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    Chemistry

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    Also known as: 496775-62-3, Revolade, Promacta, Eltrombopag (olamine), Unii-4u07f515lg, Sb-497115-gr
    Molecular Formula
    C29H36N6O6
    Molecular Weight
    564.6  g/mol
    InChI Key
    DJMJHIKGMVJYCW-UHFFFAOYSA-N
    FDA UNII
    4U07F515LG
    Eltrombopag
    Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
    1 2D Structure

    Eltrombopag

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-aminoethanol;3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid
    2.1.2 InChI
    InChI=1S/C25H22N4O4.2C2H7NO/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33;2*3-1-2-4/h4-13,28,30H,1-3H3,(H,32,33);2*4H,1-3H2
    2.1.3 InChI Key
    DJMJHIKGMVJYCW-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N=NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(=O)O)C.C(CO)N.C(CO)N
    2.2 Other Identifiers
    2.2.1 UNII
    4U07F515LG
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. (1,1'-biphenyl)-3-carboxylic Acid, 3'-((2z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol-4-ylidene)hydrazino)-2'-hydroxy-

    2. Ddl-701

    3. Eltrombopag

    4. Promacta

    5. Revolade

    6. Sb-497 115

    7. Sb-497-115

    8. Sb497115

    2.3.2 Depositor-Supplied Synonyms

    1. 496775-62-3

    2. Revolade

    3. Promacta

    4. Eltrombopag (olamine)

    5. Unii-4u07f515lg

    6. Sb-497115-gr

    7. Eltrombopag Diethanolamine Salt

    8. 496775-62-3 (olamine)

    9. Eltrombopag (as Olamine)

    10. 4u07f515lg

    11. Sb-497115gr

    12. Eltrombopag Compd With 2-aminoethanol (1:2)

    13. Eltrombopag Diethanolamine Salt;sb-497115gr

    14. (z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxyiic Acid;2-aminoethan-1-ol (1:2)

    15. 3'-((2z)-2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene)diazanyl)-2'-hydroxybiphenyl-3-carboxylic Acid Compound With 2-aminoethanol (1:2)

    16. Promacta Olamine

    17. Eltrombopagolamine

    18. Eltrombopag Olamine [usan:jan]

    19. Promacta (tn)

    20. Sb 497115gr

    21. Schembl210183

    22. Amy267

    23. Chembl3989691

    24. Schembl16207741

    25. Schembl23458316

    26. Eltrombopag Olamine (jan/usan)

    27. Eltrombopag Olamine [jan]

    28. Eltrombopag Olamine [usan]

    29. Bcp07055

    30. Eltrombopag Olamine [mart.]

    31. Eltrombopag Olamine [who-dd]

    32. Hy-15306a

    33. Mfcd22380664

    34. S2229

    35. Akos025396658

    36. Akos037515856

    37. Ccg-270074

    38. Cs-1566

    39. Sb19102

    40. Eltrombopag Olamine [orange Book]

    41. 2-aminoethan-1-ol Hemi((e)-3'-(2-(2-(3,4-dimethylphenyl)-5-methyl-3-oxo-2,3-dihydro-1h-pyrazol-4-yl)hydrazono)-2'-oxo-2',3'-dihydro-[1,1'-biphenyl]-3-carboxylate)

    42. Ac-26286

    43. Bs-17370

    44. Ft-0773802

    45. D03978

    46. A904098

    47. Q27260489

    48. Eltrombopag Compd With 2-aminoethanol (1:2) [mi]

    49. (1,1'-biphenyl)-3-carboxylic Acid, 3'-((2z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol-4-ylidene)hydrazino)-2'-hydroxy, Compound With 2-aminoethanol (1:2)

    50. (1,1'-biphenyl)-3-carboxylic Acid, 3'-((2z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol-4-ylidene)hydrazino)-2'-hydroxy-, Compound With 2-aminoethanol (1:2)

    51. (1,1'-biphenyl)-3-carboxylic Acid, 3'-(2-(1-(3,4-dimethylphenyl)-4,5-dihydro-3-methyl-5-oxo-1h-pyrazol-4-yl)diazenyl)-2'-hydroxy-, Compd. With 2-aminoethanol (1:2)

    52. 2-aminoethan-1-ol Hemi((z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate)

    53. 2-aminoethanol (e)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1h-pyrazol-4(5h)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate

    54. 2-aminoethanol;3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1h-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic Acid

    55. 3'-[(2z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid Bis-(monoethanolamine)

    56. 3'-[(2z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid Bis-(monoethanolamine)

    57. 3'-{(2z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic Acid 2-aminoethanol (1:2)

    2.4 Create Date
    2019-01-15
    3 Chemical and Physical Properties
    Molecular Weight 564.6 g/mol
    Molecular Formula C29H36N6O6
    Hydrogen Bond Donor Count7
    Hydrogen Bond Acceptor Count11
    Rotatable Bond Count7
    Exact Mass564.26963289 g/mol
    Monoisotopic Mass564.26963289 g/mol
    Topological Polar Surface Area207 Ų
    Heavy Atom Count41
    Formal Charge0
    Complexity822
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Drug and Medication Information
    4.1 Drug Indication

    Revolade is indicated for the treatment of adult patients with primary immune thrombocytopenia (ITP) who are refractory to other treatments (e. g. corticosteroids, immunoglobulins) (see sections 4. 2 and 5. 1).

    Revolade is indicated for the treatment of paediatric patients aged 1 year and above with primary immune thrombocytopenia (ITP) lasting 6 months or longer from diagnosis and who are refractory to other treatments (e. g. corticosteroids, immunoglobulins) (see sections 4. 2 and 5. 1).

    Revolade is indicated in adult patients with chronic hepatitis C virus (HCV) infection for the treatment of thrombocytopenia, where the degree of thrombocytopenia is the main factor preventing the initiation or limiting the ability to maintain optimal interferon-based therapy (see sections 4. 4 and 5. 1).

    Revolade is indicated in adult patients with acquired severe aplastic anaemia (SAA) who were either refractory to prior immunosuppressive therapy or heavily pretreated and are unsuitable for haematopoietic stem cell transplantation (see section 5. 1).

    5 Pharmacology and Biochemistry
    5.1 FDA Pharmacological Classification
    5.1.1 Pharmacological Classes
    Increased Megakaryocyte Maturation [PE]; Increased Platelet Production [PE]; Organic Anion Transporting Polypeptide 1B1 Inhibitors [MoA]; Thrombopoietin Receptor Agonist [EPC]; Thrombopoietin Receptor Agonists [MoA]; UGT1A1 Inhibitors [MoA]; UGT1A3 Inhibitors [MoA]; UGT1A4 Inhibitors [MoA]; UGT1A6 Inhibitors [MoA]; UGT1A9 Inhibitors [MoA]; UGT2B15 Inhibitors [MoA]; UGT2B7 Inhibitors [MoA]; Breast Cancer Resistance Protein Inhibitors [MoA]
    5.2 ATC Code

    B02BX05

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    API Reference Price

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K","customer":"EV ARIC PHARMACEUTICALS INC","customerCountry":"UNITED STATES","quantity":"28.00","actualQuantity":"28","unit":"KGS","unitRateFc":"175000","totalValueFC":"4868973","currency":"USD","unitRateINR":15062095.489285713,"date":"11-Mar-2025","totalValueINR":"421738673.7","totalValueInUsd":"4868973","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"8920740","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"7-2-A2, HETERO CORPORATE,, HYDERABAD-A.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1742927400,"product":"ACTIVE PHARMACEUTICAL INGREDIENTS - OTHER ORGANIC CHEMICAL COMPOUNDS - ELTROMBOPAG OLAMINE IHS","address":"SETHNA BUILDING, 4TH FLR,","city":"LINES, MUMBAI ,MAHARASHTRA","supplier":"MEGAFINE PHARMA (P) LIMITED","supplierCountry":"INDIA","foreign_port":"DUBAI","customer":"TO THE ORDER OF","customerCountry":"UNITED ARAB EMIRATES","quantity":"8.00","actualQuantity":"8","unit":"KGS","unitRateFc":"5000","totalValueFC":"39441.6","currency":"USD","unitRateINR":427041.625,"date":"26-Mar-2025","totalValueINR":"3416333","totalValueInUsd":"39441.6","indian_port":"Bombay Air","hs_no":"29349990","bill_no":"9356281","productDescription":"API","marketType":"","country":"UNITED ARAB EMIRATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"SETHNA BUILDING, 4TH FLR,, LINES, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"ELTROMBOPAG OLAMINE","year":"2021","qtr":"Q2","strtotime":1620844200,"product":"ELTROMBOPAG OLAMINE (RE-IMPORT VIDE SB.NO:6255582 DT:31.10.2020","address":"8-3-167\/D\/16, KALYAN NAGAR - I,VENGAL RAO NAGAR","city":"HYDERABAD, A.P.","supplier":"NOVUGEN","supplierCountry":"INDIA","foreign_port":"KUALA LUMPUR - INT\\'L","customer":"MSN LABORATORIES","customerCountry":"INDIA","quantity":"4.60","actualQuantity":"4.6","unit":"KGS","unitRateFc":"10000","totalValueFC":"48294.9","currency":"USD","unitRateINR":"769036.1","date":"13-May-2021","totalValueINR":"3537566.18","totalValueInUsd":"48294.9","indian_port":"HYDERABAD AIR","hs_no":"29163110","bill_no":"3933356","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"KUALA LUMPUR - INT\\'L","supplierAddress":"","customerAddress":"8-3-167\/D\/16, KALYAN NAGAR - I,VENGAL RAO NAGAR"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1654281000,"product":"ELTROMBOPAG OLAMINE MICRONIZED (BATCH NO.EPMA2310) (ELTROMBOPAG OLAMINE MICRONIZED) (FOR R&D PURPOSE ONLY)","address":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:","city":"MUMBAI","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"NA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"12000","totalValueFC":"6037.3","currency":"USD","unitRateINR":"942000","date":"04-Jun-2022","totalValueINR":"471000","totalValueInUsd":"6037.3","indian_port":"BOMBAY AIR","hs_no":"29147990","bill_no":"8972149","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1655749800,"product":"ELTROMBOPAG OLAMINE MICRONIZED (BATCH NO. EPMA2311)","address":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:","city":"MUMBAI","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"NA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"9200","totalValueFC":"9310.2","currency":"USD","unitRateINR":"726340","date":"21-Jun-2022","totalValueINR":"726340","totalValueInUsd":"9310.2","indian_port":"BOMBAY AIR","hs_no":"29147990","bill_no":"9217061","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1660242600,"product":"ELTROMBOPAG OLAMINE MICRONIZED (BATCH NO.EPMX1301) (ELTROMBOPAG OLAMINE MICRONIZED) (FOR R&D PURPOSE ONLY)","address":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:","city":"MUMBAI","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"NA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"9200","totalValueFC":"4639.5","currency":"USD","unitRateINR":"738300","date":"12-Aug-2022","totalValueINR":"369150","totalValueInUsd":"4639.5","indian_port":"BOMBAY AIR","hs_no":"29147990","bill_no":"9976786","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1672684200,"product":"ELTROMBOPAG OLAMINE MICRONIZED (BATCH NO.EPMA2314) (ELTROMBOPAG OLAMINE MICRONIZED) (FOR R&D PURPOSE ONLY)","address":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:","city":"MUMBAI","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"NA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.24","actualQuantity":"0.24","unit":"KGS","unitRateFc":"9200","totalValueFC":"2256.4","currency":"USD","unitRateINR":"768660","date":"03-Jan-2023","totalValueINR":"184478.4","totalValueInUsd":"2256.4","indian_port":"BOMBAY AIR","hs_no":"29147990","bill_no":"4014272","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1678905000,"product":"ELTROMBOPAG OLAMINE MICRONIZED (BATCH NO.EPMA3301) (ELTROMBOPAG OLAMINE MICRONIZED)","address":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:","city":"MUMBAI","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"NA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"9200","totalValueFC":"934","currency":"USD","unitRateINR":"768200","date":"16-Mar-2023","totalValueINR":"76820","totalValueInUsd":"934","indian_port":"BOMBAY AIR","hs_no":"29147990","bill_no":"5072987","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1683829800,"product":"ELTROMBOPAG OLAMINE MICRONIZED BATCH NO EPMA3303 ELTROMBOPAG OLAMINE MICRONIZED","address":"B,2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD","city":"MUMBAI","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"MADRID","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"9200","totalValueFC":"18470.6","currency":"USD","unitRateINR":"759920","date":"12-May-2023","totalValueINR":"1519840","totalValueInUsd":"18470.6","indian_port":"BOMBAY AIR","hs_no":"29147990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"Spain","selfForZScoreResived":"Micronized","supplierPort":"MADRID","supplierAddress":"","customerAddress":"B,2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1689705000,"product":"ELTROMBOPAG OLAMINE MICRONIZED (BATCH NO.EPMA3304) (ELTROMBOPAG OLAMINE MICRONIZED) (FOR R&D PURPOSE ONLY)","address":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:","city":"MUMBAI","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"NA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.25","actualQuantity":"0.25","unit":"KGS","unitRateFc":"9200","totalValueFC":"2329.7","currency":"USD","unitRateINR":"765900.2","date":"19-Jul-2023","totalValueINR":"191475.046","totalValueInUsd":"2329.7","indian_port":"BOMBAY AIR","hs_no":"29147990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1701369000,"product":"ELTROMBOPAG OLAMINE","address":"SECOND FLOOR, BLOCK-III,MY HOME HUB","city":"HYDERABAD, AP","supplier":"UNIPHARM LTD","supplierCountry":"INDIA","foreign_port":"TEL AVIV YAFO","customer":"GRANULES INDIA LIMITED","customerCountry":"INDIA","quantity":"11.50","actualQuantity":"11.5","unit":"KGS","unitRateFc":"6100","totalValueFC":"70872.1","currency":"USD","unitRateINR":"513010","date":"01-Dec-2023","totalValueINR":"5899615","totalValueInUsd":"70872.1","indian_port":"Hyderabad Air","hs_no":"29141990","bill_no":"9027545","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"TEL AVIV YAFO","supplierAddress":"1, SHEVET SHIMON STREET REG NO.510457666 TEL AVIVSDNF Israel","customerAddress":"SECOND FLOOR, BLOCK-III,MY HOME HUB"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1704738600,"product":"ELTROMBOPAG OLAMINE","address":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ","city":"AMRITSAR,PUNJAB","supplier":"M\/S. QUANZHOU FORTUNE TRADE CO. LTD.","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"KWALITY PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"2800","totalValueFC":"5676.7","currency":"USD","unitRateINR":"235900","date":"09-Jan-2024","totalValueINR":"471800","totalValueInUsd":"5676.7","indian_port":"Delhi Air","hs_no":"29339990","bill_no":"9583864","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"ADD:ROOM2603, RONG TAI\\'AN BUILDINGNO.139 JINHUAI STREET,FENGZE ROAD,FENGZE DISTRICT QUANZHOU CITY FUJIA CHINA","customerAddress":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730831400,"product":"7MP1042 4001328 ELTROMBOPAG OLAMINE (MICRONIZED)","address":"21-22, KALPATARU SQUARE, KONDIVITA","city":"ANDHERI (E), MUMBAI,MAHARASHTRA","supplier":"PLUSCHEM","supplierCountry":"CROATIA","foreign_port":"ZAGREB","customer":"TEVA PHARMACEUTICAL INDUSTRIES","customerCountry":"INDIA","quantity":"17.00","actualQuantity":"17","unit":"KGS","unitRateFc":"10000","totalValueFC":"205358.1","currency":"USD","unitRateINR":"1019400","date":"06-Nov-2024","totalValueINR":"17329800","totalValueInUsd":"205358.1","indian_port":"Bombay Air","hs_no":"29331999","bill_no":"6533523","productDescription":"API","marketType":"REGULATED MARKET","country":"CROATIA","selfForZScoreResived":"Micronized","supplierPort":"ZAGREB","supplierAddress":"BRANCH TEVA PHARMACEUTICALS INTL SC HLUESSELSTRASSE 12 JONA 8645, SDNF Switzerland","customerAddress":"21-22, KALPATARU SQUARE, KONDIVITA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730831400,"product":"7MP1042 4001328 ELTROMBOPAG OLAMINE (MICRONIZED)","address":"21-22, KALPATARU SQUARE, KONDIVITA","city":"ANDHERI (E), MUMBAI,MAHARASHTRA","supplier":"PLUSCHEM","supplierCountry":"CROATIA","foreign_port":"ZAGREB","customer":"TEVA PHARMACEUTICAL INDUSTRIES","customerCountry":"INDIA","quantity":"19.10","actualQuantity":"19.1","unit":"KGS","unitRateFc":"10000","totalValueFC":"230725.9","currency":"USD","unitRateINR":"1019400","date":"06-Nov-2024","totalValueINR":"19470540","totalValueInUsd":"230725.9","indian_port":"Bombay Air","hs_no":"29331999","bill_no":"6533523","productDescription":"API","marketType":"REGULATED MARKET","country":"CROATIA","selfForZScoreResived":"Micronized","supplierPort":"ZAGREB","supplierAddress":"BRANCH TEVA PHARMACEUTICALS INTL SC HLUESSELSTRASSE 12 JONA 8645, SDNF Switzerland","customerAddress":"21-22, KALPATARU SQUARE, KONDIVITA"}]
    24-Feb-2021
    26-Mar-2025
    KGS
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    Average Price (USD/KGS)

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    Quantity (KGS) & Unit rate (USD/KGS) over time

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    API Imports and Exports

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    INTERMEDIATE SUPPLIERS

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    01

    Ami Organics Private Limited

    India
    Arvo
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    Ami Organics Private Limited

    India
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    2-BROMO-6-NITROPHENOL

    CAS Number : 13073-25-1

    End Use API : Eltrombopag

    About The Company : Founded with a mission to transform strategic capital into specialty chemicals, Ami Group focuses on Agrochemicals, Cosmetics, and Polymers. Ami Organics Ltd. i...

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    02

    Ami Organics Private Limited

    India
    Arvo
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    Ami Organics Private Limited

    India
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    2-(3,4-DIMETHYLPHENYL)-5-METHYL-2,4-DIHYDRO- 3H-PY...

    CAS Number : 277299-70-4

    End Use API : Eltrombopag

    About The Company : Founded with a mission to transform strategic capital into specialty chemicals, Ami Group focuses on Agrochemicals, Cosmetics, and Polymers. Ami Organics Ltd. i...

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    03

    Aventus Labs

    India
    Arvo
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    Aventus Labs

    India
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    2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyr...

    CAS Number : 18048-64-1

    End Use API : Eltrombopag

    About The Company : Aventus Labs is a forward-thinking pharmaceutical company committed to developing and delivering high-quality, effective healthcare solutions. With a focus on r...

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    04

    Aventus Labs

    India
    Arvo
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    Aventus Labs

    India
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    3-Amino-2-hydroxybiphenyl-3-carboxylic acid

    CAS Number : 376592-93-7

    End Use API : Eltrombopag

    About The Company : Aventus Labs is a forward-thinking pharmaceutical company committed to developing and delivering high-quality, effective healthcare solutions. With a focus on r...

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    05

    Guangdong Raffles PharmaTech Co Ltd

    China
    Arvo
    Not Confirmed
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    Guangdong Raffles PharmaTech Co Ltd

    China
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    3'-amino-2'-hydroxybiphenyl-3-carboxylic acid

    CAS Number : 376592-93-7

    End Use API : Eltrombopag

    About The Company : Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceu...

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    06

    Guangdong Raffles PharmaTech Co Ltd

    China
    Arvo
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    Guangdong Raffles PharmaTech Co Ltd

    China
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    2'-hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic a...

    CAS Number : 376591-95-6

    End Use API : Eltrombopag

    About The Company : Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceu...

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    07

    Guangdong Raffles PharmaTech Co Ltd

    China
    Arvo
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    Guangdong Raffles PharmaTech Co Ltd

    China
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    3'-amino-2'-hydroxybiphenyl-3-carboxylic acid HCl

    CAS Number : 376591-97-8

    End Use API : Eltrombopag

    About The Company : Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceu...

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    08

    Guangdong Raffles PharmaTech Co Ltd

    China
    Arvo
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    Guangdong Raffles PharmaTech Co Ltd

    China
    Arvo
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    5'-chloro-2'-hydroxy-3'-nitro-[1,1'-Biphenyl]-3-ca...

    CAS Number : 376592-58-4

    End Use API : Eltrombopag

    About The Company : Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceu...

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    09

    Guangdong Raffles PharmaTech Co Ltd

    China
    Arvo
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    Guangdong Raffles PharmaTech Co Ltd

    China
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    5'-chloro-2'-hydroxy-[1, 1'-Bipheny l]-3-carboxyli...

    CAS Number : 376592-57-3

    End Use API : Eltrombopag

    About The Company : Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceu...

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    10

    Guangdong Raffles PharmaTech Co Ltd

    China
    Arvo
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    Guangdong Raffles PharmaTech Co Ltd

    China
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    3-methyl-1-(3,4-dimethylphenyl)-2-pyrazolin-5-one ...

    CAS Number : 18048-64-1-277299-70-4

    End Use API : Eltrombopag

    About The Company : Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceu...

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    FDA Orange Book

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    01

    AMNEAL EU LTD

    Germany
    AMWC Asia-TDAC
    Not Confirmed
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    AMNEAL EU LTD

    Germany
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    AMWC Asia-TDAC
    Not Confirmed
    • fda
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    RLD :

    TE Code :

    ELTROMBOPAG

    Brand Name : ELTROMBOPAG

    Dosage Form : TABLET; ORAL

    Dosage Strength : 50MG

    Approval Date :

    Application Number : 212884

    RX/OTC/DISCN :

    RLD :

    TE Code :

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    02

    AMNEAL EU LTD

    Germany
    AMWC Asia-TDAC
    Not Confirmed
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    AMNEAL EU LTD

    Germany
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    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
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    RLD :

    TE Code :

    ELTROMBOPAG

    Brand Name : ELTROMBOPAG

    Dosage Form : TABLET; ORAL

    Dosage Strength : 75MG

    Approval Date :

    Application Number : 212884

    RX/OTC/DISCN :

    RLD :

    TE Code :

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    03

    ANNORA PHARMA

    India
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    ANNORA PHARMA

    India
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    AMWC Asia-TDAC
    Not Confirmed
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    RLD : No

    TE Code : AB

    ELTROMBOPAG OLAMINE

    Brand Name : ELTROMBOPAG OLAMINE

    Dosage Form : FOR SUSPENSION;ORAL

    Dosage Strength : EQ 12.5MG ACID/PACKET

    Approval Date : 2024-04-18

    Application Number : 216620

    RX/OTC/DISCN : RX

    RLD : No

    TE Code : AB

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    04

    ANNORA PHARMA

    India
    AMWC Asia-TDAC
    Not Confirmed
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    ANNORA PHARMA

    India
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    AMWC Asia-TDAC
    Not Confirmed
    • fda
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    RLD : No

    TE Code : AB

    ELTROMBOPAG OLAMINE

    Brand Name : ELTROMBOPAG OLAMINE

    Dosage Form : FOR SUSPENSION;ORAL

    Dosage Strength : EQ 25MG ACID/PACKET

    Approval Date : 2024-04-18

    Application Number : 216620

    RX/OTC/DISCN : RX

    RLD : No

    TE Code : AB

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    05

    TEVA PHARMS INC

    Israel
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    TEVA PHARMS INC

    Israel
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    RLD : Yes

    TE Code :

    ELTROMBOPAG CHOLINE

    Brand Name : ALVAIZ

    Dosage Form : TABLET;ORAL

    Dosage Strength : EQ 9MG BASE

    Approval Date : 2023-11-29

    Application Number : 216774

    RX/OTC/DISCN : RX

    RLD : Yes

    TE Code :

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    06

    HETERO LABS LTD V

    India
    AMWC Asia-TDAC
    Not Confirmed
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    HETERO LABS LTD V

    India
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    AMWC Asia-TDAC
    Not Confirmed
    • fda
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    RLD : No

    TE Code : AB

    ELTROMBOPAG OLAMINE

    Brand Name : ELTROMBOPAG OLAMINE

    Dosage Form : TABLET;ORAL

    Dosage Strength : EQ 12.5MG ACID

    Approval Date : 2025-01-17

    Application Number : 206788

    RX/OTC/DISCN : RX

    RLD : No

    TE Code : AB

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    07

    HETERO LABS LTD V

    India
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    HETERO LABS LTD V

    India
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
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    RLD : No

    TE Code : AB

    ELTROMBOPAG OLAMINE

    Brand Name : ELTROMBOPAG OLAMINE

    Dosage Form : TABLET;ORAL

    Dosage Strength : EQ 25MG ACID

    Approval Date : 2025-01-17

    Application Number : 206788

    RX/OTC/DISCN : RX

    RLD : No

    TE Code : AB

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    08

    NOVARTIS

    Switzerland
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    NOVARTIS

    Switzerland
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
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    RLD : Yes

    TE Code : AB

    ELTROMBOPAG OLAMINE

    Brand Name : PROMACTA

    Dosage Form : TABLET;ORAL

    Dosage Strength : EQ 50MG ACID

    Approval Date : 2008-11-20

    Application Number : 22291

    RX/OTC/DISCN : RX

    RLD : Yes

    TE Code : AB

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    09

    NOVARTIS

    Switzerland
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    NOVARTIS

    Switzerland
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    Digital Content Digital Content

    RLD : Yes

    TE Code : AB

    ELTROMBOPAG OLAMINE

    Brand Name : PROMACTA

    Dosage Form : TABLET;ORAL

    Dosage Strength : EQ 75MG ACID

    Approval Date : 2009-09-08

    Application Number : 22291

    RX/OTC/DISCN : RX

    RLD : Yes

    TE Code : AB

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    10

    NOVARTIS

    Switzerland
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    NOVARTIS

    Switzerland
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
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    RLD : Yes

    TE Code : AB

    ELTROMBOPAG OLAMINE

    Brand Name : PROMACTA

    Dosage Form : TABLET;ORAL

    Dosage Strength : EQ 12.5MG ACID

    Approval Date : 2011-10-20

    Application Number : 22291

    RX/OTC/DISCN : RX

    RLD : Yes

    TE Code : AB

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    Europe

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    01

    ALFRED E TIEFENBACHER GmbH & Co KG

    Germany
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothWe are the TIEFENBACHER GROUP, Health Pioneers since 1963.

    Contact Supplier Contact Supplier
    Flag Germany
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    Regulatory Info : EU Dossier Readiness-Q2 2019

    Registration Country : Germany

    Eltrombopag

    Brand Name :

    Dosage Form : Film Coated Tablet

    Dosage Strength : 12.5MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info : EU Dossier Readiness-Q2 2019

    Registration Country : Germany

    Tiefenbacher Compnay Banner

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    02

    ALFRED E TIEFENBACHER GmbH & Co KG

    Germany
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothWe are the TIEFENBACHER GROUP, Health Pioneers since 1963.

    Contact Supplier Contact Supplier
    Flag Germany
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : EU Dossier Readiness-Q2 2019

    Registration Country : Germany

    Eltrombopag

    Brand Name :

    Dosage Form : Film Coated Tablet

    Dosage Strength : 25MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info : EU Dossier Readiness-Q2 2019

    Registration Country : Germany

    Tiefenbacher Compnay Banner

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    03

    ALFRED E TIEFENBACHER GmbH & Co KG

    Germany
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothWe are the TIEFENBACHER GROUP, Health Pioneers since 1963.

    Contact Supplier Contact Supplier
    Flag Germany
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : EU Dossier Readiness-Q2 2019

    Registration Country : Germany

    Eltrombopag

    Brand Name :

    Dosage Form : Film Coated Tablet

    Dosage Strength : 50MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info : EU Dossier Readiness-Q2 2019

    Registration Country : Germany

    Tiefenbacher Compnay Banner

    Portfolio PDF

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    Digital Content

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    04

    ALFRED E TIEFENBACHER GmbH & Co KG

    Germany
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothWe are the TIEFENBACHER GROUP, Health Pioneers since 1963.

    Contact Supplier Contact Supplier
    Flag Germany
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : EU Dossier Readiness-Q2 2019

    Registration Country : Germany

    Eltrombopag

    Brand Name :

    Dosage Form : Film Coated Tablet

    Dosage Strength : 75MG

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info : EU Dossier Readiness-Q2 2019

    Registration Country : Germany

    Tiefenbacher Compnay Banner

    Portfolio PDF

    Product Web Link

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    Digital Content

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    05

    Novartis Pharma Schweiz AG

    Switzerland
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    Novartis Pharma Schweiz AG

    Switzerland
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Switzerland

    Eltrombopagum

    Brand Name : Revolade

    Dosage Form : Filmtable

    Dosage Strength : 25mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    06

    Novartis Pharma Schweiz AG

    Switzerland
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    Novartis Pharma Schweiz AG

    Switzerland
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Switzerland

    Eltrombopagum

    Brand Name : Revolade

    Dosage Form : Filmtable

    Dosage Strength : 25mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    07

    Novartis Pharma Schweiz AG

    Switzerland
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    Novartis Pharma Schweiz AG

    Switzerland
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Switzerland

    Eltrombopagum

    Brand Name : Revolade

    Dosage Form : Filmtable

    Dosage Strength : 50mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    08

    Novartis Pharma Schweiz AG

    Switzerland
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    Novartis Pharma Schweiz AG

    Switzerland
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Switzerland

    Eltrombopagum

    Brand Name : Revolade

    Dosage Form : Filmtable

    Dosage Strength : 50mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    09

    Novartis Pharma Schweiz AG

    Switzerland
    AMWC Asia-TDAC
    Not Confirmed
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    Novartis Pharma Schweiz AG

    Switzerland
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Switzerland

    Eltrombopagum

    Brand Name : Revolade

    Dosage Form : Filmtabl

    Dosage Strength : 75mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    10

    Novartis Pharma Schweiz AG

    Switzerland
    AMWC Asia-TDAC
    Not Confirmed
    arrow

    Novartis Pharma Schweiz AG

    Switzerland
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Regulatory Info :

    Registration Country : Switzerland

    Eltrombopagum

    Brand Name : Revolade

    Dosage Form : Filmtable

    Dosage Strength : 12.5mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    DRUG PRODUCT COMPOSITIONS

    Do you need Business Intel? Ask us

    DOSAGE - TABLET;ORAL - EQ 100MG ACID **Federa...DOSAGE - TABLET;ORAL - EQ 100MG ACID **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 22291

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    DOSAGE - TABLET;ORAL - EQ 12.5MG ACID

    USFDA APPLICATION NUMBER - 22291

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    DOSAGE - TABLET;ORAL - EQ 25MG ACID

    USFDA APPLICATION NUMBER - 22291

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    DOSAGE - TABLET;ORAL - EQ 50MG ACID

    USFDA APPLICATION NUMBER - 22291

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    DOSAGE - TABLET;ORAL - EQ 75MG ACID

    USFDA APPLICATION NUMBER - 22291

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    Related Excipient Companies

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    Excipients by Applications

    Click here to find the perfect excipient manufacturers by their capabilities

    Coating Systems & Additives

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    01

    SPI Pharma

    U.S.A
    arrow
    CPhI North America
    Attending
    • fda
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    • WHO-GMP

    Virtual BoothSPI Pharma has been solving formulation challenges using superior functional materials.

    Brand Name : Mannogem Powder

    Application : Fillers, Diluents & Binders, Granulation, Solubilizers

    Excipient Details : Mannogem (mannitol powder) is an excellent excipient for use in wet granulation, lyophilization & improves solubility of poorly soluble APIs.

    Pharmacopoeia Ref : NA

    Technical Specs : NA

    Ingredient(s) : Mannitol

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    Mannogem Powder

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    02

    Nanjing Well Pharmaceutical

    China
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

    Brand Name : Polysorbate 80

    Application : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

    Excipient Details : Polysorbate 80 is used as a plasticizer, solubilizer, emulsifier, surfactant, and suspension stabilizer. It is also used in parenteral products.

    Pharmacopoeia Ref : ChP/USP/EP/JP

    Technical Specs : NA

    Ingredient(s) : Polysorbate 80

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    Polysorbate 80

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    03

    Nanjing Bold Chemical

    China
    AMWC Asia-TDAC
    Not Confirmed
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    04

    The Dow Chemical Company

    U.S.A
    AMWC Asia-TDAC
    Not Confirmed
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    05

    BASF

    Germany
    AMWC Asia-TDAC
    Not Confirmed
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    06

    Seppic

    France
    AMWC Asia-TDAC
    Not Confirmed
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    07

    Actylis

    U.S.A
    AMWC Asia-TDAC
    Not Confirmed
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    08

    Microlex e.U

    Austria
    AMWC Asia-TDAC
    Not Confirmed
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    09

    Actylis

    U.S.A
    AMWC Asia-TDAC
    Not Confirmed
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    10

    Gangwal Chemicals

    India
    AMWC Asia-TDAC
    Not Confirmed
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    Granulation

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    01

    Rochem International Inc

    U.S.A
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    CPhI WW Frankfurt
    Booth #12.0F117
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothRochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

    Dosage Form : Tablet

    Grade : Oral

    Category : Fillers, Diluents & Binders, Taste Masking

    Brand Name : Mannitol

    Application : Fillers, Diluents & Binders, Taste Masking

    Excipient Details : Mannitol is used as a filler, bulking agent and taste masking agent in ODT formulations such as tablets.

    Pharmacopoeia Ref : NA

    Technical Specs : NA

    Ingredient(s) : Mannitol

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    Mannitol

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    02

    Faran Shimi Pharmaceutical

    Iran
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothFaran Shimi: Leading producer of high-quality APIs & alkaloid opiates, serving major pharmaceutical companies across the Middle East.

    Dosage Form : Tablet

    Grade : Oral

    Category : Co-Processed Excipients

    Brand Name : Mannitol

    Application : Co-Processed Excipients

    Excipient Details : Mannitol is a co-processed excipient with superior compactibility, lower disintegration time, and hygroscopicity.

    Pharmacopoeia Ref : NA

    Technical Specs : NA

    Ingredient(s) : Mannitol

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    Mannitol

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    03

    Nanjing Well Pharmaceutical

    China
    arrow
    AMWC Asia-TDAC
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

    Brand Name : Polysorbate 80

    Application : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

    Excipient Details : Polysorbate 80 is used as a plasticizer, solubilizer, emulsifier, surfactant, and suspension stabilizer. It is also used in parenteral products.

    Pharmacopoeia Ref : ChP/USP/EP/JP

    Technical Specs : NA

    Ingredient(s) : Polysorbate 80

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    Polysorbate 80

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    04

    Pfanstiehl

    U.S.A
    arrow
    AMWC Asia-TDAC
    Not Confirmed
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    Virtual BoothPfanstiehl, a global leader in the manufacture of cGMP high purity, low endotoxin, low metals (HPLE-LM)TM injectable grade excipients.

    Brand Name : D-Mannitol

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    Excipient Details : D-mannitol protects proteins from denaturation & degradation. It is also used as a stabilizer in liquid formulations & as a bulking agent in tablets.

    Pharmacopoeia Ref : USP, NF, EP, JP, ChP

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    Nanjing Well Pharmaceutical

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    Brand Name : Polyethylene Glycol 400

    Application : Fillers, Diluents & Binders, Film Formers & Plasticizers, Parenteral, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

    Excipient Details : PEG 400 is used as a suspending agent, stabilizer, plasticizer and filler in OSDs, liquids & semi-solids and as a solvent for parenteral formulations.

    Pharmacopoeia Ref : ChP/USP/EP

    Technical Specs : NA

    Ingredient(s) : Polyethylene Glycol 400

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    Shijiazhuang Huaxu Pharmaceutical

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    AMWC Asia-TDAC
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    India
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    U.S.A
    AMWC Asia-TDAC
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    Brand Name : XANTURAL® 11000

    Application : Rheology Modifiers, Thickeners and Stabilizers, Topical

    Excipient Details : Xantural 11000 is used as a stabilizer and rheology modifier in oral dosage forms such as syrups, suspensions & solutions & in topical formulations.

    Pharmacopoeia Ref : JP, EP, USP/NF

    Technical Specs : N/A

    Ingredient(s) : Xanthan Gum

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    Brand Name : Polysorbate 80

    Application : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

    Excipient Details : Polysorbate 80 is used as a plasticizer, solubilizer, emulsifier, surfactant, and suspension stabilizer. It is also used in parenteral products.

    Pharmacopoeia Ref : ChP/USP/EP/JP

    Technical Specs : NA

    Ingredient(s) : Polysorbate 80

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    Virtual BoothDKSH is your trusted partner for companies looking to grow their business in Asia & beyond.

    Brand Name : XANTURAL® 180

    Application : Rheology Modifiers, Thickeners and Stabilizers, Topical

    Excipient Details : Xantural 180 is used as a rheology modifier & stabilizer in oral dosage forms such as solutions, suspensions, and syrups & in topical formulations.

    Pharmacopoeia Ref : JP, EP, USP/NF

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    Nanjing Well Pharmaceutical

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    Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

    Brand Name : Polyethylene Glycol 400

    Application : Fillers, Diluents & Binders, Film Formers & Plasticizers, Parenteral, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

    Excipient Details : PEG 400 is used as a suspending agent, stabilizer, plasticizer and filler in OSDs, liquids & semi-solids and as a solvent for parenteral formulations.

    Pharmacopoeia Ref : ChP/USP/EP

    Technical Specs : NA

    Ingredient(s) : Polyethylene Glycol 400

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    Nanjing Bold Chemical

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    AMWC Asia-TDAC
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    Clariant

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    Finar

    India
    AMWC Asia-TDAC
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    AMWC Asia-TDAC
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    U.S.A
    AMWC Asia-TDAC
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    AMWC Asia-TDAC
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    01

    Brand Name : Promacta

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    Company :

    Eltrombopag Olamine

    Drug Cost (USD) : 454,825,188

    Year : 2022

    Prescribers : 5150

    Prescriptions : 35692

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    Brand Name : Promacta

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    Company :

    Eltrombopag Olamine

    Drug Cost (USD) : 389,486,269

    Year : 2021

    Prescribers : 4960

    Prescriptions : 32978

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    Brand Name : Promacta

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    Company :

    Eltrombopag Olamine

    Drug Cost (USD) : 341,789,027

    Year : 2020

    Prescribers : 4616

    Prescriptions : 31379

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    Brand Name : Promacta

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    Company :

    Eltrombopag Olamine

    Drug Cost (USD) : 304,352,153

    Year : 2019

    Prescribers : 4977

    Prescriptions : 31057

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    Brand Name : Promacta

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    Company :

    Eltrombopag Olamine

    Drug Cost (USD) : 254,107,970

    Year : 2018

    Prescribers : 4759

    Prescriptions : 29025

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    Brand Name : Promacta

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    Company :

    Eltrombopag Olamine

    Drug Cost (USD) : 189,364,721

    Year : 2017

    Prescribers : 3957

    Prescriptions : 24054

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    07

    Brand Name : Promacta

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    Company :

    Eltrombopag Olamine

    Drug Cost (USD) : 76,444,781

    Year : 2016

    Prescribers : 3124

    Prescriptions : 10294

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    Brand Name : Promacta

    Country
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    Company :

    Eltrombopag Olamine

    Drug Cost (USD) : 0

    Year : 2015

    Prescribers : 2525

    Prescriptions : 0

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    Brand Name : PROMACTA

    Country
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    AAPS National Biotech
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    Company :

    ELTROMBOPAG OLAMINE

    Drug Cost (USD) : 56,535,928

    Year : 2014

    Prescribers : 1958

    Prescriptions : 10635

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    Brand Name : Promacta/Revolade

    Eltrombopag

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    AAPS National Biotech
    Not Confirmed

    Brand Name : Promacta/Revolade

    Switzerland
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    AAPS National Biotech
    Not Confirmed

    Novartis

    Eltrombopag

    Main Therapeutic Indication : Oncology

    Currency : USD

    2020 Revenue in Millions : 1,738

    2019 Revenue in Millions : 1,416

    Growth (%) : 23

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    Brand Name : Promacta/Revolade

    Eltrombopag Olamine

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    AAPS National Biotech
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    Brand Name : Promacta/Revolade

    Switzerland
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    AAPS National Biotech
    Not Confirmed

    Novartis

    Eltrombopag Olamine

    Main Therapeutic Indication : Oncology

    Currency : USD

    2020 Revenue in Millions : 1,738

    2019 Revenue in Millions : 1,416

    Growth (%) : 23

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    03

    Brand Name : Promacta/Revolade

    Eltrombopag

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    AAPS National Biotech
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    Brand Name : Promacta/Revolade

    Switzerland
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    AAPS National Biotech
    Not Confirmed

    Novartis

    Eltrombopag

    Main Therapeutic Indication : Oncology

    Currency : USD

    2021 Revenue in Millions : 2,016

    2020 Revenue in Millions : 1,738

    Growth (%) : 16

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    04

    Brand Name : Promacta/Revolade

    Eltrombopag Olamine

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    AAPS National Biotech
    Not Confirmed

    Brand Name : Promacta/Revolade

    Switzerland
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    AAPS National Biotech
    Not Confirmed

    Novartis

    Eltrombopag Olamine

    Main Therapeutic Indication : Oncology

    Currency : USD

    2021 Revenue in Millions : 2,016

    2020 Revenue in Millions : 1,738

    Growth (%) : 16

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    05

    Brand Name : Promacta/Revolade

    Eltrombopag Olamine

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    AAPS National Biotech
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    Brand Name : Promacta/Revolade

    Switzerland
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    AAPS National Biotech
    Not Confirmed

    Novartis

    Eltrombopag Olamine

    Main Therapeutic Indication : Hematology

    Currency : USD

    2022 Revenue in Millions : 2,088

    2021 Revenue in Millions : 2,016

    Growth (%) : 4

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    06

    Brand Name : Promacta/Revolade

    Eltrombopag

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    AAPS National Biotech
    Not Confirmed

    Brand Name : Promacta/Revolade

    Switzerland
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    AAPS National Biotech
    Not Confirmed

    Novartis

    Eltrombopag

    Main Therapeutic Indication : Hematology

    Currency : USD

    2022 Revenue in Millions : 2,088

    2021 Revenue in Millions : 2,016

    Growth (%) : 4

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    Brand Name : Promacta/Revolade

    Eltrombopag Olamine

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    AAPS National Biotech
    Not Confirmed

    Brand Name : Promacta/Revolade

    Switzerland
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    AAPS National Biotech
    Not Confirmed

    Novartis

    Eltrombopag Olamine

    Main Therapeutic Indication : Oncology

    Currency : USD

    2023 Revenue in Millions : 2,269

    2022 Revenue in Millions : 2,088

    Growth (%) : 9

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    Brand Name : Promacta/Revolade

    Eltrombopag

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    AAPS National Biotech
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    Brand Name : Promacta/Revolade

    Switzerland
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    AAPS National Biotech
    Not Confirmed

    Novartis

    Eltrombopag

    Main Therapeutic Indication : Oncology

    Currency : USD

    2023 Revenue in Millions : 2,269

    2022 Revenue in Millions : 2,088

    Growth (%) : 9

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    Brand Name : Promacta

    EltroMbopag diethanolaMine salt

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    Brand Name : Promacta

    United Kingdom
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    GlaxoSmithKline

    EltroMbopag diethanolaMine salt

    Main Therapeutic Indication : Oncology

    Currency : USD

    2014 Revenue in Millions : 24.20%

    2013 Revenue in Millions :

    Growth (%) :

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    Brand Name : Revolade/Promacta

    EltroMbopag diethanolaMine salt

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    AAPS National Biotech
    Not Confirmed

    Brand Name : Revolade/Promacta

    Switzerland
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    AAPS National Biotech
    Not Confirmed

    Novartis

    EltroMbopag diethanolaMine salt

    Main Therapeutic Indication : Oncology

    Currency : USD

    2015 Revenue in Millions : 0

    2014 Revenue in Millions : 402

    Growth (%) : New Launch

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    VietNam.png
    Oral grade Eltrombopag Olamine API needed in Vietnam [ENA20223]
    A company that focuses on manufacturing and distribution of pharmaceutical products, medicinal herbs and medical equipment is looking for suppliers of Oral grade Eltrombopag Olamine API for commercial purposes. The required quantity is 250 g, 500 g, 1 kg, 2 kg & 5 kg. The suppliers must support this enquiry with DMF, GMP & CoA.
    09 Aug 2024

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    09 Aug 2024

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    09 Aug 2024

    Oman.png
    USP/ Ph. Eur. Grade Eltrombopag Olamine API needed in Oman [ENA19636]
    A company that focuses on manufacturing and development of various finished formulation including oral solid, oral liquid & topical dosage forms is looking for suppliers of USP/ Ph. Eur. Grade Eltrombopag Olamine API for both development & commercial purposes. The required quantity 73 g for first year, 378 g for second year, 1.2 kg for third year, 1.5 kg for fourth year, 1.8 kg for fifth year, 2.2 kg for sixth year, 2.6 kg for seventh year & 2 kg for eighth year. The suppliers must support this enquiry with USDMF/ CEP, GMP & CoA.
    04 Jun 2024

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    04 Jun 2024

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    Reply Comment (8)

    04 Jun 2024

    india-flag.png
    Eltrombopag Olamine API needed in India [ENA19603]
    A CRO that provides formulation and analytical development services for OSDs, parenteral and liquid orals is looking for suppliers of Eltrombopag Olamine API. The required quantity is 1 kg for development and 30 kg for commercial purposes. The suppliers must support this enquiry with ODMF & CoA.
    29 May 2024

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    29 May 2024

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    Reply Comment (2)

    29 May 2024

    india-flag.png
    Various APIs needed in India [ENA15174]
    A company that focuses on the manufacturing of pharmaceuticals is looking for suppliers of Various APIs. The suppliers must support this enquiry with CoA. 1. Asenapine API 2. Axitinib API 3. Fesoterodine Fumarate API 4. Eltrombopag Olamine API
    30 Sep 2022

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    30 Sep 2022

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    Reply Comment (4)

    30 Sep 2022

    Kazakhstan.png
    Various APIs needed in Kazakhstan [ENA14980]
    A company that deals in various pharmaceutical products is looking for suppliers of Various APIs for commercial purpose. The suppliers must support this enquiry with CoA. 1. Ramipril (MOQ) API 2. Irbesartan (1.5 MT/ annum) API 3. Telmisartan (1.3 MT/ annum) API 4. Sacubitril + Valsartan (1.5 MT/ annum) API 5. Eltrombopag Olamine (80 kg/ annum) API 6. Telmisartan Granules SD & DC (MOQ) API 7. Meglumine (MOQ) API
    09 Sep 2022

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    09 Sep 2022

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    Reply Comment (16)

    09 Sep 2022

    Canada.png
    Eltrombopag (20 kg/ annum) API needed in Canada [ENA14362]
    A CDMO that specializes in complex oral solid dose, liquids, semi-solids and nasal sprays for pharmaceutical Rx and OTC products is looking for suppliers of Eltrombopag (20 kg/ annum) API for commercial purpose. The suppliers must support this enquiry with USDMF.
    15 Jul 2022

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    15 Jul 2022

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    Reply Comment (7)

    15 Jul 2022

    Bangladesh.png
    Various APIs needed in Bangladesh [ENA13624]
    A company that deals in various pharmaceutical products is looking for suppliers of Various APIs for commercial purpose. The suppliers must support this enquiry with CoA. 1. Pilocarpine (5 kg) API 2. Eltrombopag (2 kg) API
    13 May 2022

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    13 May 2022

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    Reply Comment (3)

    13 May 2022

    Bangladesh.png
    Eltrombopag Olamine API needed in Bangladesh [ENA13597]
    A company that deals in various pharmaceutical products is looking for suppliers of Eltrombopag Olamine API for commercial purpose. The suppliers must support this enquiry with CoA.
    10 May 2022

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    10 May 2022

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    Reply Comment (10)

    10 May 2022

    Egypt.png
    Various APIs needed in Egypt [ENA10114]
    A company that deals in various pharmaceutical products including hard gelatin capsules, tablets and dietary supplements is looking for suppliers of Various APIs for commercial purposes. The required quantity is MOQ for each. The suppliers must support this enquiry with CoA and GMP. 1. Betamethasone Sodium Phosphate API 2. Sterile Cyanocobalamin API 3. Ondansetron HCl API 4. Olsalazine API 5. Folic Acid API 6. Sodium Bicarbonate API 7. Orotic Acid API 8. Ceftolozane Sulfate API 9. Etoricoxib API 10. Thiamine API 11. Ascorbic Acid API 12. Eucalyptus Oil API 13. Eltrombopag Olamine API 14. Nicotinamide API 15. Benfotiamine API 16. Pyridoxine HCl API
    03 Apr 2021

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    03 Apr 2021

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    03 Apr 2021

    VietNam.png
    Various APIs needed in Vietnam [ENA09884]
    One of the fastest growing organizations in the pharmaceutical industry is looking for suppliers of Various APIs for commercial manufacturing purposes. The suppliers must support this enquiry with GMP and DMF. 1. Apixaban (3 kg) API 2. Bupropion (25 kg) API 3. Canagliflozin (50 kg) API 4. Cyclobenzaprine HCl (10 kg) API 5. Eltrombopag Olamine (10 kg) API 6. Empagliflozin (10 kg) API 7. Lenalidomid (5 kg) API 8. Posaconazole (5 kg) API 9. Prasugrel (5 kg) API 10. Trazodone (20 kg) API
    06 Mar 2021

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    06 Mar 2021

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    06 Mar 2021

    Only 10 entries up to this point, click to access all click full view read-more
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    Patents & EXCLUSIVITIES

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    US Patents

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    01

    TEVA PHARMS INC

    ELTROMBOPAG CHOLINE

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    Arvo
    Not Confirmed

    TEVA PHARMS INC

    Israel
    arrow
    Arvo
    Not Confirmed

    Patent Expiration Date : 2038-11-05

    ELTROMBOPAG CHOLINE

    US Patent Number : 11072586

    Drug Substance Claim : Y

    Drug Product Claim : Y

    Application Number : 216774

    Patent Use Code : U-3937

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2038-11-05

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    02

    TEVA PHARMS INC

    ELTROMBOPAG CHOLINE

    arrow
    Arvo
    Not Confirmed

    TEVA PHARMS INC

    Israel
    arrow
    Arvo
    Not Confirmed

    Patent Expiration Date : 2038-11-05

    ELTROMBOPAG CHOLINE

    US Patent Number : 11072586

    Drug Substance Claim : Y

    Drug Product Claim : Y

    Application Number : 216774

    Patent Use Code : U-3937

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2038-11-05

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    03

    NOVARTIS

    ELTROMBOPAG OLAMINE

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    Arvo
    Not Confirmed

    NOVARTIS

    Switzerland
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    Arvo
    Not Confirmed

    Patent Expiration Date : 2025-07-13

    ELTROMBOPAG OLAMINE

    US Patent Number : 7547719

    Drug Substance Claim : Y

    Drug Product Claim : Y

    Application Number : 22291

    Patent Use Code : U-2452

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2025-07-13

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    04

    NOVARTIS

    ELTROMBOPAG OLAMINE

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    Arvo
    Not Confirmed

    NOVARTIS

    Switzerland
    arrow
    Arvo
    Not Confirmed

    Patent Expiration Date : 2028-02-01

    ELTROMBOPAG OLAMINE

    US Patent Number : 8052993*PED

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 22291

    Patent Use Code :

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2028-02-01

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    05

    NOVARTIS

    ELTROMBOPAG OLAMINE

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    Arvo
    Not Confirmed

    NOVARTIS

    Switzerland
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    Arvo
    Not Confirmed

    Patent Expiration Date : 2027-08-01

    ELTROMBOPAG OLAMINE

    US Patent Number : 8062665

    Drug Substance Claim :

    Drug Product Claim : Y

    Application Number : 22291

    Patent Use Code : U-1714

    Delist Requested :

    Patent Use Description : TREATMENT OF THROMBOCY...

    Patent Expiration Date : 2027-08-01

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    06

    NOVARTIS

    ELTROMBOPAG OLAMINE

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    Arvo
    Not Confirmed

    NOVARTIS

    Switzerland
    arrow
    Arvo
    Not Confirmed

    Patent Expiration Date : 2028-02-01

    ELTROMBOPAG OLAMINE

    US Patent Number : 8828430*PED

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 22291

    Patent Use Code :

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2028-02-01

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    Portfolio PDF

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    07

    NOVARTIS

    ELTROMBOPAG OLAMINE

    arrow
    Arvo
    Not Confirmed

    NOVARTIS

    Switzerland
    arrow
    Arvo
    Not Confirmed

    Patent Expiration Date : 2025-07-13

    ELTROMBOPAG OLAMINE

    US Patent Number : 7547719

    Drug Substance Claim : Y

    Drug Product Claim : Y

    Application Number : 207027

    Patent Use Code : U-1306

    Delist Requested :

    Patent Use Description : TREATMENT OF THROMBOCY...

    Patent Expiration Date : 2025-07-13

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    Portfolio PDF

    Product Web Link

    Virtual Booth

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    Corporate PDF

    08

    NOVARTIS

    ELTROMBOPAG OLAMINE

    arrow
    Arvo
    Not Confirmed

    NOVARTIS

    Switzerland
    arrow
    Arvo
    Not Confirmed

    Patent Expiration Date : 2025-07-13

    ELTROMBOPAG OLAMINE

    US Patent Number : 7547719

    Drug Substance Claim : Y

    Drug Product Claim : Y

    Application Number : 22291

    Patent Use Code : U-1575

    Delist Requested :

    Patent Use Description : PATIENTS WITH SEVERE A...

    Patent Expiration Date : 2025-07-13

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    Portfolio PDF

    Product Web Link

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    09

    NOVARTIS

    ELTROMBOPAG OLAMINE

    arrow
    Arvo
    Not Confirmed

    NOVARTIS

    Switzerland
    arrow
    Arvo
    Not Confirmed

    Patent Expiration Date : 2028-02-01

    ELTROMBOPAG OLAMINE

    US Patent Number : 8062665*PED

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 22291

    Patent Use Code :

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2028-02-01

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    10

    NOVARTIS

    ELTROMBOPAG OLAMINE

    arrow
    Arvo
    Not Confirmed

    NOVARTIS

    Switzerland
    arrow
    Arvo
    Not Confirmed

    Patent Expiration Date : 2027-08-01

    ELTROMBOPAG OLAMINE

    US Patent Number : 8052993

    Drug Substance Claim :

    Drug Product Claim : Y

    Application Number : 22291

    Patent Use Code : U-1714

    Delist Requested :

    Patent Use Description : TREATMENT OF THROMBOCY...

    Patent Expiration Date : 2027-08-01

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

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    ABOUT THIS PAGE

    Looking for 496775-62-3 / Eltrombopag API manufacturers, exporters & distributors?

    Eltrombopag manufacturers, exporters & distributors 1

    33

    PharmaCompass offers a list of Eltrombopag API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Eltrombopag manufacturer or Eltrombopag supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Eltrombopag manufacturer or Eltrombopag supplier.

    PharmaCompass also assists you with knowing the Eltrombopag API Price utilized in the formulation of products. Eltrombopag API Price is not always fixed or binding as the Eltrombopag Price is obtained through a variety of data sources. The Eltrombopag Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Eltrombopag

    Synonyms

    496775-62-3, Revolade, Promacta, Eltrombopag (olamine), Unii-4u07f515lg, Sb-497115-gr

    Cas Number

    496775-62-3

    Unique Ingredient Identifier (UNII)

    4U07F515LG

    About Eltrombopag

    Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.

    Promacta Manufacturers

    A Promacta manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Promacta, including repackagers and relabelers. The FDA regulates Promacta manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Promacta API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Promacta manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Promacta Suppliers

    A Promacta supplier is an individual or a company that provides Promacta active pharmaceutical ingredient (API) or Promacta finished formulations upon request. The Promacta suppliers may include Promacta API manufacturers, exporters, distributors and traders.

    click here to find a list of Promacta suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Promacta USDMF

    A Promacta DMF (Drug Master File) is a document detailing the whole manufacturing process of Promacta active pharmaceutical ingredient (API) in detail. Different forms of Promacta DMFs exist exist since differing nations have different regulations, such as Promacta USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Promacta DMF submitted to regulatory agencies in the US is known as a USDMF. Promacta USDMF includes data on Promacta's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Promacta USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Promacta suppliers with USDMF on PharmaCompass.

    Promacta JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Promacta Drug Master File in Japan (Promacta JDMF) empowers Promacta API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Promacta JDMF during the approval evaluation for pharmaceutical products. At the time of Promacta JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Promacta suppliers with JDMF on PharmaCompass.

    Promacta KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Promacta Drug Master File in Korea (Promacta KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Promacta. The MFDS reviews the Promacta KDMF as part of the drug registration process and uses the information provided in the Promacta KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Promacta KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Promacta API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Promacta suppliers with KDMF on PharmaCompass.

    Promacta WC

    A Promacta written confirmation (Promacta WC) is an official document issued by a regulatory agency to a Promacta manufacturer, verifying that the manufacturing facility of a Promacta active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Promacta APIs or Promacta finished pharmaceutical products to another nation, regulatory agencies frequently require a Promacta WC (written confirmation) as part of the regulatory process.

    click here to find a list of Promacta suppliers with Written Confirmation (WC) on PharmaCompass.

    Promacta NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Promacta as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Promacta API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Promacta as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Promacta and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Promacta NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Promacta suppliers with NDC on PharmaCompass.

    Promacta GMP

    Promacta Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Promacta GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Promacta GMP manufacturer or Promacta GMP API supplier for your needs.

    Promacta CoA

    A Promacta CoA (Certificate of Analysis) is a formal document that attests to Promacta's compliance with Promacta specifications and serves as a tool for batch-level quality control.

    Promacta CoA mostly includes findings from lab analyses of a specific batch. For each Promacta CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Promacta may be tested according to a variety of international standards, such as European Pharmacopoeia (Promacta EP), Promacta JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Promacta USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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