Trusted Global CDMO Partner Delivering End-to-End Pharma Manufacturing & Development Solutions.

Contact Supplier

Evonik Health Care is the innovation hub for leading life science companies

ACCESS ALL DATA
CHEMISTRY
Discover Molecule Insights

DEVELOPMENTS

1 Drugs in Development

1 Drugs in Development

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

1PROSPECTS

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

API/FDF Prices: Book a Demo

API REF. PRICE (USD/KG)

$ 0

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Regulatory FDF Prices

MARKET PLACE

API

FDF

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 2260969-36-4, Selnoflast [inn], T23rpa8wa2, Rg6418, Ro7486967, Ro-7486967

Molecular Formula

C₂₀H₂₉N₃O₃S

Molecular Weight

391.5 g/mol

InChI Key

OHIFQOUPTWBQLE-UHFFFAOYSA-N

FDA UNII

T23RPA8WA2

Selnoflast is a small molecule drug. The usage of the INN stem '-noflast' in the name indicates that Selnoflast is a inflammasome protein NLRP3 inhibitor. Selnoflast is under investigation in clinical trial NCT05924243 (A Study to Investigate The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7486967 in Participants With Early Idiopathic Parkinson's Disease.). Selnoflast has a monoisotopic molecular weight of 391.19 Da.

1 2D Structure

Selnoflast

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-(1-ethylpiperidin-4-yl)sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea

2.1.2 InChI

InChI=1S/C20H29N3O3S/c1-2-23-11-9-16(10-12-23)27(25,26)22-20(24)21-19-17-7-3-5-14(17)13-15-6-4-8-18(15)19/h13,16H,2-12H2,1H3,(H2,21,22,24)

2.1.3 InChI Key

OHIFQOUPTWBQLE-UHFFFAOYSA-N

2.2 Other Identifiers

2.2.1 UNII

T23RPA8WA2

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 2260969-36-4

2. Selnoflast [inn]

3. T23rpa8wa2

4. Rg6418

5. Ro7486967

6. Ro-7486967

7. Rg-6418

8. Example 6 [wo2019008025a1]

9. 1-(1-ethylpiperidin-4-yl)sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea

10. 1-ethyl-n-(((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino)carbonyl)-4-piperidinesulfonamide

11. 4-piperidinesulfonamide, 1-ethyl-n-(((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino)carbonyl)-

12. Example 6 (wo2019008025a1)

13. Refchem:182333

14. Selnoflast [usan]

15. Selnoflast [usan:inn]

16. Unii-t23rpa8wa2

17. Who 11687

18. 1-ethyl-n-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)piperidine-4-sulfonamide

19. 1-ethyl-n-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]piperidine-4-sulfonamide

20. Selnoflast (usan/inn)

21. Orb1688251

22. Chembl5095423

23. Schembl20634304

24. Gtpl12173

25. Bdbm733146

26. Glxc-27711

27. Ex-a9807

28. Mfcd34579587

29. Us20250115591, Example 6

30. Da-57784

31. Ms-26540

32. Sy347075

33. Hy-132831

34. Cs-0204138

35. D12422

36. G18544

37. 4-piperidinesulfonamide,1-ethyl-n-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-

2.4 Create Date

2019-03-16

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₂₉N₃O₃S
Molecular Weight	391.5 g/mol
XLogP3	3.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	Da
Monoisotopic Mass	Da
Topological Polar Surface Area	86.9
Heavy Atom Count	27
Formal Charge	0
Complexity	619
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

Drugs in Development

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

ABOUT THIS PAGE

Privacy policy
Terms and conditions
Disclaimers
Product listings are provided for informational purposes only. We do not supply or sell any products. Any products that may be covered by patent(s) are supplied solely for uses permitted under Section 107A of the Indian Patents Act and not for commercial sale.

Find Selnoflast manufacturers, exporters & distributors on PharmaCompass

Selnoflast

ACCESS ALL DATA

CHEMISTRY

Discover Molecule Insights

DEVELOPMENTS

1 Drugs in Development

ACTIVE PHARMA INGREDIENTS

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

FINISHED DOSAGE FORMULATIONS

1PROSPECTS

1DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

API REF. PRICE (USD/KG)

$ 0

GLOBAL SALES INFORMATION

MARKET PLACE

DIGITAL CONTENT

What are you looking for?