Find Piperaquine Phosphate manufacturers, exporters & distributors on PharmaCompass

Piperaquine Phosphate

Piperaquine Phosphate

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

11 API Suppliers, 5 EU WC, 8 Listed Suppliers

PRICE INFORMATION

API Reference Price, API Exports, API Imports

INTERMEDIATES

1 Suppliers

1 Suppliers

DOSSIERs // Finished Dosage Formulations

1 Dossiers, 1 Listed Dossiers

MARKET PLACE

3 APIs

3 APIs

REF. STANDARDS & IMPURITIES

6 Others

6 Others

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

EU WC

Listed Suppliers

API REF. PRICE (USD / KG)

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 85547-56-4, 5a17bat3gk, Piperaquine (phosphate), Piperaquine phosphate (1:1), 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate, 1215783-76-8

Molecular Formula

C₂₉H₃₅Cl₂N₆O₄P

Molecular Weight

633.5 g/mol

InChI Key

KATNPMSTHHZOTK-UHFFFAOYSA-N

FDA UNII

5A17BAT3GK

1 2D Structure

Piperaquine Phosphate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

7-chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline;phosphoric acid

2.1.2 InChI

InChI=1S/C29H32Cl2N6.H3O4P/c30-22-2-4-24-26(20-22)32-8-6-28(24)36-16-12-34(13-17-36)10-1-11-35-14-18-37(19-15-35)29-7-9-33-27-21-23(31)3-5-25(27)29;1-5(2,3)4/h2-9,20-21H,1,10-19H2;(H3,1,2,3,4)

2.1.3 InChI Key

KATNPMSTHHZOTK-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1CN(CCN1CCCN2CCN(CC2)C3=C4C=CC(=CC4=NC=C3)Cl)C5=C6C=CC(=CC6=NC=C5)Cl.OP(=O)(O)O

2.2 Other Identifiers

2.2.1 UNII

5A17BAT3GK

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 1,3-bis(1-(7-chloro-4'-quinolyl)-4'-piperazinyl)propane

2. Piperaquine

3. Piperaquine Phosphate (1:1)

4. Piperaquine Phosphate (1:4) Anhydrous

5. Piperaquine Tetraphosphate Anhydrous

6. Piperaquine Tetraphosphate Tetrahydrate

7. Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro-)

8. Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro-, Phosphate (1:1)

9. Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro-, Phosphate (1:4)

10. Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro-, Phosphate, Hydrate (1:4:4)

2.3.2 Depositor-Supplied Synonyms

1. 85547-56-4

2. 5a17bat3gk

3. Piperaquine (phosphate)

4. Piperaquine Phosphate (1:1)

5. 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) Phosphate

6. 1215783-76-8

7. Unii-5a17bat3gk

8. Chembl539666

9. Schembl16101632

10. Hy-b1896a

11. Ex-a400

12. Dtxsid601006108

13. Bcp11808

14. S5355

15. Akos015896507

16. Ccg-270293

17. Sb19151

18. As-10594

19. Cs-0014403

20. 951p979

21. A841358

22. 1,3-bis(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propane Phosphate

23. 1,3-bis(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propane Xphosphate

24. 1,3-bis(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propanephosphate

25. 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline)phosphate

26. Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro-, Phosphate

27. Phosphoric Acid--4,4'-[propane-1,3-diyldi(piperazine-4,1-diyl)]bis(7-chloroquinoline) (1/1)

28. Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro-, Phosphate (1:1)

2.4 Create Date

2005-08-09

3 Chemical and Physical Properties

Molecular Formula	C₂₉H₃₅Cl₂N₆O₄P
Molecular Weight	633.5 g/mol
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	6
Exact Mass	632.1834460 g/mol
Monoisotopic Mass	632.1834460 g/mol
Topological Polar Surface Area	117 Å²
Heavy Atom Count	42
Formal Charge	0
Complexity	704
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antimalarials

Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585) (See all compounds classified as Antimalarials.)