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Details:
PF-06741086 (marstacimab) is a human monoclonal immunoglobulin G isotype, subclass 1 (IgG1) that targets the TFPI and development as a prophylactic and subcutaneous treatment for severe hemophilia A or moderately severe to severe hemophilia B with or without inhibitors.
Lead Product(s): Marstacimab
Therapeutic Area: Genetic Disease Product Name: PF-06741086
Highest Development Status: Phase IIIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable December 11, 2023
Details:
PF-06741086 (marstacimab) is a human monoclonal immunoglobulin G isotype, subclass 1 (IgG1) that targets the TFPI and development as a prophylactic and subcutaneous treatment for severe hemophilia A or moderately severe to severe hemophilia B with or without inhibitors.
Lead Product(s): Marstacimab
Therapeutic Area: Genetic Disease Product Name: PF-06741086
Highest Development Status: Phase IIIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable May 30, 2023
Details:
The completed Phase 2 study results demonstrated that treatment with marstacimab resulted in significant (>75%) reductions in ABR for all participants in the study population.
Lead Product(s): Marstacimab
Therapeutic Area: Genetic Disease Product Name: PF-06741086
Highest Development Status: Phase IIIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable November 23, 2020
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