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Details:

BT-11 (omilancor) is a novel, oral, gut-restricted therapeutic targeting the lanthionine synthetase C-like 2 (LANCL2) pathway which decreases the production of key inflammatory mediators causing ulcerative colitis.


Lead Product(s): Omilancor

Therapeutic Area: Gastroenterology Product Name: BT-11

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 17, 2023

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  • Deals

Details:

NIMML will utilize its proprietary TITAN-X drug development platform, advanced computational modeling, A.I., and bioinformatics capabilities to implement biomarker-driven approaches in NImmune’s upcoming trials involving its LANCL therapeutics, including BT-11 (omilancor).


Lead Product(s): Omilancor

Therapeutic Area: Gastroenterology Product Name: BT-11

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: NImmune Biopharma

Deal Size: $15.0 million Upfront Cash: Undisclosed

Deal Type: Collaboration May 03, 2023

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Details:

BT-11 (omilancor) is a novel, oral, gut-restricted therapeutic targeting the lanthionine synthetase C-like 2 (LANCL2) pathway which decreases the production of key inflammatory mediators causing ulcerative colitis.


Lead Product(s): Omilancor

Therapeutic Area: Gastroenterology Product Name: BT-11

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: NImmune Biopharma

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 22, 2023

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Details:

Landos Biopharma collaborate with Icahn School of Medicine to conduct a Phase 2 trial of omilancor, a novel, oral, gut-restricted, small-molecule investigational drug that targets the Lanthionine Synthetase C-Like 2 (LANCL2) pathway impacting the gastrointestinal tract.


Lead Product(s): Omilancor

Therapeutic Area: Gastroenterology Product Name: BT-11

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Icahn School of Medicine

Deal Size: $3.0 million Upfront Cash: Undisclosed

Deal Type: Collaboration September 20, 2021

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Details:

Discovered using Landos proprietary LANCE® Advanced A.I. platform, omilancor is a novel, oral, gut-restricted small molecule investigational drug that targets the Lanthionine Synthetase C-Like 2 (LANCL2) pathway impacting the gastrointestinal tract.


Lead Product(s): Omilancor

Therapeutic Area: Gastroenterology Product Name: BT-11

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 22, 2021

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Details:

LianBio will receive exclusive rights to develop and commercialize BT-11 and NX-13 in Greater China, South Korea, Singapore, Thailand, Vietnam, Myanmar, Cambodia, Indonesia, and the Philippines.


Lead Product(s): Omilancor

Therapeutic Area: Gastroenterology Product Name: BT-11

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: LianBio

Deal Size: $218.0 million Upfront Cash: $18.0 million

Deal Type: Collaboration May 17, 2021

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