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    Chemistry

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    Also known as: 25655-41-8, Povidone-iodine, Betadine, Isodine, Pvp iodine, Pvp-iodine
    Molecular Formula
    C6H9I2NO
    Molecular Weight
    364.95  g/mol
    InChI Key
    CPKVUHPKYQGHMW-UHFFFAOYSA-N
    Povidone Iodine
    An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.
    1 2D Structure

    Povidone Iodine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-ethenylpyrrolidin-2-one;molecular iodine
    2.1.2 InChI
    InChI=1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;
    2.1.3 InChI Key
    CPKVUHPKYQGHMW-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C=CN1CCCC1=O.II
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Alphadine

    2. Alphadines

    3. Betadine

    4. Betadines

    5. Betaisodona

    6. Disadine

    7. Disadines

    8. Isodine

    9. Isodines

    10. Pharmadine

    11. Pharmadines

    12. Polyvinylpyrrolidone Iodine

    13. Polyvinylpyrrolidone Iodines

    14. Povidone-iodine

    15. Povidone-iodines

    16. Providine

    17. Providines

    18. Pvp Iodine

    19. Pvp-i

    20. Pvp-iodine

    21. Pvp-iodines

    2.2.2 Depositor-Supplied Synonyms

    1. 25655-41-8

    2. Povidone-iodine

    3. Betadine

    4. Isodine

    5. Pvp Iodine

    6. Pvp-iodine

    7. Pvp-i

    8. Isobetadyne

    9. Bridine

    10. Disphex

    11. Povadyne

    12. Ultradine

    13. Efo-dine

    14. Iodopoly(vinyl Pyrrolidinone)

    15. 1-ethenylpyrrolidin-2-one;molecular Iodine

    16. Nsc26245

    17. 2-pyrrolidinone, 1-ethenyl-, Homopolymer, Compd. With Iodineother Ca Index Names:iodine, Compd. With 1-ethenyl-2-pyrrolidinone Homopolymer

    18. Iodine-poly(vinylpyrrolidinone)

    19. Poly(vinylpyrrolidinone) Iodide

    20. Iodinated Poly(vinylpyrrolidone)

    21. Poly(vinylpyrrolidone)-iodine Adduct

    22. Poly(vinylpyrrolidinone)-iodine Complex

    23. Poly(vinylpyrrolidone) - Iodine Complex

    24. Polyvinylpyrrolidone Compound With Iodine

    25. Povidone.iodine

    26. 1-ethenyl-2-pyrrolidinone Homopolymer Compound With Iodine

    27. Molecular Iodine; 1-vinylpyrrolidin-2-one

    28. 1-ethenylpyrrolidin-2-one; Molecular Iodine

    29. Povidone Iodine-ip, 9-12%

    30. Schembl1652685

    31. Bcp28568

    32. Nsc28655

    33. Mfcd00084483

    34. Nsc-26245

    35. Nsc-28655

    36. Akos015898248

    37. Polyvinylpyrrolidone-iodinecomplex

    38. 1-ethenyl-2-pyrrolidinone; Molecular Iodine

    39. Ft-0655804

    40. 2-pyrrolidinone, Polymers, Compd. With Iodine

    41. A16118

    42. 2-pyrrolidinone, Homopolymer, Compd. With Iodine

    43. A817952

    44. Q241516

    45. 1-vinylpyrrolidin-2-one Compound With Diiodine (1:1)

    46. Poly[1-(2-oxo-1-pyrrolidinyl)ethylene]iodine Complex

    47. Povidone (iodinated), European Pharmacopoeia (ep) Reference Standard

    2.3 Create Date
    2005-03-26
    3 Chemical and Physical Properties
    Molecular Weight 364.95 g/mol
    Molecular Formula C6H9I2NO
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count1
    Exact Mass364.87736 g/mol
    Monoisotopic Mass364.87736 g/mol
    Topological Polar Surface Area20.3 Ų
    Heavy Atom Count10
    Formal Charge0
    Complexity120
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 4  
    Drug NameBetadine
    PubMed HealthPovidone Iodine (Into the eye)
    Drug ClassesAntiseptic
    Drug LabelPovidone-Iodine is a broad-spectrum microbicide with the chemical formulas:2-pyrrolidinone, 1- ethenyl-, homopolymer, compound with iodine; 1-vinyl-2-pyrrolidinone polymer, compound with iodine. The structural formula is as follows:BETADINE 5% Ster...
    Active IngredientPovidone-iodine
    Dosage FormSolution/drops
    RouteOphthalmic
    Strength5%
    Market StatusPrescription
    CompanyAlcon Pharms

    2 of 4  
    Drug NamePovidone iodine
    PubMed HealthPovidone Iodine (Into the eye)
    Drug ClassesAntiseptic
    Drug LabelOther InformationStore below 98F/37C avoid direct heat and sunlight...
    Active IngredientPovidone-iodine
    Dosage FormSolution
    RouteTopical
    Strength1%
    Market StatusOver the Counter
    CompanyAllegiance Hlthcare

    3 of 4  
    Drug NameBetadine
    PubMed HealthPovidone Iodine (Into the eye)
    Drug ClassesAntiseptic
    Drug LabelPovidone-Iodine is a broad-spectrum microbicide with the chemical formulas:2-pyrrolidinone, 1- ethenyl-, homopolymer, compound with iodine; 1-vinyl-2-pyrrolidinone polymer, compound with iodine. The structural formula is as follows:BETADINE 5% Ster...
    Active IngredientPovidone-iodine
    Dosage FormSolution/drops
    RouteOphthalmic
    Strength5%
    Market StatusPrescription
    CompanyAlcon Pharms

    4 of 4  
    Drug NamePovidone iodine
    PubMed HealthPovidone Iodine (Into the eye)
    Drug ClassesAntiseptic
    Drug LabelOther InformationStore below 98F/37C avoid direct heat and sunlight...
    Active IngredientPovidone-iodine
    Dosage FormSolution
    RouteTopical
    Strength1%
    Market StatusOver the Counter
    CompanyAllegiance Hlthcare

    4.2 Therapeutic Uses

    Anti-Infective Agents, Local

    National Library of Medicine's Medical Subject Headings online file (MeSH, 2014)

    Povidone-iodine is an iodophore that is used as a disinfectant and antiseptic mainly for the treatment of contaminated wounds and pre-operative preparation of the skin and mucous membranes as well as for disinfection of equipment.

    SWEETMAN, S.C. (ed.) Martindale-The Complete Drug Reference. 36th ed. London: The Pharmaceutical Press, 2009., p. 1659

    BETADINE 5% Sterile Ophthalmic Prep Solution for the eye is indicated for prepping of the periocular region (lids, brow, and cheek) and irrigation of the ocular surface (cornea, conjunctiva, and palpebral fornices).

    NIH; DailyMed. Current Medication Information for BETADINE- povidone-iodine solution (Revised: July 2011). Available from, as of October 14, 2014: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b026de1b-9949-4557-ac49-c7b0038c24cd

    4.3 Drug Warning

    No studies are available in patients with thyroid disorders; therefore, caution is advised in using BETADINE 5% Sterile Ophthalmic Prep Solution in these patients due to the possibility of iodine absorption.

    NIH; DailyMed. Current Medication Information for BETADINE- povidone-iodine solution (Revised: July 2011). Available from, as of October 14, 2014: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b026de1b-9949-4557-ac49-c7b0038c24cd

    Because of the potential for serious adverse reactions in nursing infants from BETADINE 5% Sterile Ophthalmic Prep Solution, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

    NIH; DailyMed. Current Medication Information for BETADINE- povidone-iodine solution (Revised: July 2011). Available from, as of October 14, 2014: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b026de1b-9949-4557-ac49-c7b0038c24cd

    FDA Pregnancy Risk Category: C /RISK CANNOT BE RULED OUT. Adequate, well controlled human studies are lacking, and animal studies have shown risk to the fetus or are lacking as well. There is a chance of fetal harm if the drug is given during pregnancy; but the potential benefits may outweigh the potential risk./

    NIH; DailyMed. Current Medication Information for BETADINE- povidone-iodine solution (Revised: July 2011). Available from, as of October 14, 2014: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b026de1b-9949-4557-ac49-c7b0038c24cd

    For external use only. Not for intraocular injection or irrigation.

    NIH; DailyMed. Current Medication Information for BETADINE- povidone-iodine solution (Revised: July 2011). Available from, as of October 14, 2014: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b026de1b-9949-4557-ac49-c7b0038c24cd

    For more Drug Warnings (Complete) data for Povidone-iodine (9 total), please visit the HSDB record page.

    4.4 Drug Indication

    For topical application in the treatment and prevention of infection in wounds.

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Povidone iodine is a kind of iodine disinfectant which directly cause in vivo protein denaturation, precipitation of bacteria, and further resulting in the death of pathogenic microorganisms. Therefore, it is effective in disinfection and sterilization. It can kill viruses, bacteria, spores, fungi, and protozoa with low toxicity to human. Povidone-iodine aqueous solution has strong pharmacological activity against Staphylococcus aureus, Neisseria gonorrhoeae, Pseudomonas aeruginosa, syphilis, hepatitis B virus, HIV, and Trichomonas vaginalis. Povidone iodine gel is a gynecological topical semi-mobile colloidal agent made by povidone iodine and hydrophilic matrix. It is a system for maintaining its sustained release. Owing to the continuous release of free iodine, it can enable the skin and mucous membranes to maintain a certain effective concentration of iodine for killing bacteria. It is mainly used for gynecological vaginal infection. It exerted its effect through being miscible with vaginal secretions and further killing the inside pathogenic microorganisms, and thus blocking the spread of sexually transmitted diseases and invasion, as well as treating other infected vaginal diseases caused by other kinds of bacteria. Published reports on the in vitro antimicrobial efficacy of iodophors demonstrate that iodophors are bactericidal, mycobactericidal, and virucidal but can require prolonged contact times to kill certain fungi and bacterial spores. Three brands of povidone-iodine solution have demonstrated more rapid kill (seconds to minutes) of S. aureus and M. chelonae at a 1:100 dilution than did the stock solution. The virucidal activity of 75150 ppm available iodine was demonstrated against seven viruses. Other investigators have questioned the efficacy of iodophors against poliovirus in the presence of organic matter and rotavirus in distilled or tapwater. Manufacturers' data demonstrate that commercial iodophors are not sporicidal, but they are tuberculocidal, fungicidal, virucidal, and bactericidal at their recommended use-dilution.

    5.2 MeSH Pharmacological Classification

    Anti-Infective Agents, Local

    Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects. (See all compounds classified as Anti-Infective Agents, Local.)

    5.3 ATC Code

    D - Dermatologicals

    D08 - Antiseptics and disinfectants

    D08A - Antiseptics and disinfectants

    D08AG - Iodine products

    D08AG02 - Povidone-iodine

    D - Dermatologicals

    D09 - Medicated dressings

    D09A - Medicated dressings

    D09AA - Medicated dressings with antiinfectives

    D09AA09 - Povidone-iodine

    D - Dermatologicals

    D11 - Other dermatological preparations

    D11A - Other dermatological preparations

    D11AC - Medicated shampoos

    D11AC06 - Povidone-iodine

    G - Genito urinary system and sex hormones

    G01 - Gynecological antiinfectives and antiseptics

    G01A - Antiinfectives and antiseptics, excl. combinations with corticosteroids

    G01AX - Other antiinfectives and antiseptics

    G01AX11 - Povidone-iodine

    R - Respiratory system

    R02 - Throat preparations

    R02A - Throat preparations

    R02AA - Antiseptics

    R02AA15 - Povidone-iodine

    S - Sensory organs

    S01 - Ophthalmologicals

    S01A - Antiinfectives

    S01AX - Other antiinfectives

    S01AX18 - Povidone-iodine

    5.4 Absorption, Distribution and Excretion

    Absorption

    Povidone-Iodine is intended for topical application and is not absorbed.

    Route of Elimination

    Povidone-Iodine is intended for topical application and is not eliminated.

    Volume of Distribution

    Povidone-Iodine is intended for topical application and has no volume of distribution.

    Clearance

    Povidone-Iodine is intended for topical application and is not eliminated.

    Topical application of povidone iodine on the umbilical cord and normal intact skin of newborn infants resulted in significantly elevated plasma iodine levels. High iodine levels were also found in two neonates who had povidone iodine applied to denuded skin. No significant alteration in thyroid function was seen. The possible toxic manifestations of high plasma iodine levels are discussed.

    PMID:909027 Pyati SP et al; J Pediatr. 91 (5): 825-8 (1977)

    In 12 nonpregnant women, total iodine, protein-bound iodine, inorganic iodine, and thyroxine values were measured in serum before and 15, 30, 45 or 60 minutes after a two-minute vaginal disinfection with povidone-iodine (Betadine). Only 15 minutes after application, serum iodine levels were raised and remained significantly elevated 30, 45 and 60 minutes after disinfection. Serum concentrations of total iodine and inorganic iodine were increased up to fivefold to 15-fold, respectively; during the relative short period of observation, thyroxine levels were not altered.

    PMID:7431610 Vorherr H et al; JAMA. 244 (23): 2628-9 (1980)

    5.5 Metabolism/Metabolites

    Povidone-Iodine is not absorbed or metabolized.

    5.6 Biological Half-Life

    Povidone-Iodine is intended for topical application and is not eliminated.

    5.7 Mechanism of Action

    Povidone-iodine is called iodophore which means povidone acts as a carrier of iodine. Iodine is considered as the active moiety that mediates microbicidal actions. When released from the complex, free iodine (I2) penetrates the cell wall of microorganisms quickly, and the lethal effects are believed to result from disruption of protein and nucleic acid structure and synthesis. While the full mechanism of action is not fully elucidated, iodine is thought to inhibit vital bacterial cellular mechanisms and structures, and oxidizes nucleotides fatty or amino acids in bacterial cell membranes. Additionally, free iodine disrupts the function of the cytosolic enzymes involved in the respiratory chain, causing them to become denatured and deactivated. _In vitro_ evidence suggests that iodine also counteracts inflammation elicited by both pathogens and the host response via multifactorial effects. In hosts, povidone-iodine was demonstrated to modulate the redox potential, inhibit the release of inflammatory mediators such as TNF- and -galactosidase, inhibit metalloproteinase production, and potentiate the healing signals from pro-inflammatory cytokines by activation of monocytes, T-lymphocytes, and macrophages, _in vitro_.

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      Povidone, iodinated

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      CEP 2025-012 - Rev 00
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      Certificate Number : CEP 2025-012 - Rev 00

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      Issue Date : 2025-07-22

      Type : Chemical

      Substance Number : 1142

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        Certificate Number : R1-CEP 2005-007 - Rev 01

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        Substance Number : 1142

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        Povidone, iodinated

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        R0-CEP 2009-166 - Rev 00
        Withdrawn by EDQM F...
        Chemical
        2011-06-06
        2015-03-19
        1142
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        03

        HANGZHOU SUNFLOWER TECHNOLOGY DEVEL...

        China
        Arvo
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        HANGZHOU SUNFLOWER TECHNOLOGY DEVEL...

        China
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        Povidone, Iodinated

        Certificate Number : R0-CEP 2009-166 - Rev 00

        Status : Withdrawn by EDQM Failure to CEP pro...

        Issue Date : 2011-06-06

        Type : Chemical

        Substance Number : 1142

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        CNSG ANHUI HONG SIFANG CO., LTD. He...

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          R1-CEP 2016-278 - Rev 00
          Valid
          Chemical
          2023-02-01
          1142
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          CNSG ANHUI HONG SIFANG CO., LTD. He...

          China
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          SHANGHAI YUKING WATER SOLUBLE MATER...

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            Povidone, iodinated

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            CEP 2022-428 - Rev 00
            Valid
            Chemical
            2024-05-15
            1142
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            SHANGHAI YUKING WATER SOLUBLE MATER...

            China
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            STAR-TECH & JRS SPECIALTY PRODUCTS ...

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              Povidone, K90

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              R1-CEP 2016-046 - Rev 00
              Valid
              Chemical
              2021-05-05
              685
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              STAR-TECH & JRS SPECIALTY PRODUCTS ...

              China
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              The Graymor Chemical Hamburg GmbH H...

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                Povidone, iodinated

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                R1-CEP 1999-115 - Rev 02
                Valid
                Chemical
                2010-08-05
                1142
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                07

                The Graymor Chemical Hamburg GmbH H...

                Germany
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                SYNVENT NINGXIA CO.,LTD. Yinchuan C...

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                Povidone, iodinated

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                CEP 2025-601 - Rev 00
                Valid
                Chemical
                2026-04-08
                1142
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                SYNVENT NINGXIA CO.,LTD. Yinchuan C...

                Country
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                SYNVENT NINGXIA CO.,LTD. Yinchuan C...

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                Povidone, Iodinated

                Certificate Number : CEP 2025-601 - Rev 00

                Status : Valid

                Issue Date : 2026-04-08

                Type : Chemical

                Substance Number : 1142

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                JDMF

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                01

                Ashland Inc.

                U.S.A
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                Ashland Inc.

                U.S.A
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                PVP IODINE

                Registration Number : 218MF10438

                Registrant's Address : 8145 Blazer Drive, Wilmington, DE, 19808, United States

                Initial Date of Registration : 2006-04-27

                Latest Date of Registration : 2024-05-29

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                02

                BASF Corporation

                Germany
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                BASF Corporation

                Germany
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                Povidone-iodine (PVP-Iodine)

                Registration Number : 217MF10985

                Registrant's Address : 100 Park Avenue, Florham Park, New Jersey, 07932, United States of America

                Initial Date of Registration : 2005-11-21

                Latest Date of Registration : 2016-05-17

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                03

                Glide Chem Pvt. Ltd.

                India
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                Glide Chem Pvt. Ltd.

                India
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                Povidone-iodine (PVP-IODINE)

                Registration Number : 229MF10087

                Registrant's Address : S-39, Rajouri Garden, New Delhi-110027, India

                Initial Date of Registration : 2017-04-25

                Latest Date of Registration : 2017-04-25

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                04

                Marcus Research Laboratory, Inc.

                U.S.A
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                Marcus Research Laboratory, Inc.

                U.S.A
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                Japanese Pharmacopoeia Povidone-Iodine (for manufacturing purposes only)

                Registration Number : 218MF10060

                Registrant's Address : 1820 Delmar Blvd. , St. Louis, MO 63103, USA

                Initial Date of Registration : 2006-01-27

                Latest Date of Registration : 2010-03-19

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                NDC API

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                01

                BASF Corporation

                Germany
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                BASF Corporation

                Germany
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                POVIDONE-IODINE

                NDC Package Code : 70177-0002

                Start Marketing Date : 2010-01-11

                End Marketing Date : 2026-12-31

                Dosage Form (Strength) : POWDER (1kg/kg)

                Marketing Category : BULK INGREDIENT

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                02

                Eskay Iodine Private Limited

                India
                Arvo
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                Eskay Iodine Private Limited

                India
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                POVIDONE-IODINE

                NDC Package Code : 70115-0004

                Start Marketing Date : 2017-05-05

                End Marketing Date : 2026-12-31

                Dosage Form (Strength) : POWDER (1kg/kg)

                Marketing Category : BULK INGREDIENT

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                03

                ISP Chemicals LLC

                U.S.A
                Arvo
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                ISP Chemicals LLC

                U.S.A
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                POVIDONE-IODINE

                NDC Package Code : 21222-001

                Start Marketing Date : 2012-02-23

                End Marketing Date : 2026-12-31

                Dosage Form (Strength) : POWDER (100kg/100kg)

                Marketing Category : BULK INGREDIENT

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                04

                Marcus Research Laboratory, Inc.

                U.S.A
                Arvo
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                Marcus Research Laboratory, Inc.

                U.S.A
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                POVIDONE-IODINE

                NDC Package Code : 44242-100

                Start Marketing Date : 1981-04-02

                End Marketing Date : 2026-12-31

                Dosage Form (Strength) : POWDER (1kg/kg)

                Marketing Category : BULK INGREDIENT

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                05

                Spectrum Laboratory Products, Inc.

                U.S.A
                Arvo
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                Spectrum Laboratory Products, Inc.

                U.S.A
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                POVIDONE-IODINE

                NDC Package Code : 49452-5970

                Start Marketing Date : 1990-04-01

                End Marketing Date : 2026-12-31

                Dosage Form (Strength) : POWDER (1g/g)

                Marketing Category : BULK INGREDIENT

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                06

                Thatcher Company

                U.S.A
                Arvo
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                Thatcher Company

                U.S.A
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                POVIDONE-IODINE

                NDC Package Code : 30032-551

                Start Marketing Date : 2013-03-29

                End Marketing Date : 2026-12-31

                Dosage Form (Strength) : POWDER (1kg/kg)

                Marketing Category : DRUG FOR FURTHER PROCESSING

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                07

                Unilab Chemicals and Pharmaceutical...

                India
                Arvo
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                Unilab Chemicals and Pharmaceutical...

                India
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                POVIDONE-IODINE

                NDC Package Code : 25119-3000

                Start Marketing Date : 2017-05-11

                End Marketing Date : 2026-12-31

                Dosage Form (Strength) : POWDER (1kg/kg)

                Marketing Category : BULK INGREDIENT

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                08

                Zen Chemicals Private Limited

                Japan
                Arvo
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                Zen Chemicals Private Limited

                Japan
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                POVIDONE-IODINE

                NDC Package Code : 72742-6000

                Start Marketing Date : 2023-10-20

                End Marketing Date : 2026-12-31

                Dosage Form (Strength) : POWDER (1kg/kg)

                Marketing Category : BULK INGREDIENT

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                Listed Suppliers

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                01

                Jai Radhe Sales

                India
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                Virtual BoothJai Radhe Sales is your partner for all your sourcing needs.

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                Povidone-Iodine

                About the Company : Jai Radhe Sales, founded in 1999, is a global distributor specializing in high-quality pharmaceutical ingredients from India. It offers complete sourcing solutions, technical and r...

                Jai Radhe Sales, founded in 1999, is a global distributor specializing in high-quality pharmaceutical ingredients from India. It offers complete sourcing solutions, technical and regulatory support, and strives for global standards. Known for quality and affordability, it has established a niche through innovative methods and exports to nearly every continent. Note: Product(s) under patent(s) are offered only for R&D purposes as per the Patent Act & not for commercial sale.
                Jai Radhe Sales

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                02

                Tenatra Exports

                India
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                Virtual BoothTenatra connects Indian manufacturers with global buyers through active partners in Germany, Switzerland, Belgium, Spain & Turkey.

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                Povidone-Iodine

                About the Company : Tenatra International was established as a proprietorship firm in 1999. It got off to a very good start, supporting clients in the United States, Mexico and Europe. As business opp...

                Tenatra International was established as a proprietorship firm in 1999. It got off to a very good start, supporting clients in the United States, Mexico and Europe. As business opportunities grew, it was felt that the proprietorship firm had outlived its usefulness and that it needed a corporate structure. So, Tenatra Exports Private Limited was incorporated in 2002. Since then, the company has come a long way, gaining valuable experience and knowledge in the fields of chemicals and pharmaceuticals in India. Note: Product(s) under patent(s) are offered only for R&D purposes as per the Patent Act & not for commercial sale.
                Tenatra

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                03

                BASF

                Germany
                Arvo
                Not Confirmed
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                BASF

                Germany
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                PVP Iodine

                About the Company : We create chemistry for a sustainable future. In line with our corporate purpose, around 112,000 employees contribute to the success of our customers in nearly all sectors and alm...

                We create chemistry for a sustainable future. In line with our corporate purpose, around 112,000 employees contribute to the success of our customers in nearly all sectors and almost every country in the world. Our broad portfolio ranges from chemicals, plastics, performance products and crop protection products to oil and gas. In 2015, BASF posted sales of €70 billion and income from operations before special items of approximately €6.7 billion. We combine economic success with environmental protection and social responsibility. Through research and innovation, we support our customers in nearly every industry.
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                04

                Kenoor Organics

                India
                Arvo
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                Kenoor Organics

                India
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                Povidone Iodine

                About the Company : Over a brief period, KOHINOOR GROUP has experienced substantial growth, evolving into an integrated conglomerate involved in the development and manufacturing of Dyestuffs, Pigment...

                Over a brief period, KOHINOOR GROUP has experienced substantial growth, evolving into an integrated conglomerate involved in the development and manufacturing of Dyestuffs, Pigments, and Active Pharmaceutical Ingredients (APIs). The group presently operates 14 manufacturing units. In 2003, KOHINOOR GROUP made a strategic decision to diversify and expand its business by venturing into pharmaceutical manufacturing. The focus was on a broad spectrum of products, including Antiseptics, Disinfectants and Preservatives within the Pharmaceuticals Division.Presently, KENOOR ORGANICS, is recognized as a GMP & GLP Certified Company.
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                05

                Life Pharma Chem

                India
                Arvo
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                Life Pharma Chem

                India
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                Povidone Iodine

                About the Company : Life Pharma Chem, established in 2012 in Rajkot, Gujarat, is a trusted partnership firm engaged in the manufacturing, importing, and exporting of high-quality Povidone Iodine Powde...

                Life Pharma Chem, established in 2012 in Rajkot, Gujarat, is a trusted partnership firm engaged in the manufacturing, importing, and exporting of high-quality Povidone Iodine Powder. We are committed to delivering quality chemicals at genuine rates, backed by a strong infrastructure. Our mission is to safeguard future generations by embracing environmentally responsible practices. Guided by our core values of Quality, Consistency, and Reliability, we aim to exceed customer expectations and contribute positively to our community and environment.
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                06

                Progress Life Sciences

                India
                Arvo
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                Progress Life Sciences

                India
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                Povidone Iodine

                About the Company : Progress is a company led by professionals, established by technocrats with a vision for global business expansion. Our headquarters are located in Vashi, Mumbai, with a manufactur...

                Progress is a company led by professionals, established by technocrats with a vision for global business expansion. Our headquarters are located in Vashi, Mumbai, with a manufacturing unit in Pune, Maharashtra. We operate in five key verticals, including Active Pharmaceutical Ingredients (APIs), Intermediates & Specialty Chemicals, and Finished Dosage Formulations. Our approach is centered around innovation, aiming to excel in our segment. Backward integration of API and FDF serves as key growth drivers, and we employ flow chemistry and micro reactors for pioneering innovations.
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                07

                Proto Chemical Industries

                India
                Arvo
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                Proto Chemical Industries

                India
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                Povidone Iodine

                About the Company : We are counted among one of the leading processors and suppliers engaged in offering Iodine Salts, Hydroxide Powder and other Chemicals. Our products are processed employing suprem...

                We are counted among one of the leading processors and suppliers engaged in offering Iodine Salts, Hydroxide Powder and other Chemicals. Our products are processed employing supreme quality ingredients, latest machinery and methods. Further, with our supreme quality products, we have attained certifications like GMP and FDA. The products offered by us are used in industries like rubber, pharmaceutical, food & beverage, manufacturing nutritional products, battery industry and laboratories. We offer these products to our customers at market leading prices as per their demands.Potassium Iodide Stabilized Grade Iodine Compounds, Feed Supplement
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                08

                Qingdao Qingmei Biotech

                China
                Arvo
                Not Confirmed
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                Qingdao Qingmei Biotech

                China
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                Povidone Iodine

                About the Company : QINGDAO QINGMEI BIOTECH(hereinafter referred to as Qingmei) is a specialized pharmaceutical company founded by DAYON INTERNATIONAL HOLDING LIMITED, which is to expand international...

                QINGDAO QINGMEI BIOTECH(hereinafter referred to as Qingmei) is a specialized pharmaceutical company founded by DAYON INTERNATIONAL HOLDING LIMITED, which is to expand international business and strategic cooperation with suppliers. The company is located in the beautiful coastal city of Qingdao, near City Hall and the May Fourth Square, and also close to the port, so that it has convenient traffic conditions for trade. The company's business focuses on the development and promotion of the pharmaceutical chemicals, animal health, food additives, plant extracts, cosmetic raw materials, intermediates and other fine chemicals.
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                09

                Salvi Chemical Industries

                India
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                Salvi Chemical Industries

                India
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                Povidone Iodine

                About the Company : Salvi Chemical Industries Ltd. founded in 1978, is India's leading manufacturer and exporter of chemical and pharmaceutical products that includes nutritional products, intermediat...

                Salvi Chemical Industries Ltd. founded in 1978, is India's leading manufacturer and exporter of chemical and pharmaceutical products that includes nutritional products, intermediates, bulk drugs, veterinary products, sweetners, quinolines, triazole and selenium products. Salvi Chemical Industries Ltd. is the largest manufacturers of iron products (One stop for Iron Products) across the globe. We are also one of the largest manufacturers of Iodine and Quinoline products. With a rich tradition of unwavering quality and reliability, SCIL brings together a unique blend of modern, value-added research and deep knowledge of the chemical industry.
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                Samrat Pharmachem

                India
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                Samrat Pharmachem

                India
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                Povidone Iodine

                About the Company : Samrat Pharmachem Limited was incorporated on 16th June, 1992, at Ankleshwar in Gujarat State of India. It was promoted by Mr. Lalit Mehta & Mr. Rajesh Mehta. The Company is curre...

                Samrat Pharmachem Limited was incorporated on 16th June, 1992, at Ankleshwar in Gujarat State of India. It was promoted by Mr. Lalit Mehta & Mr. Rajesh Mehta. The Company is currently manufacturing different IODINE derivatives. The finished products produced by the company are used in various industries like Pharmaceuticals, Chemicals, Food, Fertilizer, Cattle Feed, Salt etc. The products of the company are well received in Indian & Foreign markets. The company is a public limited company & its shares are listed & traded on Bombay Stock Exchange & other bourses of India.
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                ABOUT THIS PAGE

                Looking for 25655-41-8 / Povidone Iodine API manufacturers, exporters & distributors?

                Povidone Iodine manufacturers, exporters & distributors 1

                39

                PharmaCompass offers a list of Povidone Iodine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Povidone Iodine manufacturer or Povidone Iodine supplier for your needs.

                Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Povidone Iodine manufacturer or Povidone Iodine supplier.

                API | Excipient name

                Povidone Iodine

                Synonyms

                25655-41-8, Povidone-iodine, Betadine, Isodine, Pvp iodine, Pvp-iodine

                Cas Number

                25655-41-8

                About Povidone Iodine

                An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.

                POVIDONE IODINE (API) Manufacturers

                A POVIDONE IODINE (API) manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of POVIDONE IODINE (API), including repackagers and relabelers. The FDA regulates POVIDONE IODINE (API) manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. POVIDONE IODINE (API) API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

                click here to find a list of POVIDONE IODINE (API) manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

                POVIDONE IODINE (API) Suppliers

                A POVIDONE IODINE (API) supplier is an individual or a company that provides POVIDONE IODINE (API) active pharmaceutical ingredient (API) or POVIDONE IODINE (API) finished formulations upon request. The POVIDONE IODINE (API) suppliers may include POVIDONE IODINE (API) API manufacturers, exporters, distributors and traders.

                click here to find a list of POVIDONE IODINE (API) suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

                POVIDONE IODINE (API) USDMF

                A POVIDONE IODINE (API) DMF (Drug Master File) is a document detailing the whole manufacturing process of POVIDONE IODINE (API) active pharmaceutical ingredient (API) in detail. Different forms of POVIDONE IODINE (API) DMFs exist exist since differing nations have different regulations, such as POVIDONE IODINE (API) USDMF, ASMF (EDMF), JDMF, CDMF, etc.

                A POVIDONE IODINE (API) DMF submitted to regulatory agencies in the US is known as a USDMF. POVIDONE IODINE (API) USDMF includes data on POVIDONE IODINE (API)'s chemical properties, information on the facilities and procedures used, and details about packaging and storage. The POVIDONE IODINE (API) USDMF is kept confidential to protect the manufacturer’s intellectual property.

                click here to find a list of POVIDONE IODINE (API) suppliers with USDMF on PharmaCompass.

                POVIDONE IODINE (API) JDMF

                The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

                The POVIDONE IODINE (API) Drug Master File in Japan (POVIDONE IODINE (API) JDMF) empowers POVIDONE IODINE (API) API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

                PMDA reviews the POVIDONE IODINE (API) JDMF during the approval evaluation for pharmaceutical products. At the time of POVIDONE IODINE (API) JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

                click here to find a list of POVIDONE IODINE (API) suppliers with JDMF on PharmaCompass.

                POVIDONE IODINE (API) KDMF

                In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

                Pharmaceutical companies submit a POVIDONE IODINE (API) Drug Master File in Korea (POVIDONE IODINE (API) KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of POVIDONE IODINE (API). The MFDS reviews the POVIDONE IODINE (API) KDMF as part of the drug registration process and uses the information provided in the POVIDONE IODINE (API) KDMF to evaluate the safety and efficacy of the drug.

                After submitting a POVIDONE IODINE (API) KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their POVIDONE IODINE (API) API can apply through the Korea Drug Master File (KDMF).

                click here to find a list of POVIDONE IODINE (API) suppliers with KDMF on PharmaCompass.

                POVIDONE IODINE (API) CEP

                A POVIDONE IODINE (API) CEP of the European Pharmacopoeia monograph is often referred to as a POVIDONE IODINE (API) Certificate of Suitability (COS). The purpose of a POVIDONE IODINE (API) CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of POVIDONE IODINE (API) EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of POVIDONE IODINE (API) to their clients by showing that a POVIDONE IODINE (API) CEP has been issued for it. The manufacturer submits a POVIDONE IODINE (API) CEP (COS) as part of the market authorization procedure, and it takes on the role of a POVIDONE IODINE (API) CEP holder for the record. Additionally, the data presented in the POVIDONE IODINE (API) CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the POVIDONE IODINE (API) DMF.

                A POVIDONE IODINE (API) CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. POVIDONE IODINE (API) CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

                click here to find a list of POVIDONE IODINE (API) suppliers with CEP (COS) on PharmaCompass.

                POVIDONE IODINE (API) WC

                A POVIDONE IODINE (API) written confirmation (POVIDONE IODINE (API) WC) is an official document issued by a regulatory agency to a POVIDONE IODINE (API) manufacturer, verifying that the manufacturing facility of a POVIDONE IODINE (API) active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting POVIDONE IODINE (API) APIs or POVIDONE IODINE (API) finished pharmaceutical products to another nation, regulatory agencies frequently require a POVIDONE IODINE (API) WC (written confirmation) as part of the regulatory process.

                click here to find a list of POVIDONE IODINE (API) suppliers with Written Confirmation (WC) on PharmaCompass.

                POVIDONE IODINE (API) NDC

                National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing POVIDONE IODINE (API) as an active pharmaceutical ingredient (API).

                Finished drug products

                The FDA updates the NDC directory daily. The NDC numbers for POVIDONE IODINE (API) API and other APIs are published in this directory by the FDA.

                Unfinished drugs

                The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

                Pharmaceutical companies that manufacture POVIDONE IODINE (API) as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

                Compounded drug products

                The NDC directory also contains data on finished compounded human drug products that contain POVIDONE IODINE (API) and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a POVIDONE IODINE (API) NDC to their finished compounded human drug products, they may choose to do so.

                click here to find a list of POVIDONE IODINE (API) suppliers with NDC on PharmaCompass.

                POVIDONE IODINE (API) GMP

                POVIDONE IODINE (API) Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

                GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

                PharmaCompass offers a list of POVIDONE IODINE (API) GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right POVIDONE IODINE (API) GMP manufacturer or POVIDONE IODINE (API) GMP API supplier for your needs.

                POVIDONE IODINE (API) CoA

                A POVIDONE IODINE (API) CoA (Certificate of Analysis) is a formal document that attests to POVIDONE IODINE (API)'s compliance with POVIDONE IODINE (API) specifications and serves as a tool for batch-level quality control.

                POVIDONE IODINE (API) CoA mostly includes findings from lab analyses of a specific batch. For each POVIDONE IODINE (API) CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

                POVIDONE IODINE (API) may be tested according to a variety of international standards, such as European Pharmacopoeia (POVIDONE IODINE (API) EP), POVIDONE IODINE (API) JP (Japanese Pharmacopeia) and the US Pharmacopoeia (POVIDONE IODINE (API) USP).

                Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
                For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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