Find Sarizotan manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Sarizotan [inn], 351862-32-3, 467lu0ucuw, Emd-77697, 1-[(2r)-3,4-dihydro-2h-chromen-2-yl]-n-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]methanamine, 1-(5-(4-fluorophenyl)pyridin-3-yl)-n-((2r)-3,4,4a,8a-tetrahydro-2h-chromen-2-ylmethyl)methanamine
Molecular Formula
C22H21FN2O
Molecular Weight
348.4  g/mol
InChI Key
HKFMQJUJWSFOLY-OAQYLSRUSA-N
FDA UNII
467LU0UCUW

Sarizotan
1 2D Structure

Sarizotan

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[(2R)-3,4-dihydro-2H-chromen-2-yl]-N-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]methanamine
2.1.2 InChI
InChI=1S/C22H21FN2O/c23-20-8-5-17(6-9-20)19-11-16(12-24-14-19)13-25-15-21-10-7-18-3-1-2-4-22(18)26-21/h1-6,8-9,11-12,14,21,25H,7,10,13,15H2/t21-/m1/s1
2.1.3 InChI Key
HKFMQJUJWSFOLY-OAQYLSRUSA-N
2.1.4 Canonical SMILES
C1CC2=CC=CC=C2OC1CNCC3=CC(=CN=C3)C4=CC=C(C=C4)F
2.1.5 Isomeric SMILES
C1CC2=CC=CC=C2O[C@H]1CNCC3=CC(=CN=C3)C4=CC=C(C=C4)F
2.2 Other Identifiers
2.2.1 UNII
467LU0UCUW
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Emd128130

2. Sarizotan Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. Sarizotan [inn]

2. 351862-32-3

3. 467lu0ucuw

4. Emd-77697

5. 1-[(2r)-3,4-dihydro-2h-chromen-2-yl]-n-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]methanamine

6. 1-(5-(4-fluorophenyl)pyridin-3-yl)-n-((2r)-3,4,4a,8a-tetrahydro-2h-chromen-2-ylmethyl)methanamine

7. 3-pyridinemethanamine, 5-(4-fluorophenyl)-n-(((2r)-3,4,4a,8a-tetrahydro-2h-1-benzopyran-2-yl)methyl)-

8. Unii-467lu0ucuw

9. (-)-(r)-n-(3,4-dihydro-2h-1-benzofuran-2-ylmethyl)-n-[5-(4-fluorophenyl)-3-pyridylmethyl]amine

10. 195068-07-6

11. Sarizotan [mi]

12. Sarizotan [who-dd]

13. Schembl120080

14. Chembl220808

15. Zinc21067

16. Bdbm50027256

17. Db06454

18. Hy-100820

19. Cs-0020461

20. A1-26903

21. Q7424144

22. (r)-(+)-2-[5-(4-fluorphenyl)-3-pyridylmethylaminomethyl]-chromane

23. (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman

24. (r)-1-(chroman-2-yl)-n-((5-(4-fluorophenyl)pyridin-3-yl)methyl)methanamine

25. 3-pyridinemethanamine, N-(((2r)-3,4-dihydro-2h-1-benzopyran-2-yl)methyl)-5-(4-fluorophenyl)-

2.4 Create Date
2006-07-28
3 Chemical and Physical Properties
Molecular Weight 348.4 g/mol
Molecular Formula C22H21FN2O
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass348.16379146 g/mol
Monoisotopic Mass348.16379146 g/mol
Topological Polar Surface Area34.2 Ų
Heavy Atom Count26
Formal Charge0
Complexity426
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Investigated for use/treatment in schizophrenia and schizoaffective disorders and parkinson's disease.


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Looking for 351862-32-3 / Sarizotan API manufacturers, exporters & distributors?

Sarizotan manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Sarizotan API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sarizotan manufacturer or Sarizotan supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Sarizotan manufacturer or Sarizotan supplier.

PharmaCompass also assists you with knowing the Sarizotan API Price utilized in the formulation of products. Sarizotan API Price is not always fixed or binding as the Sarizotan Price is obtained through a variety of data sources. The Sarizotan Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Sarizotan

Synonyms

Sarizotan [inn], 351862-32-3, 467lu0ucuw, Emd-77697, 1-[(2r)-3,4-dihydro-2h-chromen-2-yl]-n-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]methanamine, 1-(5-(4-fluorophenyl)pyridin-3-yl)-n-((2r)-3,4,4a,8a-tetrahydro-2h-chromen-2-ylmethyl)methanamine

Cas Number

351862-32-3

Unique Ingredient Identifier (UNII)

467LU0UCUW

Sarizotan Manufacturers

A Sarizotan manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sarizotan, including repackagers and relabelers. The FDA regulates Sarizotan manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sarizotan API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sarizotan Suppliers

A Sarizotan supplier is an individual or a company that provides Sarizotan active pharmaceutical ingredient (API) or Sarizotan finished formulations upon request. The Sarizotan suppliers may include Sarizotan API manufacturers, exporters, distributors and traders.

Sarizotan GMP

Sarizotan Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sarizotan GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sarizotan GMP manufacturer or Sarizotan GMP API supplier for your needs.

Sarizotan CoA

A Sarizotan CoA (Certificate of Analysis) is a formal document that attests to Sarizotan's compliance with Sarizotan specifications and serves as a tool for batch-level quality control.

Sarizotan CoA mostly includes findings from lab analyses of a specific batch. For each Sarizotan CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sarizotan may be tested according to a variety of international standards, such as European Pharmacopoeia (Sarizotan EP), Sarizotan JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sarizotan USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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