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Chemistry

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Also known as: 2260969-36-4, Selnoflast [inn], T23rpa8wa2, Rg6418, Ro7486967, Ro-7486967
Molecular Formula
C20H29N3O3S
Molecular Weight
391.5  g/mol
InChI Key
OHIFQOUPTWBQLE-UHFFFAOYSA-N
FDA UNII
T23RPA8WA2

Selnoflast
Selnoflast is a small molecule drug. The usage of the INN stem '-noflast' in the name indicates that Selnoflast is a inflammasome protein NLRP3 inhibitor. Selnoflast is under investigation in clinical trial NCT05924243 (A Study to Investigate The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7486967 in Participants With Early Idiopathic Parkinson's Disease.). Selnoflast has a monoisotopic molecular weight of 391.19 Da.
1 2D Structure

Selnoflast

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-(1-ethylpiperidin-4-yl)sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea
2.1.2 InChI
InChI=1S/C20H29N3O3S/c1-2-23-11-9-16(10-12-23)27(25,26)22-20(24)21-19-17-7-3-5-14(17)13-15-6-4-8-18(15)19/h13,16H,2-12H2,1H3,(H2,21,22,24)
2.1.3 InChI Key
OHIFQOUPTWBQLE-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
T23RPA8WA2
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 2260969-36-4

2. Selnoflast [inn]

3. T23rpa8wa2

4. Rg6418

5. Ro7486967

6. Ro-7486967

7. Rg-6418

8. Example 6 [wo2019008025a1]

9. 1-(1-ethylpiperidin-4-yl)sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea

10. 1-ethyl-n-(((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino)carbonyl)-4-piperidinesulfonamide

11. 4-piperidinesulfonamide, 1-ethyl-n-(((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino)carbonyl)-

12. Example 6 (wo2019008025a1)

13. Refchem:182333

14. Selnoflast [usan]

15. Selnoflast [usan:inn]

16. Unii-t23rpa8wa2

17. Who 11687

18. 1-ethyl-n-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)piperidine-4-sulfonamide

19. 1-ethyl-n-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]piperidine-4-sulfonamide

20. Selnoflast (usan/inn)

21. Orb1688251

22. Chembl5095423

23. Schembl20634304

24. Gtpl12173

25. Bdbm733146

26. Glxc-27711

27. Ex-a9807

28. Mfcd34579587

29. Us20250115591, Example 6

30. Da-57784

31. Ms-26540

32. Sy347075

33. Hy-132831

34. Cs-0204138

35. D12422

36. G18544

37. 4-piperidinesulfonamide,1-ethyl-n-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-

2.4 Create Date
2019-03-16
3 Chemical and Physical Properties
Molecular Weight 391.5 g/mol
Molecular Formula C20H29N3O3S
XLogP33.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area86.9
Heavy Atom Count27
Formal Charge0
Complexity619
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 2260969-36-4 / Selnoflast API manufacturers, exporters & distributors?

Selnoflast manufacturers, exporters & distributors 1

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Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Selnoflast manufacturer or Selnoflast supplier.

API | Excipient name

Selnoflast

Synonyms

2260969-36-4, Selnoflast [inn], T23rpa8wa2, Rg6418, Ro7486967, Ro-7486967

Cas Number

2260969-36-4

Unique Ingredient Identifier (UNII)

T23RPA8WA2

About Selnoflast

Selnoflast is a small molecule drug. The usage of the INN stem '-noflast' in the name indicates that Selnoflast is a inflammasome protein NLRP3 inhibitor. Selnoflast is under investigation in clinical trial NCT05924243 (A Study to Investigate The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7486967 in Participants With Early Idiopathic Parkinson's Disease.). Selnoflast has a monoisotopic molecular weight of 391.19 Da.

Selnoflast Manufacturers

A Selnoflast manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Selnoflast, including repackagers and relabelers. The FDA regulates Selnoflast manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Selnoflast API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Selnoflast Suppliers

A Selnoflast supplier is an individual or a company that provides Selnoflast active pharmaceutical ingredient (API) or Selnoflast finished formulations upon request. The Selnoflast suppliers may include Selnoflast API manufacturers, exporters, distributors and traders.

Selnoflast GMP

Selnoflast Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Selnoflast GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Selnoflast GMP manufacturer or Selnoflast GMP API supplier for your needs.

Selnoflast CoA

A Selnoflast CoA (Certificate of Analysis) is a formal document that attests to Selnoflast's compliance with Selnoflast specifications and serves as a tool for batch-level quality control.

Selnoflast CoA mostly includes findings from lab analyses of a specific batch. For each Selnoflast CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Selnoflast may be tested according to a variety of international standards, such as European Pharmacopoeia (Selnoflast EP), Selnoflast JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Selnoflast USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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