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Chemistry

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Also known as: 2731294-23-6, 54py2pbn7s, 1-(4-(4-amino-7-cyclopropylpyrrolo(2,3-d)pyrimidin-5-yl)-2-fluorophenyl)-3-(5-(1-(trifluoromethyl)cyclopropyl)-1,2-oxazol-3-yl)urea, 1-[4-(4-amino-7-cyclopropylpyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-3-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]urea, Refchem:1093845, Ofirnoflastum
Molecular Formula
C23H19F4N7O2
Molecular Weight
501.4  g/mol
InChI Key
MJUUWYZZPRAKCW-UHFFFAOYSA-N
FDA UNII
54PY2PBN7S

Ofirnoflast
1 2D Structure

Ofirnoflast

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[4-(4-amino-7-cyclopropylpyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-3-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]urea
2.1.2 InChI
InChI=1S/C23H19F4N7O2/c24-14-7-11(13-9-34(12-2-3-12)20-18(13)19(28)29-10-30-20)1-4-15(14)31-21(35)32-17-8-16(36-33-17)22(5-6-22)23(25,26)27/h1,4,7-10,12H,2-3,5-6H2,(H2,28,29,30)(H2,31,32,33,35)
2.1.3 InChI Key
MJUUWYZZPRAKCW-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
54PY2PBN7S
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 2731294-23-6

2. 54py2pbn7s

3. 1-(4-(4-amino-7-cyclopropylpyrrolo(2,3-d)pyrimidin-5-yl)-2-fluorophenyl)-3-(5-(1-(trifluoromethyl)cyclopropyl)-1,2-oxazol-3-yl)urea

4. 1-[4-(4-amino-7-cyclopropylpyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-3-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]urea

5. Refchem:1093845

6. Ofirnoflastum

7. Ofirnoflast [inn]

8. Ofirnolast [usan]

9. Ofirnoflast (usan/inn)

10. Orb2802265

11. Schembl23966707

12. Schembl29484521

13. Gtpl13227

14. Bdbm522987

15. Us11161852, Compound 10

16. Ex-a10121

17. Ht-6184

18. Example 10 [wo2021242505]

19. Hy-159520

20. D13076

21. 1-(4-(4-amino-7- Cyclopropyl-7h- Pyrrolo[2,3- D]pyrimidin-5-yl)-2- Fluorophenyl)-3-(5-(1- (trifluoromethyl)cyclopropyl)isoxazol- 3-yl)urea

22. N-[4-(4-amino-7-cyclopropyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-n'-[5-[1-(trifluoromethyl)cyclopropyl]-3-isoxazolyl]urea

23. N-[4-(4-amino-7-cyclopropyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-n'-{5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl}urea

24. Urea, N-(4-(4-amino-7-cyclopropyl-7h-pyrrolo(2,3-d)pyrimidin-5-yl)-2-fluorophenyl)-n'-(5-(1-(trifluoromethyl)cyclopropyl)-3-isoxazolyl)-

2.4 Create Date
2021-12-13
3 Chemical and Physical Properties
Molecular Weight 501.4 g/mol
Molecular Formula C23H19F4N7O2
XLogP33.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area124
Heavy Atom Count36
Formal Charge0
Complexity842
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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Looking for 2731294-23-6 / Ofirnoflast API manufacturers, exporters & distributors?

Ofirnoflast manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Ofirnoflast API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Ofirnoflast manufacturer or Ofirnoflast supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ofirnoflast manufacturer or Ofirnoflast supplier.

API | Excipient name

Ofirnoflast

Synonyms

2731294-23-6, 54py2pbn7s, 1-(4-(4-amino-7-cyclopropylpyrrolo(2,3-d)pyrimidin-5-yl)-2-fluorophenyl)-3-(5-(1-(trifluoromethyl)cyclopropyl)-1,2-oxazol-3-yl)urea, 1-[4-(4-amino-7-cyclopropylpyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-3-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]urea, Refchem:1093845, Ofirnoflastum

Cas Number

2731294-23-6

Unique Ingredient Identifier (UNII)

54PY2PBN7S

Ofirnoflast Manufacturers

A Ofirnoflast manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ofirnoflast, including repackagers and relabelers. The FDA regulates Ofirnoflast manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ofirnoflast API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ofirnoflast Suppliers

A Ofirnoflast supplier is an individual or a company that provides Ofirnoflast active pharmaceutical ingredient (API) or Ofirnoflast finished formulations upon request. The Ofirnoflast suppliers may include Ofirnoflast API manufacturers, exporters, distributors and traders.

Ofirnoflast GMP

Ofirnoflast Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ofirnoflast GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Ofirnoflast GMP manufacturer or Ofirnoflast GMP API supplier for your needs.

Ofirnoflast CoA

A Ofirnoflast CoA (Certificate of Analysis) is a formal document that attests to Ofirnoflast's compliance with Ofirnoflast specifications and serves as a tool for batch-level quality control.

Ofirnoflast CoA mostly includes findings from lab analyses of a specific batch. For each Ofirnoflast CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ofirnoflast may be tested according to a variety of international standards, such as European Pharmacopoeia (Ofirnoflast EP), Ofirnoflast JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ofirnoflast USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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