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ACTIVE PHARMA INGREDIENTS

7 API Suppliers, 2 USDMF, 3 CEP/COS, 2 JDMF, 6 NDC API, 1 Listed Suppliers, $ API Reference Price

7 API Suppliers
2 USDMF
3 CEP/COS
2 JDMF
6 NDC API
1 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

37 FDF Dossiers, 25 Canada, 1 South Africa, 11 Listed Dossiers

37 FDF Dossiers
25 Canada
1 South Africa
11 Listed Dossiers

RELATED EXCIPIENT COMPANIES

2 EUROAPI, 1 Rochem International Inc, 4 SPI Pharma, 1 DKSH, 4 Faran Shimi Pharmaceutical, 3 Gangwal Healthcare, 2 Kewpie Corporation, 4 Nanjing Well Pharmaceutical, 6 Actylis, 4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 8 BASF, 4 DFE Pharma, 1 Finar, 4 Gangwal Chemicals, 1 Ideal Cures Pvt Ltd, 2 Ingredion Pharma Solutions, 21 Kerry, 9 Microlex e.U, 1 Pharmatrans-Sanaq, 5 Pluviaendo, 2 Prachin Chemical, 13 Roquette, 1 Seppic, 3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 9 Sigachi Industries, 1 Valens Pharmachem, 2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

49 Fillers, Diluents & Binders, 18 Direct Compression, 14 Granulation, 12 Thickeners and Stabilizers, 12 Lubricants & Glidants, 11 Parenteral, 10 Co-Processed Excipients, 8 Emulsifying Agents, 7 Disintegrants & Superdisintegrants, 7 Taste Masking, 7 Topical, 7 Controlled & Modified Release, 7 Coating Systems & Additives, 5 Chewable & Orodispersible Aids, 4 Film Formers & Plasticizers, 3 Solubilizers, 2 API Stability Enhancers, 1 Surfactant & Foaming Agents, 1 Rheology Modifiers

DIGITAL CONTENT

1 Data Compilation #PharmaFlow, 15 News #PharmaBuzz

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1 Data Compilation #PharmaFlow
15 News #PharmaBuzz

MARKET PLACE

11 APIs, 4 EXCIPIENTS, 1 Intermediates

marketPlace
11 APIs
4 EXCIPIENTS
1 Intermediates

REF. STANDARDS & IMPURITIES

3 EDQM , 1 USP , 3 Others

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3 EDQM
1 USP
3 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

118RELATED EXCIPIENT COMPANIES

185EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

API REF. PRICE (USD/KG)

$ 201

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Regulatory FDF Prices

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MARKET PLACE

API

FDF

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

Chemistry

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Also known as: 59-51-8, Methionine, Racemethionine, Acimetion, Lobamine, Banthionine

Molecular Formula

C₅H₁₁NO₂S

Molecular Weight

149.21 g/mol

InChI Key

FFEARJCKVFRZRR-UHFFFAOYSA-N

FDA UNII

73JWT2K6T3

A sulfur-containing essential L-amino acid that is important in many body functions.

1 2D Structure

Methionine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-amino-4-methylsulfanylbutanoic acid

2.1.2 InChI

InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

2.1.3 InChI Key

FFEARJCKVFRZRR-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CSCCC(C(=O)O)N

2.2 Other Identifiers

2.2.1 UNII

73JWT2K6T3

2.3 Synonyms

2.3.1 MeSH Synonyms

1. L-isomer Methionine

2. L-methionine

3. Liquimeth

4. Methionine

5. Methionine, L Isomer

6. Methionine, L-isomer

7. Pedameth

2.3.2 Depositor-Supplied Synonyms

1. 59-51-8

2. Methionine

3. Racemethionine

4. Acimetion

5. Lobamine

6. Banthionine

7. Cynaron

8. Meonine

9. Mertionin

10. Metione

11. Pedameth

12. Urimeth

13. Dyprin

14. Neston

15. H-dl-met-oh

16. (+-)-methionine

17. Dl-methioninum

18. Dl-2-amino-4-(methylthio)butanoic Acid

19. D,l-methionine

20. Methionine, Dl-

21. Fema No. 3301

22. 2-amino-4-methylsulfanylbutanoic Acid

23. Methionine Dl-form

24. 2-amino-4-(methylsulfanyl)butanoic Acid

25. 2-amino-4-(methylthio)butyric Acid

26. 2-amino-4-(methylthio)butanoic Acid

27. Methilonin

28. Racemethionine [usan]

29. Dl-2-amino-4-(methylthio)-butyric Acid

30. Alpha-amino-gamma-methylmercaptobutyric Acid

31. Nsc 9241

32. Mfcd00063096

33. Alpha-amino-gamma-(methylthio)butyric Acid

34. Nsc-9241

35. (+/-)-2-amino-4-(methylmercapto)butyric Acid

36. Dl-2-amino-4-(methylthio)butyric Acid

37. 73jwt2k6t3

38. Dl-methionine (racemethionine)

39. Chebi:16811

40. 2-amino-4-methylthiobutanoic Acid

41. Poly-l-methionine

42. Nsc22946

43. 26062-47-5

44. 2-amino-4-(methylmercapto)butyric Acid

45. Ncgc00159431-02

46. Dl-methionine (jan)

47. Racemethionine (usan)

48. .alpha.-amino-.gamma.-methylmercaptobutyric Acid

49. Dl-methionine [jan]

50. R-methionine

51. Methionine, Amorphous

52. Methionine Dl-

53. Ccris 3717

54. (+/-)-methionine

55. Einecs 200-432-1

56. Unii-73jwt2k6t3

57. Petameth

58. Amurex

59. Metion

60. Dl-methionin

61. Hmet

62. Ai3-18475

63. Mfcd00002622

64. Nsc-45689

65. Racemethionine [usan:usp:nf]

66. Dl-methionine;

67. Padameth (tn)

68. Alpha-amino-gamma-methylmercaptobutyric Acid (van)

69. Dl-met

70. Dl-2-amino-4-methylthiobutanoic Acid

71. ((c)i)-methionine

72. Racemethionine, Usan

73. 2-amino-4-methylsulfanyl-butanoic Acid

74. 7005-18-7

75. Dextro,laevo-methionine

76. Methionine,l-

77. 2-amino-4-(methylthio)-butyric Acid

78. (.+-.)-methionine

79. Dsstox_cid_821

80. (.+/-.)-methionine

81. Met248

82. Dl-methionine, >=99%

83. Schembl4225

84. Dl-methionine [fcc]

85. Dsstox_rid_75809

86. Wln: Qvyz2s1 -l

87. Dsstox_gsid_20821

88. D,l-methionine [fhfi]

89. Dl-methionine [mart.]

90. Chembl274119

91. Dl-methionine [who-dd]

92. Dl-methionine [who-ip]

93. H3csch2ch2ch(nh2)cooh

94. Racemethionine [usp-rs]

95. Dtxsid9020821

96. Methionine Dl-form [mi]

97. Bdbm86195

98. Fema 3301

99. Nsc9241

100. Dl-ch3sch2ch2ch(nh2)cooh

101. Dl-methionine, 99%, Fcc, Fg

102. Cas_6137

103. Dl-methionine [ep Impurity]

104. Hy-n0325

105. Nsc_6137

106. Nsc45689

107. Tox21_111663

108. Bbl009323

109. Cas_84815

110. Dl-methionine [ep Monograph]

111. Dl-methionine, >=99.0% (nt)

112. Nsc_84815

113. Nsc118113

114. Nsc522406

115. S9344

116. Stk802463

117. 2-amino-4-(methylthio) Butyric Acid

118. 2-amino-4-methylsulfanyl-butyric Acid

119. Akos000118924

120. Akos016050523

121. Dl-methioninum [who-ip Latin]

122. Ccg-266195

123. Db13972

124. Nsc-118113

125. Nsc-522406

126. Cas-59-51-8

127. Butyric Acid, 2-amino-4-(methylthio)-

128. Ncgc00159431-03

129. Ncgc00159431-04

130. Ds-16180

131. Sy004418

132. L(-)-amino-.gamma.-methylthiobutyric Acid

133. Db-029693

134. .gamma.-methylthio-.alpha.-aminobutyric Acid

135. Am20100433

136. Cs-0008889

137. Ft-0625489

138. Ft-0625547

139. Ft-0671134

140. Ft-0690213

141. Ft-0693483

142. Ft-0698675

143. Ft-0699633

144. Ft-0771524

145. M0463

146. C01733

147. D04983

148. D72471

149. Dl-methionine, Saj Special Grade, >=99.0%

150. Dl-methionine, Vetec(tm) Reagent Grade, 98%

151. L-.gamma.-methylthio-.alpha.-aminobutyric Acid

152. Z00115

153. Ab00373904-02

154. 063m096

155. Q180341

156. Sr-01000944495

157. J-300193

158. L-.alpha.-amino-.gamma.-methylmercaptobutyric Acid

159. Q-201029

160. Sr-01000944495-1

161. Z57127440

162. F0001-1544

163. C6115881-e914-4ea8-a21a-dcbf67783824

164. Dl-methionine, European Pharmacopoeia (ep) Reference Standard

165. Racemethionine, United States Pharmacopeia (usp) Reference Standard

166. 33807-07-7

167. Dl-methionine, Bioreagent, Suitable For Cell Culture, Suitable For Insect Cell Culture, >=99%

2.4 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	C₅H₁₁NO₂S
Molecular Weight	149.21 g/mol
XLogP3	-1.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	149.05104977 g/mol
Monoisotopic Mass	149.05104977 g/mol
Topological Polar Surface Area	88.6 Å²
Heavy Atom Count	9
Formal Charge	0
Complexity	97
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 ATC Code

V - Various

V03 - All other therapeutic products

V03A - All other therapeutic products

V03AB - Antidotes

V03AB26 - Methionine

API SUPPLIERS

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USDMF

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CEP/COS

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JDMF

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NDC API

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Listed Suppliers

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API Reference Price

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Methionine

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

7 API Suppliers

2 USDMF

3 CEP/COS

2 JDMF

6 NDC API

1 Listed Suppliers

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

37 FDF Dossiers

25 Canada

1 South Africa

11 Listed Dossiers

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6 Actylis

4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

8 BASF

4 DFE Pharma

1 Finar

4 Gangwal Chemicals

1 Ideal Cures Pvt Ltd

2 Ingredion Pharma Solutions

21 Kerry

9 Microlex e.U

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2 Prachin Chemical

13 Roquette

1 Seppic

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9 Sigachi Industries

1 Valens Pharmachem

2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

49 Fillers, Diluents & Binders

18 Direct Compression

14 Granulation

12 Thickeners and Stabilizers

12 Lubricants & Glidants

11 Parenteral

10 Co-Processed Excipients

8 Emulsifying Agents

7 Disintegrants & Superdisintegrants

7 Taste Masking

7 Topical

7 Controlled & Modified Release

7 Coating Systems & Additives

5 Chewable & Orodispersible Aids

4 Film Formers & Plasticizers

3 Solubilizers

2 API Stability Enhancers

1 Surfactant & Foaming Agents

1 Rheology Modifiers

DIGITAL CONTENT

1 Data Compilation #PharmaFlow

15 News #PharmaBuzz

MARKET PLACE

11 APIs

4 EXCIPIENTS

1 Intermediates

REF. STANDARDS & IMPURITIES

3 EDQM

1 USP

3 Others

ACTIVE PHARMA INGREDIENTS

0INTERMEDIATES