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Chemistry

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Also known as: Htl22562, Htl-22562, Htl0022562, Htl-0022562, 2097085-63-5, N-((r)-3-(7-methyl-1h-indazol-5-yl)-1-oxo-1-(((s)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2'-oxo-1',2'-dihydrospiro(piperidine-4,4'-pyrido(2,3-d)(1,3)oxazine)-1-carboxamide
Molecular Formula
C40H49N11O5
Molecular Weight
763.9  g/mol
InChI Key
LIPVCPUZWNTQHV-SAIUNTKASA-N
FDA UNII
QP50ESO5RA

QP50ESO5RA
1 2D Structure

QP50ESO5RA

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-[[(2S)-1-oxo-3-piperidin-4-yl-1-(4-pyridin-4-ylpiperazin-1-yl)propan-2-yl]amino]propan-2-yl]-2-oxospiro[1H-pyrido[2,3-d][1,3]oxazine-4,4'-piperidine]-1'-carboxamide
2.1.2 InChI
InChI=1S/C40H49N11O5/c1-26-21-28(22-29-25-44-48-34(26)29)24-32(46-38(54)51-15-8-40(9-16-51)31-3-2-10-43-35(31)47-39(55)56-40)36(52)45-33(23-27-4-11-41-12-5-27)37(53)50-19-17-49(18-20-50)30-6-13-42-14-7-30/h2-3,6-7,10,13-14,21-22,25,27,32-33,41H,4-5,8-9,11-12,15-20,23-24H2,1H3,(H,44,48)(H,45,52)(H,46,54)(H,43,47,55)/t32-,33+/m1/s1
2.1.3 InChI Key
LIPVCPUZWNTQHV-SAIUNTKASA-N
2.1.4 Canonical SMILES
CC1=CC(=CC2=C1NN=C2)CC(C(=O)NC(CC3CCNCC3)C(=O)N4CCN(CC4)C5=CC=NC=C5)NC(=O)N6CCC7(CC6)C8=C(NC(=O)O7)N=CC=C8
2.1.5 Isomeric SMILES
CC1=CC(=CC2=C1NN=C2)C[C@H](C(=O)N[C@@H](CC3CCNCC3)C(=O)N4CCN(CC4)C5=CC=NC=C5)NC(=O)N6CCC7(CC6)C8=C(NC(=O)O7)N=CC=C8
2.2 Other Identifiers
2.2.1 UNII
QP50ESO5RA
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Htl22562

2. Htl-22562

3. Htl0022562

4. Htl-0022562

5. 2097085-63-5

6. N-((r)-3-(7-methyl-1h-indazol-5-yl)-1-oxo-1-(((s)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2'-oxo-1',2'-dihydrospiro(piperidine-4,4'-pyrido(2,3-d)(1,3)oxazine)-1-carboxamide

7. Unii-qp50eso5ra

8. Chembl4635331

9. Schembl18788046

10. Gtpl11113

11. Compound 8 [pmid: 32558564]

12. Hy-145353

13. Cs-0371795

14. Qlq

2.4 Create Date
2017-08-04
3 Chemical and Physical Properties
Molecular Weight 763.9 g/mol
Molecular Formula C40H49N11O5
XLogP32.1
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count10
Rotatable Bond Count9
Exact Mass763.39181371 g/mol
Monoisotopic Mass763.39181371 g/mol
Topological Polar Surface Area190 Ų
Heavy Atom Count56
Formal Charge0
Complexity1380
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 2097085-63-5 / HTL0022562 API manufacturers, exporters & distributors?

HTL0022562 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of HTL0022562 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right HTL0022562 manufacturer or HTL0022562 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred HTL0022562 manufacturer or HTL0022562 supplier.

PharmaCompass also assists you with knowing the HTL0022562 API Price utilized in the formulation of products. HTL0022562 API Price is not always fixed or binding as the HTL0022562 Price is obtained through a variety of data sources. The HTL0022562 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

HTL0022562

Synonyms

Htl22562, Htl-22562, Htl-0022562, 2097085-63-5, N-((r)-3-(7-methyl-1h-indazol-5-yl)-1-oxo-1-(((s)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2'-oxo-1',2'-dihydrospiro(piperidine-4,4'-pyrido(2,3-d)(1,3)oxazine)-1-carboxamide, Unii-qp50eso5ra

Cas Number

2097085-63-5

Unique Ingredient Identifier (UNII)

QP50ESO5RA

QP50ESO5RA Manufacturers

A QP50ESO5RA manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of QP50ESO5RA, including repackagers and relabelers. The FDA regulates QP50ESO5RA manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. QP50ESO5RA API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

QP50ESO5RA Suppliers

A QP50ESO5RA supplier is an individual or a company that provides QP50ESO5RA active pharmaceutical ingredient (API) or QP50ESO5RA finished formulations upon request. The QP50ESO5RA suppliers may include QP50ESO5RA API manufacturers, exporters, distributors and traders.

QP50ESO5RA GMP

QP50ESO5RA Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of QP50ESO5RA GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right QP50ESO5RA GMP manufacturer or QP50ESO5RA GMP API supplier for your needs.

QP50ESO5RA CoA

A QP50ESO5RA CoA (Certificate of Analysis) is a formal document that attests to QP50ESO5RA's compliance with QP50ESO5RA specifications and serves as a tool for batch-level quality control.

QP50ESO5RA CoA mostly includes findings from lab analyses of a specific batch. For each QP50ESO5RA CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

QP50ESO5RA may be tested according to a variety of international standards, such as European Pharmacopoeia (QP50ESO5RA EP), QP50ESO5RA JP (Japanese Pharmacopeia) and the US Pharmacopoeia (QP50ESO5RA USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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