Find Betamethasone Dipropionate manufacturers, exporters & distributors on PharmaCompass

Question

Looking for 5593-20-4 / Betamethasone Dipropionate API manufacturers, exporters & distributors?

API | Excipient name

Betamethasone Dipropionate

Synonyms

Diprolene, Diprosone, 5593-20-4, Maxivate, Diprolene af, Alphatrex

Cas Number

5593-20-4

Unique Ingredient Identifier (UNII)

826Y60901U

About Betamethasone Dipropionate

Betamethasone Dipropionate is the 17,21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

score 82 · Accepted Answer

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Molecular Formula	C₂₈H₃₇FO₇
Molecular Weight	504.6 g/mol
XLogP3	3.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	8
Exact Mass	504.25233168 g/mol
Monoisotopic Mass	504.25233168 g/mol
Topological Polar Surface Area	107 Å²
Heavy Atom Count	36
Formal Charge	0
Complexity	1050
Isotope Atom Count	0
Defined Atom Stereocenter Count	8
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

1 of 6
Drug Name	Betamethasone dipropionate
PubMed Health	Betamethasone Dipropionate (On the skin)
Drug Classes	Corticosteroid, Strong
Drug Label	Betamethasone Dipropionate Lotion USP 0.05% (Augmented) contains betamethasone dipropionate, USP, a synthetic adrenocorticosteroid, for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a sli...
Active Ingredient	Betamethasone dipropionate
Dosage Form	Lotion; Ointment, augmented; Ointment; Lotion, augmented; Cream; Cream, augmented; Gel, augmented
Route	Topical
Strength	eq 0.05% base
Market Status	Prescription
Company	Glenmark Generics; Fougera Pharms; Actavis Mid Atlantic; Teva; Perrigo New York; Taro; Fougera; Tolmar

2 of 6
Drug Name	Diprolene
PubMed Health	Betamethasone Dipropionate, Augmented (On the skin)
Drug Classes	Corticosteroid, Very Strong
Drug Label	DIPROLENE (augmented betamethasone dipropionate) Ointment contains betamethasone dipropionate USP, a synthetic adrenocorticosteroid, for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a...
Active Ingredient	Betamethasone dipropionate
Dosage Form	Ointment, augmented; Lotion, augmented
Route	Topical
Strength	eq 0.05% base
Market Status	Prescription
Company	Merck Sharp Dohme

3 of 6
Drug Name	Diprolene af
PubMed Health	Betamethasone Dipropionate, Augmented (On the skin)
Drug Classes	Corticosteroid, Very Strong
Drug Label	DIPROLENE AF Cream 0.05% contains betamethasone dipropionate USP, a synthetic adrenocorticosteroid, for dermatologic use in an emollient base. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a slight degre...
Active Ingredient	Betamethasone dipropionate
Dosage Form	Cream, augmented
Route	Topical
Strength	eq 0.05% base
Market Status	Prescription
Company	Merck Sharp Dohme

4 of 6
Drug Name	Betamethasone dipropionate
PubMed Health	Betamethasone Dipropionate (On the skin)
Drug Classes	Corticosteroid, Strong
Drug Label	Betamethasone Dipropionate Lotion USP 0.05% (Augmented) contains betamethasone dipropionate, USP, a synthetic adrenocorticosteroid, for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a sli...
Active Ingredient	Betamethasone dipropionate
Dosage Form	Lotion; Ointment, augmented; Ointment; Lotion, augmented; Cream; Cream, augmented; Gel, augmented
Route	Topical
Strength	eq 0.05% base
Market Status	Prescription
Company	Glenmark Generics; Fougera Pharms; Actavis Mid Atlantic; Teva; Perrigo New York; Taro; Fougera; Tolmar

Find Betamethasone Dipropionate manufacturers, exporters & distributors on PharmaCompass

ACCESS ALL DATA

CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

60 API Suppliers

16 USDMF

8 CEP/COS

6 JDMF

10 EU WC

2 KDMF

12 NDC API

36 Listed Suppliers

DEVELOPMENTS

18 Drugs in Development

FINISHED DOSAGE FORMULATIONS

378 FDF Dossiers

80 FDA Orange Book

217 Europe

3 Canada

46 Australia

9 South Africa

23 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

OINTMENT, AUGMENTED;TOPICAL - EQ 0.05% BASE

CREAM;TOPICAL - EQ 0.05% BASE;1% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

CREAM;TOPICAL - EQ 0.05% BASE

OINTMENT;TOPICAL - EQ 0.05% BASE

CREAM, AUGMENTED;TOPICAL - EQ 0.05% BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

LOTION, AUGMENTED;TOPICAL - EQ 0.05% BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

OINTMENT;TOPICAL - 0.064%;0.005%

SUSPENSION;TOPICAL - 0.064%;0.005%

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc

2 SPI Pharma

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7 Nanjing Well Pharmaceutical

3 Kirsch Pharma

1 Dr. Paul Lohmann GmbH & Co. KGaA

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11 BASF

1 Clariant

4 Corel Pharma Chem

2 Finar

4 Lubrizol Life Science Health

11 Roquette

1 Seppic

2 Shandong Focus Biotechnology Co., Ltd

1 Shijiazhuang Huaxu Pharmaceutical

1 Valens Pharmachem

1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

25 Topical

13 Film Formers & Plasticizers

9 Parenteral

8 Emulsifying Agents

6 Solubilizers

6 Thickeners and Stabilizers

4 Coating Systems & Additives

4 Fillers, Diluents & Binders

4 Taste Masking

4 Lubricants & Glidants

3 Direct Compression

3 Surfactant & Foaming Agents

2 Granulation

2 Controlled & Modified Release

2 Chewable & Orodispersible Aids

1 API Stability Enhancers

1 Soft Gelatin

1 Rheology Modifiers

1 Co-Processed Excipients

DIGITAL CONTENT

50 News #PharmaBuzz

GLOBAL SALES INFORMATION

31 US Medicaid Prescriptions

16 Regulatory FDF Prices

16 Annual Reports

MARKET PLACE

23 APIs

1 FDF Dossiers

CREAM;TOPICAL - EQ 0.05% BASE;1% Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons

CREAM, AUGMENTED;TOPICAL - EQ 0.05% BASE Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons

LOTION, AUGMENTED;TOPICAL - EQ 0.05% BASE Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons