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Synopsis

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Chemistry

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Also known as: 78287-27-1, 7-ethyl camptothecin, (s)-4,11-diethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione, Sn 22, Sn-22, Lpy7fe51iw
Molecular Formula
C22H20N2O4
Molecular Weight
376.4  g/mol
InChI Key
MYQKIWCVEPUPIL-QFIPXVFZSA-N
FDA UNII
LPY7FE51IW

SN-22
1 2D Structure

SN-22

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(19S)-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
2.1.2 InChI
InChI=1S/C22H20N2O4/c1-3-12-13-7-5-6-8-17(13)23-19-14(12)10-24-18(19)9-16-15(20(24)25)11-28-21(26)22(16,27)4-2/h5-9,27H,3-4,10-11H2,1-2H3/t22-/m0/s1
2.1.3 InChI Key
MYQKIWCVEPUPIL-QFIPXVFZSA-N
2.1.4 Canonical SMILES
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=CC=CC=C51
2.1.5 Isomeric SMILES
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=CC=CC=C51
2.2 Other Identifiers
2.2.1 UNII
LPY7FE51IW
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Sn 22

2. Sn-22

2.3.2 Depositor-Supplied Synonyms

1. 78287-27-1

2. 7-ethyl Camptothecin

3. (s)-4,11-diethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione

4. Sn 22

5. Sn-22

6. Lpy7fe51iw

7. 7-ethyl-20(s)-camptothecin

8. (19s)-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione

9. (4s)-4,11-diethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione

10. (s)-4,11-diethyl-4-hydroxy-1h-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione

11. (19s)-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione

12. 1h-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione, 4,11-diethyl-4-hydroxy-, (s)-

13. Mfcd06657922

14. 7-ethyl-camptothecin

15. Unii-lpy7fe51iw

16. Schembl1005149

17. 7-ethylcamptothecin, Aldrichcpr

18. Dtxsid60228960

19. Chebi:191009

20. Myqkiwcvepupil-qfipxvfzsa-n

21. Amy24894

22. Hy-n2108

23. Bdbm50092821

24. S5111

25. Akos015909654

26. Ac-1267

27. Ccg-268367

28. Cs-o-30626

29. Ks-5291

30. Pd088243

31. 7-ethylcamptothecin [usp Impurity]

32. Cs-0018629

33. E0781

34. H11443

35. A865061

36. J-502459

37. (19s)-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0?,??.0?,?.0??,??]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione

38. (r)-4-ethyl-4-methyl-1,4a,12,13a-tetrahydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione

39. (s)-4,11-diethyl-4,9-dihydroxy-1,5,5a,12-tetrahydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione

40. (s)-4,11-diethyl-4-hydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione

41. (s)-4,11-diethyl-4-hydroxy-1h-pyrano(3,4:6,7)indolizino(1,2-b)quin Oline-3,14(4h,12h)-dione

42. (s)-4,11-diethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione (7-ethyl-20(s)-camptothecin)

43. 1h-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione, 4,11-diethyl-4-hydroxy-, (4s)-

44. 4,11-diethyl-4,9-dihydroxy-(4s)-3,4,12,14-tetrahydro-1h-pyrano[3'',4'':6,7]indolizino[1,2-b]quinoline-3,14-dione

45. 4,11-diethyl-4,9-dihydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione

46. 4,11-diethyl-4,9-dihydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione (sn-38)

47. 4,11-diethyl-4-hydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione

2.3.3 Other Synonyms

1. Sn-22

2. Sn 22

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 376.4 g/mol
Molecular Formula C22H20N2O4
XLogP31.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area79.7
Heavy Atom Count28
Formal Charge0
Complexity787
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 78287-27-1 / SN-22 API manufacturers, exporters & distributors?

SN-22 manufacturers, exporters & distributors 1

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Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred SN-22 manufacturer or SN-22 supplier.

PharmaCompass also assists you with knowing the SN-22 API Price utilized in the formulation of products. SN-22 API Price is not always fixed or binding as the SN-22 Price is obtained through a variety of data sources. The SN-22 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

SN-22

Synonyms

78287-27-1, 7-ethyl camptothecin, (s)-4,11-diethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione, Sn 22, Lpy7fe51iw, 7-ethyl-20(s)-camptothecin

Cas Number

78287-27-1

Unique Ingredient Identifier (UNII)

LPY7FE51IW

SN 22 Manufacturers

A SN 22 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of SN 22, including repackagers and relabelers. The FDA regulates SN 22 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. SN 22 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of SN 22 manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

SN 22 Suppliers

A SN 22 supplier is an individual or a company that provides SN 22 active pharmaceutical ingredient (API) or SN 22 finished formulations upon request. The SN 22 suppliers may include SN 22 API manufacturers, exporters, distributors and traders.

click here to find a list of SN 22 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

SN 22 GMP

SN 22 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of SN 22 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right SN 22 GMP manufacturer or SN 22 GMP API supplier for your needs.

SN 22 CoA

A SN 22 CoA (Certificate of Analysis) is a formal document that attests to SN 22's compliance with SN 22 specifications and serves as a tool for batch-level quality control.

SN 22 CoA mostly includes findings from lab analyses of a specific batch. For each SN 22 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

SN 22 may be tested according to a variety of international standards, such as European Pharmacopoeia (SN 22 EP), SN 22 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (SN 22 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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