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1. 37338-80-0
2. (2,2'-bipyridine)-3,3',4,4'-tetrol, 1,1'-dioxide
3. 2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one
4. [2,2'-bipyridine]-3,3',4,4'-tetrol, 1,1'-dioxide
5. [2,2'-bipyridine]-3,3',4,4'-tetrol,1,1'-dioxide
6. Orellanine [hsdb]
7. Schembl388071
8. 082u1gsx3d
9. Chembl2152646
10. Chebi:190273
11. Zinc150339637
12. Q420527
13. 3,3',4,4'-tetrahydroxy-2,2'-bipyridyl-n,n'-dioxide
14. 3,3',4,4'-tetrahydroxy-2,2'-bipyridine-1,1'-dioxide
15. 2-(3,4-dihydroxy-1-oxidopyridin-1-ium-2-yl)-3,4-dihydroxypyridin-1-ium-1-olate
| Molecular Weight | 252.18 g/mol |
|---|---|
| Molecular Formula | C10H8N2O6 |
| XLogP3 | -1 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 1 |
| Exact Mass | 252.03823598 g/mol |
| Monoisotopic Mass | 252.03823598 g/mol |
| Topological Polar Surface Area | 122 Ų |
| Heavy Atom Count | 18 |
| Formal Charge | 0 |
| Complexity | 507 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
A woman suffering from acute tubulo-interstitial nephritis was admitted to the hospital ten days after deliberate intoxication by ingestion of Cortinarius orellanus. Orellanine, the main toxin responsible for orellanine poisoning, was detected in biological fluids and renal biopsies. It was assayed by direct spectrofluorimetry on two-dimensional thin-layer chromatograms after specific photodecomposition into orelline. The orellanine concentration was 6.12 mg/L in the plasma (10 days after ingestion). Orellanine levels in renal biopsies were 7 ug per 25 cu mm of the first biopsy (13 days after ingestion) and 24 ug per 8 cu mm of the second biopsy (6 months later).
PMID:2615804 Rapior S et al; Mycopathologia 108 (3): 155-61 (1989).
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PharmaCompass offers a list of Orellanine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Orellanine manufacturer or Orellanine supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Orellanine manufacturer or Orellanine supplier.
PharmaCompass also assists you with knowing the Orellanine API Price utilized in the formulation of products. Orellanine API Price is not always fixed or binding as the Orellanine Price is obtained through a variety of data sources. The Orellanine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Orellanine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Orellanine, including repackagers and relabelers. The FDA regulates Orellanine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Orellanine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Orellanine supplier is an individual or a company that provides Orellanine active pharmaceutical ingredient (API) or Orellanine finished formulations upon request. The Orellanine suppliers may include Orellanine API manufacturers, exporters, distributors and traders.
Orellanine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Orellanine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Orellanine GMP manufacturer or Orellanine GMP API supplier for your needs.
A Orellanine CoA (Certificate of Analysis) is a formal document that attests to Orellanine's compliance with Orellanine specifications and serves as a tool for batch-level quality control.
Orellanine CoA mostly includes findings from lab analyses of a specific batch. For each Orellanine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Orellanine may be tested according to a variety of international standards, such as European Pharmacopoeia (Orellanine EP), Orellanine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Orellanine USP).
