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Details:

Reldesemtiv (CK-2127107), is an investigational, selective, small molecule fast skeletal muscle troponin activator (FSTA) arising from Cytokinetics’ skeletal muscle contractility program.


Lead Product(s): Reldesemtiv

Therapeutic Area: Neurology Product Name: CK-2127107

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 08, 2022

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Details:

Reldesemtiv is an investigational, selective, small molecule fast skeletal muscle troponin activator (FSTA) arising from Cytokinetics’ skeletal muscle contractility program.


Lead Product(s): Reldesemtiv

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 10, 2022

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CK-2127107 (Reldesemtiv) investigational, selective, small molecule fast skeletal muscle troponin activator arising from Cytokinetics’ skeletal muscle contractility, was designed to slow rate of calcium release from regulatory troponin complex of fast skeletal muscle fibers.


Lead Product(s): Reldesemtiv

Therapeutic Area: Neurology Product Name: CK-2127107

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 16, 2022

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The primary objective of the collaboration was to advance novel therapies for diseases and medical conditions associated with muscle weakness. In addition, Astellas had an exclusive license to co-develop Cytokinetics' drug candidate CK-2127107 in certain indications.


Lead Product(s): Reldesemtiv

Therapeutic Area: Neurology Product Name: CK-2127107

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Astellas Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Termination May 03, 2021

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Cytokinetics is developing reldesemtiv, as a potential treatment for people with ALS, SMA and certain other debilitating diseases and conditions associated with skeletal muscle weakness or fatigue.


Lead Product(s): Reldesemtiv

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 04, 2020

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