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Chemistry

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Also known as: Resiquimod sulfate (usan), 2762439-40-5, Resiquimod sulfate [usan], Eik1001 sulfate, Eik-1001 sulfate, C8fkis4p1n
Molecular Formula
C17H24N4O6S
Molecular Weight
412.5  g/mol
InChI Key
DGMINEMBFOEPHX-UHFFFAOYSA-N
FDA UNII
C8FKIS4P1N

Resiquimod Sulfate
Resiquimod Sulfate is the sulfate salt form of resiquimod, a toll-like receptor type 7 and 8 (TLR7/8) agonist, with potential immunostimulating and antineoplastic activities. Upon administration, resiquimod targets, binds to and activates TLR7 and 8, thereby activating TLR7/8-mediated pathways. This stimulates the maturation and activation of antigen-presenting cells (APCs), including dendritic cells (DCs). Activation of DCs results in the production of pro-inflammatory cytokines, and the activation of cytotoxic T-lymphocyte (CTL)- and B-lymphocyte-mediated immune responses. This may lead to tumor cell lysis. TLR7 and 8, members of the TLR family, play fundamental roles in the activation of the innate immune system, myeloid cell responses and tumor antigen presentation.
1 2D Structure

Resiquimod Sulfate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[4-amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol;sulfuric acid
2.1.2 InChI
InChI=1S/C17H22N4O2.H2O4S/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18;1-5(2,3)4/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19);(H2,1,2,3,4)
2.1.3 InChI Key
DGMINEMBFOEPHX-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
C8FKIS4P1N
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Resiquimod Sulfate (usan)

2. 2762439-40-5

3. Resiquimod Sulfate [usan]

4. Eik1001 Sulfate

5. Eik-1001 Sulfate

6. C8fkis4p1n

7. Bdb001

8. Bdb 001 [who-dd]

9. Bdb-001

10. C151008135d

11. C151008135-d

12. D13051

13. 4-amino-2-(ethoxymethyl)-1-(2-hydroxisobutyl) Imidazo[4,5-c]quinoline, Sulfate (1:1)

14. 1h-imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-, Sulfate (1:1)

2.4 Create Date
2025-02-20
3 Chemical and Physical Properties
Molecular Weight 412.5 g/mol
Molecular Formula C17H24N4O6S
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area169
Heavy Atom Count28
Formal Charge0
Complexity487
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 Mechanism of Action

BDB-001 is an anti-C5RA1 monoclonal antibody activating the toll-like receptor. It has potential antineoplastic and immunostimulating activities.


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Looking for 2762439-40-5 / Resiquimod Sulfate API manufacturers, exporters & distributors?

Resiquimod Sulfate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Resiquimod Sulfate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Resiquimod Sulfate manufacturer or Resiquimod Sulfate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Resiquimod Sulfate manufacturer or Resiquimod Sulfate supplier.

API | Excipient name

Resiquimod Sulfate

Synonyms

Resiquimod sulfate (usan), 2762439-40-5, Resiquimod sulfate [usan], Eik1001 sulfate, Eik-1001 sulfate, C8fkis4p1n

Cas Number

2762439-40-5

Unique Ingredient Identifier (UNII)

C8FKIS4P1N

About Resiquimod Sulfate

Resiquimod Sulfate is the sulfate salt form of resiquimod, a toll-like receptor type 7 and 8 (TLR7/8) agonist, with potential immunostimulating and antineoplastic activities. Upon administration, resiquimod targets, binds to and activates TLR7 and 8, thereby activating TLR7/8-mediated pathways. This stimulates the maturation and activation of antigen-presenting cells (APCs), including dendritic cells (DCs). Activation of DCs results in the production of pro-inflammatory cytokines, and the activation of cytotoxic T-lymphocyte (CTL)- and B-lymphocyte-mediated immune responses. This may lead to tumor cell lysis. TLR7 and 8, members of the TLR family, play fundamental roles in the activation of the innate immune system, myeloid cell responses and tumor antigen presentation.

Resiquimod Sulfate Manufacturers

A Resiquimod Sulfate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Resiquimod Sulfate, including repackagers and relabelers. The FDA regulates Resiquimod Sulfate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Resiquimod Sulfate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Resiquimod Sulfate Suppliers

A Resiquimod Sulfate supplier is an individual or a company that provides Resiquimod Sulfate active pharmaceutical ingredient (API) or Resiquimod Sulfate finished formulations upon request. The Resiquimod Sulfate suppliers may include Resiquimod Sulfate API manufacturers, exporters, distributors and traders.

Resiquimod Sulfate GMP

Resiquimod Sulfate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Resiquimod Sulfate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Resiquimod Sulfate GMP manufacturer or Resiquimod Sulfate GMP API supplier for your needs.

Resiquimod Sulfate CoA

A Resiquimod Sulfate CoA (Certificate of Analysis) is a formal document that attests to Resiquimod Sulfate's compliance with Resiquimod Sulfate specifications and serves as a tool for batch-level quality control.

Resiquimod Sulfate CoA mostly includes findings from lab analyses of a specific batch. For each Resiquimod Sulfate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Resiquimod Sulfate may be tested according to a variety of international standards, such as European Pharmacopoeia (Resiquimod Sulfate EP), Resiquimod Sulfate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Resiquimod Sulfate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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