetracaine Hydrochloride [jan]

    86. Akos015888160

    87. Tox21_110290_1

    88. Ks-5059

    89. Lp01211

    90. Nsc 757337

    91. Benzoic Acid, P-(butylamino)-, 2-(dimethylamino)ethyl Ester, Monohydrochloride

    92. Tetracaine Hydrochloride [mart.]

    93. Tetracaine Hydrochloride [vandf]

    94. Ncgc00016049-07

    95. Ncgc00094458-01

    96. Ncgc00094458-02

    97. Ncgc00094458-03

    98. Ncgc00094458-04

    99. Ncgc00094458-05

    100. Ncgc00261896-01

    101. Tetracaine Hydrochloride [usp-rs]

    102. Tetracaine Hydrochloride [who-dd]

    103. Tetracaine Hydrochloride [who-ip]

    104. 53762-93-9

    105. Amethocaine Hydrochloride [who-ip]

    106. Db-042341

    107. Eu-0101211

    108. Ft-0603346

    109. Ft-0674941

    110. Sw196411-3

    111. T1688

    112. Tetracaine Hydrochloride [green Book]

    113. Tetracaine Hydrochloride [orange Book]

    114. D00741

    115. T 7508

    116. Tetracaine Hydrochloride [ep Monograph]

    117. Tetracaine Hydrochloride [usp Monograph]

    118. Tetracaini Hydrochloridum [who-ip Latin]

    119. 136t470

    120. A807078

    121. Kovanaze Component Tetracaine Hydrochloride

    122. Tetracaine Hydrochloride, Sigma Reference Standard

    123. Q-201806

    124. Sr-01000075240-1

    125. Sr-01000075240-6

    126. Q27262597

    127. Tetracaine Hydrochloride Component Of Kovanaze

    128. Tetracaine Hydrochloride, Meets Usp Testing Specifications

    129. Tetracaine Hydrochloride 1.0 Mg/ml In Acetonitrile (as Free Base)

    130. Tetracaine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    131. Benzoic Acid, 4-(butylamino)-, 2-(dimethylamino)ethyl Ester,monohydrochloride

    132. Tetracaine For System Suitability, European Pharmacopoeia (ep) Reference Standard

    133. Tetracaine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

    134. Tetracaine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 300.82 g/mol
    Molecular Formula C15H25ClN2O2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count9
    Exact Mass300.1604557 g/mol
    Monoisotopic Mass300.1604557 g/mol
    Topological Polar Surface Area41.6 Ų
    Heavy Atom Count20
    Formal Charge0
    Complexity249
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anesthetics, Local

    Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)

    4.2 FDA Pharmacological Classification
    4.2.1 Pharmacological Classes
    Esters [CS]; Local Anesthesia [PE]; Ester Local Anesthetic [EPC]

    API Reference Price

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MAHARASHTRA","supplier":"ALCON BIOSCIENCES","supplierCountry":"INDIA","foreign_port":"ZURICH","customer":"TO ORDER.","customerCountry":"SWITZERLAND","quantity":"6.00","actualQuantity":"6","unit":"KGS","unitRateFc":"500","totalValueFC":"2705.1","currency":"USD","unitRateINR":37439.5,"date":"11-Jul-2024","totalValueINR":"224637","totalValueInUsd":"2705.1","indian_port":"Bombay Air","hs_no":"29163190","bill_no":"2358312","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"112,, MARINE CHAMBERS,, MUMBAI. MAHARASHTRA","customerAddress":""}]
    18-Jan-2021
    11-Jul-2024
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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