

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Oncorena Receives FDA Approval to Initiate Studies in the US
Details : ONC175 is a synthetically produced orellanine, which is highly specific to the kidney and induces irreversible renal failure. Currently being investigated for renal cell carcinoma.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
March 18, 2025
Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ONC175 (orellanine) is the highly selective organ-targeted chemotherapy with potent anti-tumor effects metastatic renal cancer. The interim data from phase 1b further strengthens the previously reported promising safety and efficacy data.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
September 04, 2023
Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell Carcinoma
Details : Orellanine is a Protein drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Carcinoma, Renal Cell.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
March 18, 2022
Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Karolinska University Hospital
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Phase I-II clinical trial of the first-in-class compound Orellanine, found in mushrooms of the Cortinarius family initiated and demonstrated powerful anti-tumor effects on metastatic kidney cancer in different preclinical models.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
February 01, 2022
Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Karolinska University Hospital
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Linc AB
Deal Size : $17.7 million
Deal Type : Financing
Details : The capital will primarily fund Oncorena’s first clinical study, a phase I/II study with orellanine in patients with advanced kidney cancer undergoing dialysis. Orellanine is found in mushrooms of the Cortinarius family.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Undisclosed
December 23, 2021
Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Linc AB
Deal Size : $17.7 million
Deal Type : Financing

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Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Preclinical evidence shows that orellanine, a well known fungus toxin, specifically exerts powerful anti-tumor effects on metastatic renal cancer in different preclinical models.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
March 01, 2021
Lead Product(s) : Orellanine
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
