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Quifenadine
Also known as: 10447-39-9, Quifenadine [inn], 1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol, 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol, W9a18rj49b, Fenkarol
Molecular Formula
C20H23NO
Molecular Weight
293.4  g/mol
InChI Key
PZMAHNDJABQWGS-UHFFFAOYSA-N
FDA UNII
W9A18RJ49B

1 2D Structure

Quifenadine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol
2.1.2 InChI
InChI=1S/C20H23NO/c22-20(17-7-3-1-4-8-17,18-9-5-2-6-10-18)19-15-21-13-11-16(19)12-14-21/h1-10,16,19,22H,11-15H2
2.1.3 InChI Key
PZMAHNDJABQWGS-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CN2CCC1C(C2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O
2.2 Other Identifiers
2.2.1 UNII
W9A18RJ49B
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Fenatin

2. Fencarol

3. Phencarol

4. Quifenadine Hydrobromide, (+-)-isomer

5. Quifenadine Hydrochloride

6. Quinuclidinyl-3-diphenylcarbinol

2.3.2 Depositor-Supplied Synonyms

1. 10447-39-9

2. Quifenadine [inn]

3. 1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol

4. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol

5. W9a18rj49b

6. Fenkarol

7. Quifenadine (inn)

8. (3-quinuclidinyl)diphenyl Carbinol Hydrochloride

9. Ncgc00160492-01

10. .alpha.,.alpha.-diphenyl-3-quinuclidinemethanol

11. {1-azabicyclo[2.2.2]octan-3-yl}diphenylmethanol

12. Quifenadino

13. Quifenadinum

14. Quifenadinum [inn-latin]

15. Quifenadino [inn-spanish]

16. Benzhydrol, Alpha-(3-quinuclidinyl)-

17. Brn 1542055

18. Unii-w9a18rj49b

19. Alpha,alpha-diphenyl-3-quinuclidinemethanol

20. Alpha,alpha-diphenyl-3-chinuclidinylmethanol

21. 1-azabicyclo[2.2.2]octane-3-methanol,a,a-diphenyl-

22. 1-azabicyclo(2.2.2)octane-3-methanol, Alpha,alpha-diphenyl-

23. 3-quinuclidinemethanol, Alpha,alpha-diphenyl-

24. Fencarol [as Hydrochloride]

25. Dsstox_cid_26187

26. Dsstox_rid_81418

27. Dsstox_gsid_46187

28. Oprea1_250552

29. Phencarol [as Hydrochloride]

30. Phencarol; Fenatin; Fencarol

31. Quifenadine [who-dd]

32. Mls006011470

33. Schembl1813124

34. Chembl1187694

35. Dtxsid6046187

36. Schembl15292380

37. Chebi:134746

38. Bcp21301

39. Tox21_111852

40. Bbl022956

41. Mfcd01684913

42. Stk697937

43. Akos001668833

44. Db13713

45. Benzhydrol, .alpha.-(3-quinuclidinyl)-

46. Ncgc00160492-02

47. Smr002499074

48. Vs-07290

49. Cas-10447-39-9

50. D10230

51. Ab00637982-07

52. 3-quinuclidinemethanol, .alpha.,.alpha.-diphenyl-

53. Ag-205/05218021

54. Q4497981

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 293.4 g/mol
Molecular Formula C20H23NO
XLogP33.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass293.177964357 g/mol
Monoisotopic Mass293.177964357 g/mol
Topological Polar Surface Area23.5 Ų
Heavy Atom Count22
Formal Charge0
Complexity344
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Histamine Antagonists

Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only. (See all compounds classified as Histamine Antagonists.)


4.2 ATC Code

R - Respiratory system

R06 - Antihistamines for systemic use

R06A - Antihistamines for systemic use

R06AX - Other antihistamines for systemic use

R06AX31 - Quifenadine


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