Find Nevanimibe manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 133825-80-6, Nevanimibe [usan], Pd-132301, Atr-101 free base, 1-(2,6-diisopropylphenyl)-3-((1-(4-(dimethylamino)phenyl)cyclopentyl)methyl)urea, Chembl46423
Molecular Formula
C27H39N3O
Molecular Weight
421.6  g/mol
InChI Key
PKKNCEXEVUFFFI-UHFFFAOYSA-N
FDA UNII
VK9OS8R205

Nevanimibe
Nevanimibe is under investigation in clinical trial NCT03053271 (A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome).
1 2D Structure

Nevanimibe

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[[1-[4-(dimethylamino)phenyl]cyclopentyl]methyl]-3-[2,6-di(propan-2-yl)phenyl]urea
2.1.2 InChI
InChI=1S/C27H39N3O/c1-19(2)23-10-9-11-24(20(3)4)25(23)29-26(31)28-18-27(16-7-8-17-27)21-12-14-22(15-13-21)30(5)6/h9-15,19-20H,7-8,16-18H2,1-6H3,(H2,28,29,31)
2.1.3 InChI Key
PKKNCEXEVUFFFI-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C)C1=C(C(=CC=C1)C(C)C)NC(=O)NCC2(CCCC2)C3=CC=C(C=C3)N(C)C
2.2 Other Identifiers
2.2.1 UNII
VK9OS8R205
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Damp-cmumep

2. N-(2,6-bis(isopropyl)phenyl)-n'-((1-(4-(dimethylaminomethyl)phenyl)cyclopentyl)methyl)urea

2.3.2 Depositor-Supplied Synonyms

1. 133825-80-6

2. Nevanimibe [usan]

3. Pd-132301

4. Atr-101 Free Base

5. 1-(2,6-diisopropylphenyl)-3-((1-(4-(dimethylamino)phenyl)cyclopentyl)methyl)urea

6. Chembl46423

7. Pd 132301

8. Vk9os8r205

9. Nevanimibe (usan)

10. 1-[[1-[4-(dimethylamino)phenyl]cyclopentyl]methyl]-3-[2,6-di(propan-2-yl)phenyl]urea

11. Damp-cmumep

12. Chembl542103

13. N-(2,6-bis(isopropyl)phenyl)-n/'-((1-(4-(dimethylaminomethyl)phenyl)cyclopentyl)methyl)urea

14. Rov

15. Nevanimibe [inn]

16. Unii-vk9os8r205

17. Schembl1119314

18. Dtxsid10928286

19. Bdbm50041735

20. Akos037648690

21. Sb17169

22. Bs-15209

23. Hy-100399

24. Cs-0018785

25. D11300

26. D81212

27. Q27291867

28. N-({1-[4-(dimethylamino)phenyl]cyclopentyl}methyl)-n'-[2,6-di(propan-2-yl)phenyl]urea

29. N-(2,6-bis(1-methylethyl)phenyl)-n'-((1-(4-(dimethylamino)phenyl)cyclopentyl)methyl)urea

30. 1-(2,6-diisopropyl-phenyl)-3-[1-(4-dimethylamino-phenyl)-cyclopentylmethyl]-urea; Hydrochloride

31. N'-({1-[4-(dimethylamino)phenyl]cyclopentyl}methyl)-n-[2,6-di(propan-2-yl)phenyl]carbamimidic Acid

32. N-(2,6-bis(propan-2-yl)phenyl)-n'-((1-(4-(dimethylamino)phenyl) Cyclopentyl)methyl)urea

33. Urea, N-(2,6-bis(1-methylethyl)phenyl)-n'-((1-(4-(dimethylamino)phenyl)cyclopentyl)methyl)-

34. Urea, N-(2,6-bis(1-methylethyl)phenyl)-n'-((1-(4-dimethylamino)phenyl)cyclopentyl)methyl)-

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 421.6 g/mol
Molecular Formula C27H39N3O
XLogP36.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count7
Exact Mass421.309312876 g/mol
Monoisotopic Mass421.309312876 g/mol
Topological Polar Surface Area44.4 Ų
Heavy Atom Count31
Formal Charge0
Complexity543
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 133825-80-6 / Nevanimibe API manufacturers, exporters & distributors?

Nevanimibe manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Nevanimibe API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Nevanimibe manufacturer or Nevanimibe supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Nevanimibe manufacturer or Nevanimibe supplier.

PharmaCompass also assists you with knowing the Nevanimibe API Price utilized in the formulation of products. Nevanimibe API Price is not always fixed or binding as the Nevanimibe Price is obtained through a variety of data sources. The Nevanimibe Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Nevanimibe

Synonyms

133825-80-6, Nevanimibe [usan], Pd-132301, Atr-101 free base, 1-(2,6-diisopropylphenyl)-3-((1-(4-(dimethylamino)phenyl)cyclopentyl)methyl)urea, Chembl46423

Cas Number

133825-80-6

Unique Ingredient Identifier (UNII)

VK9OS8R205

About Nevanimibe

Nevanimibe is under investigation in clinical trial NCT03053271 (A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome).

Nevanimibe Manufacturers

A Nevanimibe manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Nevanimibe, including repackagers and relabelers. The FDA regulates Nevanimibe manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Nevanimibe API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Nevanimibe Suppliers

A Nevanimibe supplier is an individual or a company that provides Nevanimibe active pharmaceutical ingredient (API) or Nevanimibe finished formulations upon request. The Nevanimibe suppliers may include Nevanimibe API manufacturers, exporters, distributors and traders.

Nevanimibe GMP

Nevanimibe Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Nevanimibe GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Nevanimibe GMP manufacturer or Nevanimibe GMP API supplier for your needs.

Nevanimibe CoA

A Nevanimibe CoA (Certificate of Analysis) is a formal document that attests to Nevanimibe's compliance with Nevanimibe specifications and serves as a tool for batch-level quality control.

Nevanimibe CoA mostly includes findings from lab analyses of a specific batch. For each Nevanimibe CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Nevanimibe may be tested according to a variety of international standards, such as European Pharmacopoeia (Nevanimibe EP), Nevanimibe JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Nevanimibe USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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