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Chemistry

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Also known as: 20874-52-6, Beta-d-galactopyranoside, (3beta,4alpha,16alpha)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-o-beta-d-glucopyranosyl-, Ur635j3f00, (2s,3r,4s,5s,6r)-2-[(2r,3r,4s,5s,6r)-3,5-dihydroxy-2-[[(1s,2r,4s,5r,8r,9r,10s,13s,14r,17s,18r)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracos-15-en-10-yl]oxy]-6-methyloxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol, Saikosaponins, Saikosaponin d from bupleurum falcatnum
Molecular Formula
C42H68O13
Molecular Weight
781.0  g/mol
InChI Key
KYWSCMDFVARMPN-LCSVLAELSA-N
FDA UNII
UR635J3F00

Saikosaponin D
saikosaponin d is a natural product found in Bupleurum kunmingense, Bupleurum kaoi, and other organisms with data available.
1 2D Structure

Saikosaponin D

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-3,5-dihydroxy-2-[[(1S,2R,4S,5R,8R,9R,10S,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracos-15-en-10-yl]oxy]-6-methyloxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
2.1.2 InChI
InChI=1S/C42H68O13/c1-21-28(46)33(55-34-31(49)30(48)29(47)22(18-43)53-34)32(50)35(52-21)54-27-10-11-37(4)23(38(27,5)19-44)8-12-39(6)24(37)9-13-42-25-16-36(2,3)14-15-41(25,20-51-42)26(45)17-40(39,42)7/h9,13,21-35,43-50H,8,10-12,14-20H2,1-7H3/t21-,22-,23-,24-,25-,26-,27+,28+,29-,30+,31-,32-,33+,34+,35+,37+,38+,39-,40+,41-,42+/m1/s1
2.1.3 InChI Key
KYWSCMDFVARMPN-LCSVLAELSA-N
2.1.4 Canonical SMILES
CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC56C4(CC(C7(C5CC(CC7)(C)C)CO6)O)C)C)C)O)OC8C(C(C(C(O8)CO)O)O)O)O
2.1.5 Isomeric SMILES
C[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]2CC[C@]3([C@H]([C@]2(C)CO)CC[C@@]4([C@@H]3C=C[C@@]56[C@]4(C[C@H]([C@@]7([C@H]5CC(CC7)(C)C)CO6)O)C)C)C)O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
UR635J3F00
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Saikosaponin A

2. Saikosaponin B

3. Saikosaponin B1

4. Saikosaponin B2

5. Saikosaponin B3

6. Saikosaponin B4

7. Saikosaponin C

8. Saikosaponin K

9. Saikosaponin L

10. Saikosaponins

2.3.2 Depositor-Supplied Synonyms

1. 20874-52-6

2. Beta-d-galactopyranoside, (3beta,4alpha,16alpha)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-o-beta-d-glucopyranosyl-

3. Ur635j3f00

4. (2s,3r,4s,5s,6r)-2-[(2r,3r,4s,5s,6r)-3,5-dihydroxy-2-[[(1s,2r,4s,5r,8r,9r,10s,13s,14r,17s,18r)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracos-15-en-10-yl]oxy]-6-methyloxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

5. Saikosaponins

6. Saikosaponin D From Bupleurum Falcatnum

7. Schembl929710

8. Unii-ur635j3f00

9. Chembl3613719

10. Dtxsid301317467

11. (2s,3r,4s,5s,6r)-2-[(2r,3r,4s,5s,6r)-3,5-dihydroxy-2-[hydroxy-(hydroxymethyl)-hexamethyl-[?]yl]oxy-6-methyl-tetrahydropyran-4-yl]oxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol

12. Hy-n0250

13. Mfcd09028095

14. S5454

15. Akos016034270

16. Zinc247647500

17. Ccg-270465

18. Cs-0008281

19. N1887

20. Q-100262

21. Q27291219

22. .beta.-d-galactopyranoside, (3.beta.,4.alpha.,16.alpha.)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-o-.beta.-d-glucopyranosyl-

23. Beta-d-galactopyranoside, (3beta,4alpha,16alpha)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-o-beta-d-glucopyranosyl

2.4 Create Date
2005-08-01
3 Chemical and Physical Properties
Molecular Weight 781.0 g/mol
Molecular Formula C42H68O13
XLogP32.5
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count13
Rotatable Bond Count6
Exact Mass780.46599222 g/mol
Monoisotopic Mass780.46599222 g/mol
Topological Polar Surface Area208 Ų
Heavy Atom Count55
Formal Charge0
Complexity1490
Isotope Atom Count0
Defined Atom Stereocenter Count21
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


Antiviral Agents

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)


Antineoplastic Agents, Phytogenic

Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity. (See all compounds classified as Antineoplastic Agents, Phytogenic.)


Immunosuppressive Agents

Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. (See all compounds classified as Immunosuppressive Agents.)


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ABOUT THIS PAGE

Looking for 20874-52-6 / Saikosaponin D API manufacturers, exporters & distributors?

Saikosaponin D manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Saikosaponin D API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Saikosaponin D manufacturer or Saikosaponin D supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Saikosaponin D manufacturer or Saikosaponin D supplier.

PharmaCompass also assists you with knowing the Saikosaponin D API Price utilized in the formulation of products. Saikosaponin D API Price is not always fixed or binding as the Saikosaponin D Price is obtained through a variety of data sources. The Saikosaponin D Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Saikosaponin D

Synonyms

20874-52-6, Beta-d-galactopyranoside, (3beta,4alpha,16alpha)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-o-beta-d-glucopyranosyl-, Ur635j3f00, (2s,3r,4s,5s,6r)-2-[(2r,3r,4s,5s,6r)-3,5-dihydroxy-2-[[(1s,2r,4s,5r,8r,9r,10s,13s,14r,17s,18r)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracos-15-en-10-yl]oxy]-6-methyloxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol, Saikosaponins, Saikosaponin d from bupleurum falcatnum

Cas Number

20874-52-6

Unique Ingredient Identifier (UNII)

UR635J3F00

About Saikosaponin D

saikosaponin d is a natural product found in Bupleurum kunmingense, Bupleurum kaoi, and other organisms with data available.

Saikosaponin D Manufacturers

A Saikosaponin D manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Saikosaponin D, including repackagers and relabelers. The FDA regulates Saikosaponin D manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Saikosaponin D API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Saikosaponin D Suppliers

A Saikosaponin D supplier is an individual or a company that provides Saikosaponin D active pharmaceutical ingredient (API) or Saikosaponin D finished formulations upon request. The Saikosaponin D suppliers may include Saikosaponin D API manufacturers, exporters, distributors and traders.

Saikosaponin D GMP

Saikosaponin D Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Saikosaponin D GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Saikosaponin D GMP manufacturer or Saikosaponin D GMP API supplier for your needs.

Saikosaponin D CoA

A Saikosaponin D CoA (Certificate of Analysis) is a formal document that attests to Saikosaponin D's compliance with Saikosaponin D specifications and serves as a tool for batch-level quality control.

Saikosaponin D CoA mostly includes findings from lab analyses of a specific batch. For each Saikosaponin D CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Saikosaponin D may be tested according to a variety of international standards, such as European Pharmacopoeia (Saikosaponin D EP), Saikosaponin D JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Saikosaponin D USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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